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Researchers use novel phage therapy to treat patient infected with multidrug-resistant bacterium

Scientists and physicians at University of California San Diego School of Medicine, working with colleagues at the U.S. Navy Medical Research Center - Biological Defense Research Directorate, Texas A&M University, a San Diego-based biotech and elsewhere, have successfully used an experimental therapy involving bacteriophages -- viruses that target and consume specific strains of bacteria -- to treat a patient near death from a multidrug-resistant bacterium.

25 Apr 2017

Researchers identify new rare genetic variants linked to extreme longevity

The search for the genetic determinants of extreme longevity has been challenging, with the prevalence of centenarians (people older than 100) just one per 5,000 population in developed nations.

25 Apr 2017

Neurobiologists use skin stem cells to generate new microglia

Using human skin cells, University of California, Irvine neurobiologists and their colleagues have created a method to generate one of the principle cell types of the brain called microglia, which play a key role in preserving the function of neural networks and responding to injury and disease.

25 Apr 2017

Scientists create new technique for studying how chlamydia interacts with immune system

Scientists at the Wellcome Trust Sanger Institute and their collaborators at the University of British Columbia have created an innovative technique for studying how chlamydia interacts with the human immune system.

25 Apr 2017

Genetic factors may increase person's risk for adverse effects of synthetic cannabinoids

Synthetic cannabinoid abuse is a growing problem in the United States, with new versions of the drugs coming on the market every year. New research is examining how the body processes these man-made drugs and the role that genetics might play in their metabolism.

25 Apr 2017

Synthetic scaffold loaded with cancer-fighting T cells effectively shrinks solid tumors

Cellular therapy hasn't had much success in fighting solid tumors, partly because it's been difficult to deliver anti-cancer T cells to the tumors.

25 Apr 2017

Study shows how gut microbiota may play role in effectiveness of chemotherapy drugs

The bacteria residing in your digestive tract, or your gut microbiota, may play an important role in your ability to respond to chemotherapy drugs in the clinic, according to a new study by scientists at the University of Massachusetts Medical School.

25 Apr 2017

Scientists use stem cells to identify underlying cellular defects that cause Angelman syndrome

Researchers at UConn Health used stem cells derived from patients with Angelman syndrome to identify the underlying cellular defects that cause the rare neurogenetic disorder, an important step in the ongoing search for potential treatments for Angelman and a possible cure.

25 Apr 2017

Penn State researchers receive NIH funding to explore malaria transmission in Southeast Asia

Researchers at Penn State have received more than $1 million in first-year funding from the National Institutes of Health to investigate malaria transmission in Southeast Asia with a goal of working toward the disease's elimination in the region.

24 Apr 2017

Whole-exome sequencing may routinely miss detecting some disease-causing genes, say researchers

Whole-exome DNA sequencing -- a technology that saves time and money by sequencing only protein-coding regions and not the entire genome -- may routinely miss detecting some genetic variations associated with disease, according to Penn State researchers who have developed new ways to identify such omissions.

24 Apr 2017

Scientists receive $2.8 million federal grant for diabetic cardiomyopathy research

Researchers from Georgia State University's Center for Molecular & Translational Medicine have received a four-year, $2.8 million federal grant to study diabetic cardiomyopathy, diabetes-related changes in the structure and function of the heart muscle.

24 Apr 2017

Researchers discover gene that may play role in restoring hearing after noise exposure

Researchers have discovered that a protein implicated in human longevity may also play a role in restoring hearing after noise exposure. The findings, where were published in the journal Scientific Reports, could one day provide researchers with new tools to prevent hearing loss.

24 Apr 2017

$Women at highest genetic risk for fracture benefit most from hormone therapy, study finds$

Women at highest genetic risk for fracture benefit most from hormone therapy, study finds

Women at the highest genetic risk for fracture benefit the most from hormone therapy, according to a first-of-its-kind study led by researchers at the University at Buffalo.

