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Daily regimen of ibuprofen can ward off Alzheimer's disease, say neuroscientists

A Vancouver-based research team led by Canada's most cited neuroscientist, Dr. Patrick McGeer, has successfully carried out studies suggesting that, if started early enough, a daily regimen of the non-prescription NSAID (nonsteroidal anti-inflammatory drug) ibuprofen can prevent the onset of Alzheimer's disease.

26 Mar 2018

Using machine learning to predict C. difficile infection risk

Researchers have developed a series of machine learning models that can predict a patient’s risk of infection by C. difficile, a gastrointestinal pathogen.

26 Mar 2018

Two immunotherapies used together for the first time to fight against solid tumors

Two immunotherapies - one that enables the T-cells a patient already has to better attack a tumor and another that can produce an independent and vigorous immune response - are being given together for the first time to help more patients wage a stronger war on a wide range of solid tumors, researchers say.

26 Mar 2018

Initiating opioid analgesic decreases use of antipsychotics, benzodiazepines in Alzheimer's patients

Initiating an opioid analgesic reduced the use of antipsychotics and benzodiazepines in persons with Alzheimer's disease, a recent study from the University of Eastern Finland shows.

26 Mar 2018

Research provides better understanding of how some cancer cells resist treatment

An international team of researchers led by Lucio Miele, MD, PhD, Professor and Chair of Genetics at LSU Health New Orleans School of Medicine, and Justin Stebbing, BM BCh MA, PhD, Professor of Cancer Medicine and Medical Oncology at Imperial College of Medicine in London, has found new genetic mutations that promote the survival of cancer cells.

23 Mar 2018

Researchers probe RNA epigenetics and chromatin structures to predict drug resistance in leukemia

Drug resistance is a major obstacle to effective treatment for patients with cancer and leukemia. Epigenetic modifying drugs have been proven effective for some patients with hematologic malignancies, such as myelodysplastic syndrome (MDS) and acute myeloid leukemia (AML).

23 Mar 2018

Scientists create synthesized antibiotic capable of treating superbugs

A "game changing" new antibiotic which is capable of killing superbugs has been successfully synthesized and used to treat an infection for the first time -- and could lead to the first new class of antibiotic drug in 30 years.

23 Mar 2018

Researchers explore ways to help older adults taper off and stop using sedatives

Older adults, especially those who are admitted to hospitals, are at risk for potentially dangerous side effects if they are taking multiple medicines. Taking several medications at the same time is called polypharmacy.

23 Mar 2018

Non-psychoactive cannabis ingredient could reduce risk of relapse among recovering addicts

A preclinical study in rats has shown that there might be value in using a non-psychoactive and non-addictive ingredient of the Cannabis sativa plant to reduce the risk of relapse among recovering drug and alcohol addicts.

23 Mar 2018

USC researchers create algorithm to optimize substance abuse intervention groups

When it comes to fighting substance abuse, research suggests the company you keep can make the difference between recovery and relapse. So, while group intervention programs can play an important role in preventing substance abuse, especially in at-risk populations such as homeless youth, they can also inadvertently expose participants to negative behaviors.

23 Mar 2018

Fingerprint test accurately and noninvasively detects heroin, cocaine users

A fingerprint test published today in AACC's Clinical Chemistry journal can tell whether someone has taken heroin or cocaine, and accurately distinguishes between drug users versus individuals who were exposed to drug residue in the environment.

23 Mar 2018

Back pain being mismanaged globally

According to a panel of international health experts, back pain is being grossly mismanaged globally. This could be both by ineffective treatments as well as treatment with harmful methods.

23 Mar 2018

Mice getting a new lease of life with anti-aging pills

According to a new study from the researchers at Harvard Medical School and the University of New South Wales, the actually cellular processes that cause aging of the blood vessels have been understood.

23 Mar 2018

Bariatric surgery linked to positive outcomes in very obese adolescents with type 2 diabetes

While it's not news that weight loss and medication control type 2 diabetes, a secondary analysis found that bariatric surgery could potentially be an effective option for very obese adolescents with type 2 diabetes, lowering blood glucose levels, improving weight loss and returning cholesterol and blood pressure levels to normal.

22 Mar 2018

New study identifies key cellular mechanisms behind vascular aging in mice

We are as old as our arteries, the adage goes, so could reversing the aging of blood vessels hold the key to restoring youthful vitality? The answer appears to be yes, at least in mice, according to a new study led by investigators at Harvard Medical School.

22 Mar 2018

New findings could have revolutionary impact on quality of life of older people

Researchers from UNSW and Harvard Medical School have discovered that replacing two naturally occurring molecules in the body could reverse symptoms of aging, potentially influencing how the body responds to and performs exercise.

22 Mar 2018

Researchers find investigational compound to treat triple negative breast cancer after brain metastasis

Researchers at Houston Methodist used computer modeling to find an existing investigational drug compound for leukemia patients to treat triple negative breast cancer once it spreads to the brain.

22 Mar 2018

Graphic: Opioid painkiller is top prescription in 11 states

Americans fill about 4.5 billion prescriptions each year, at a cost of more than $323 billion. But what are we actually buying? In 11 states, the top prescriptions are opioid pain pills that are mixtures of acetaminophen and hydrocodone (brand names Vicodin and Norco), according to new data from GoodRx, an online prescription cost service.

22 Mar 2018

Maternal alcohol use early in pregnancy may be risk factor for infant abdominal malformation

Alcohol use early in the pregnancy by the mother may be a risk factor for a condition in which an infant's intestines develop outside the abdomen, according to a study published in the Journal of Maternal-Fetal & Neonatal Medicine.

22 Mar 2018

Immunotherapy combination increases overall survival in people with kidney cancer, study shows

Treating people with advanced metastatic kidney cancer using a combination of the immunotherapy drugs nivolumab (Opdivo) and ipilimumab (Yervoy) significantly increased overall survival versus treatment with sunitinib (Sutent) alone, according to new findings from researchers at Memorial Sloan Kettering Cancer Center that were reported today in the New England Journal of Medicine.

22 Mar 2018

Drugs News and Research

Daily regimen of ibuprofen can ward off Alzheimer's disease, say neuroscientists

Using machine learning to predict C. difficile infection risk

Two immunotherapies used together for the first time to fight against solid tumors

Initiating opioid analgesic decreases use of antipsychotics, benzodiazepines in Alzheimer's patients

Research provides better understanding of how some cancer cells resist treatment

Researchers probe RNA epigenetics and chromatin structures to predict drug resistance in leukemia

Scientists create synthesized antibiotic capable of treating superbugs

Researchers explore ways to help older adults taper off and stop using sedatives

Non-psychoactive cannabis ingredient could reduce risk of relapse among recovering addicts

USC researchers create algorithm to optimize substance abuse intervention groups

Fingerprint test accurately and noninvasively detects heroin, cocaine users

Back pain being mismanaged globally

Mice getting a new lease of life with anti-aging pills

Bariatric surgery linked to positive outcomes in very obese adolescents with type 2 diabetes

New study identifies key cellular mechanisms behind vascular aging in mice

New findings could have revolutionary impact on quality of life of older people

Researchers find investigational compound to treat triple negative breast cancer after brain metastasis

Graphic: Opioid painkiller is top prescription in 11 states

Maternal alcohol use early in pregnancy may be risk factor for infant abdominal malformation

Immunotherapy combination increases overall survival in people with kidney cancer, study shows

Industry Focus eBook - Cell & Gene Therapy (1st Edition) eBook

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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