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Gene radiotherapy system shows promise for fighting treatment-resistant cancer cells

A gene radiotherapy system that detects and treats cancer cells that are resistant to traditional forms of chemotherapy and radiation showed success in the laboratory and could eventually prove beneficial for cancer patients, according to researchers at the Society of Nuclear Medicine's 55th Annual Meeting.

16 Jun 2008

Aerobics increases blood protein that may suppress appetite

Three months of aerobic exercise decreased body fat and calorie intake in overweight and obese people, according to a new study, and the researchers believe that changes to a central nervous system factor are responsible. The results will be presented at The Endocrine Society's 90th Annual Meeting in San Francisco.

16 Jun 2008

Compound in grapes and red wine may help battle obesity

Resveratrol, a compound present in grapes and red wine, reduces the number of fat cells and may one day be used to treat or prevent obesity, according to a new study. The results will be presented at The Endocrine Society's 90th Annual Meeting in San Francisco.

16 Jun 2008

Discovery of mechanisms that direct cholinergic synapse assembly between neurons in vivo

Rapid information processing in the nervous system requires synapses, specialized contact sites between nerve cells and their targets. One particular synapse type, cholinergic, uses the chemical transmitter acetylcholine to communicate between nerve cells. Cholinergic synapses are essential for normal learning and memory, arousal, attention, and all autonomic (involuntary) nervous system functions.

16 Jun 2008

Fluorescent-probe in worm creates real-time "view" of cellular stress

Scientists at the University at Buffalo have created a mutant worm that changes color when it moves. The color change is generated by an optical sensor called stFRET. The sensor is composed of a pair of fluorescent molecules connected by a molecular spring that is inserted into structural proteins in the worm's cells.

16 Jun 2008

PolyTherics and Alligator Bioscience announce strategic collaboration for optimisation of next generation biopharmaceuticals

PolyTherics Ltd, a biopharmaceutical company specialised in the targeted application of polymers to biopharmaceuticals, and Alligator Bioscience AB ("Alligator"), a biotechnology company applying proprietary technology to the improvement of proteins, today announced the establishment of a new alliance.

16 Jun 2008

European researchers take lid off the genome

European researchers have made significant progress unravelling how genes are governed and why this sometimes goes wrong in disease.

15 Jun 2008

Collaborative effort by FDA and EMEA expected to yield additional safety data when assessing new drugs

In the first use of a framework allowing submission of a single application to the two agencies, the Food and Drug Administration (FDA) and the European Medicines Agency (EMEA) worked together to allow drug companies to submit the results of seven new tests that evaluate kidney damage during animal studies of new drugs. The tests measure the levels of seven key proteins or "biomarkers" found in urine that can provide additional information about drug-induced damage to kidney cells, also known as renal toxicity.

15 Jun 2008

Nanoparticle delivers antisense agent to tumors

A multifunctional drug delivery system consisting of a lipid-based nanoparticle, a standard anticancer drug, and a short nucleic acid designed to augment the activity of that drug has demonstrated the ability to treat drug-resistant tumor cells.

15 Jun 2008

Targeted quantum rods probe blood-brain barrier

One of the chief difficulties in treating brain tumors involves getting potential tumor-killing drugs across the blood-brain barrier and into the brain.

15 Jun 2008

New technique provides greater understanding of how drugs get in and out of cells in our bodies

A team led by female scientists at the Universities of Bristol and Cambridge has developed an exciting new technique which may lead to a greater understanding of how drugs get in and out of the cells in our bodies. The method identifies the structures that guard the entrance and exits to cells.

15 Jun 2008

Scientists identify molecular trick that may explain part of Salmonella's fierceness

Salmonella is serving up a surprise not only for tomato lovers around the country but also for scientists who study the rod-shaped bacterium that causes misery for millions of people.

15 Jun 2008

Researchers find gamma-secretase modulators being tested for Alzheimer’s work in unexpected and beneficial ways

Researchers at Mayo Clinic, with their national and international collaborators, have discovered how a class of agents now in testing to treat Alzheimer's disease work, and say they may open up an avenue of drug discovery for this disease and others.

11 Jun 2008

Smad proteins regulate microRNA processing

Researchers at Tufts University School of Medicine and Tufts Medical Center have found that Smad proteins regulate microRNA (miRNA) processing.

11 Jun 2008

Compugen announces discovery of novel drug targets for cancer antibody therapeutics

Compugen Ltd. announced today the discovery of more than ten novel targets of antibody therapy for various types of solid and hematopoietic cancer.

11 Jun 2008

Without increased funding, California's dominance and public health are threatened, according to new report

The California Healthcare Institute (CHI) and PricewaterhouseCoopers (PwC) today released a report, "The National Institutes of Health: Fueling Healthcare Innovation in California," urging legislators to support increased funding for the National Institutes of Health (NIH) - the backbone of the biomedical industry in California, which employs more than 267,000 people in high wage jobs.

11 Jun 2008

Maxygen receives approval for trial of factor VIIa in UK

Maxygen, Inc. today announced that it has filed a Clinical Trial Authorization (CTA) and received the necessary approvals in the United Kingdom to initiate a first-in-human Phase I trial of MAXY-VII in hemophilia patients.

11 Jun 2008

Viruses genetically designed to kill cancer cells influence tumor blood-vessel growth

Viruses genetically designed to kill cancer cells offer a promising strategy for treating incurable brain tumors such as glioblastoma, but the body's natural defenses often eliminate the viruses before they can eliminate the tumor.

11 Jun 2008

Drug combo offers new approach for reversing type 1 diabetes

Promising results from a study that tested a new approach for reversing Type 1 diabetes are being presented this week at the American Diabetes Association's 68th Annual Scientific Session in San Francisco.

11 Jun 2008

European research project to explore Alzheimer's diagnosis

VTT Technical Research Centre of Finland, GE Healthcare, a division of the General Electric Company (NYSE: GE) and a Consortium of leading research institutions across Europe announced the PredictAD project, a research collaboration aimed at developing new diagnostic procedures for patients with Alzheimer's disease.

10 Jun 2008

G Protein News and Research

Gene radiotherapy system shows promise for fighting treatment-resistant cancer cells

Aerobics increases blood protein that may suppress appetite

Compound in grapes and red wine may help battle obesity

Discovery of mechanisms that direct cholinergic synapse assembly between neurons in vivo

Fluorescent-probe in worm creates real-time "view" of cellular stress

PolyTherics and Alligator Bioscience announce strategic collaboration for optimisation of next generation biopharmaceuticals

European researchers take lid off the genome

Collaborative effort by FDA and EMEA expected to yield additional safety data when assessing new drugs

Nanoparticle delivers antisense agent to tumors

Targeted quantum rods probe blood-brain barrier

New technique provides greater understanding of how drugs get in and out of cells in our bodies

Scientists identify molecular trick that may explain part of Salmonella's fierceness

Researchers find gamma-secretase modulators being tested for Alzheimer’s work in unexpected and beneficial ways

Smad proteins regulate microRNA processing

Compugen announces discovery of novel drug targets for cancer antibody therapeutics

Without increased funding, California's dominance and public health are threatened, according to new report

Maxygen receives approval for trial of factor VIIa in UK

Viruses genetically designed to kill cancer cells influence tumor blood-vessel growth

Drug combo offers new approach for reversing type 1 diabetes

European research project to explore Alzheimer's diagnosis

Industry Focus eBook - Cell biology (5th edition) eBook

How ELRIG Is Helping Mid-Career Scientists Navigate Leadership, Career Change and Redundancy

The role of UV-Vis in biopharma QC

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