24 Apr 2017

Brain genes influence our eating habits, study finds

Differences in the genetic make-up of our brains may account for the particular food preferences people have and their varying ability to stick to diets, according to new research.

24 Apr 2017

Study shows how brain genes influence food intake and dietary preferences

Have you ever wondered why you keep eating certain foods, even if you know they are not good for you? Gene variants that affect the way our brain works may be the reason, according to a new study. The new research could lead to new strategies to empower people to enjoy and stick to their optimal diets.

24 Apr 2017

Transgenic fruit flies can shed light on genetic mutations that underlie kidney disease in humans

An off-the-shelf dietary supplement available for pennies per dose demonstrated the ability to reverse cellular damage linked to specific genetic mutations in transgenic fruit flies, an experimental model of genetic mutation-induced renal cell injury that features striking similarities to humans, a Children's National Health System research team reports April 20 in Journal of the American Society of Nephrology.

21 Apr 2017

Researchers awarded NIAID grant to develop new tools for eliminating drug-resistant malaria

The University of Maryland School of Medicine has been awarded a $9 million seven-year grant by the National Institute of Allergy and Infectious Diseases to develop new tools to help eliminate drug-resistant malaria in Southeast Asia and other regions where the disease is common.

21 Apr 2017

Positive CHMP opinion recognizes efficacy of Biogen’s SPINRAZA for treatment of spinal muscular atrophy

Biogen today announced the Committee for Medicinal Products for Human Use of the European Medicines Agency adopted a positive opinion recommending the granting of a marketing authorization for SPINRAZA to treat patients with spinal muscular atrophy (SMA).

21 Apr 2017

Researchers use gene-editing tool to restore visual function in mouse models of retinitis pigmentosa

Using the gene-editing tool CRISPR/Cas9, researchers at University of California San Diego School of Medicine and Shiley Eye Institute at UC San Diego Health, with colleagues in China, have reprogrammed mutated rod photoreceptors to become functioning cone photoreceptors, reversing cellular degeneration and restoring visual function in two mouse models of retinitis pigmentosa.

21 Apr 2017

Researchers discover how protein aggregation triggers aging

Not only does our way of life determine how long we live but so too does our genetic material. Of particular importance here is a genetic program that is controlled by the insulin receptor. A team of researchers from the Universities of Cologne and Bonn has now discovered how protein aggregation affects this genetic program and thus triggers aging.

21 Apr 2017

Genetic News and Research

Researchers use novel phage therapy to treat patient infected with multidrug-resistant bacterium

Researchers identify new rare genetic variants linked to extreme longevity

Neurobiologists use skin stem cells to generate new microglia

Scientists create new technique for studying how chlamydia interacts with immune system

Genetic factors may increase person's risk for adverse effects of synthetic cannabinoids

Synthetic scaffold loaded with cancer-fighting T cells effectively shrinks solid tumors

Study shows how gut microbiota may play role in effectiveness of chemotherapy drugs

Scientists use stem cells to identify underlying cellular defects that cause Angelman syndrome

Penn State researchers receive NIH funding to explore malaria transmission in Southeast Asia

Whole-exome sequencing may routinely miss detecting some disease-causing genes, say researchers

Scientists receive $2.8 million federal grant for diabetic cardiomyopathy research

Researchers discover gene that may play role in restoring hearing after noise exposure

Women at highest genetic risk for fracture benefit most from hormone therapy, study finds

Brain genes influence our eating habits, study finds

Study shows how brain genes influence food intake and dietary preferences

Transgenic fruit flies can shed light on genetic mutations that underlie kidney disease in humans

Researchers awarded NIAID grant to develop new tools for eliminating drug-resistant malaria

Positive CHMP opinion recognizes efficacy of Biogen’s SPINRAZA for treatment of spinal muscular atrophy

Researchers use gene-editing tool to restore visual function in mouse models of retinitis pigmentosa

Researchers discover how protein aggregation triggers aging

Genetics & Genomics - Second Edition eBook

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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