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Viewpoints: Selling Obamacare in Arizona; 'Hassle-free' marketplace; Seeking the 'grand bargain'

You may not admit it, but you are a fan of Obamacare and Gov. Jan Brewer knows it. The Republicans who run the Arizona legislature don't like Obamacare. And the Republicans who control the U.S. House of Representatives don't like it. But you do. You may deny it. You may not even know it. But you do. And that will help the governor get her Medicaid expansion plan through the legislature (EJ Montini, 6/6).

11 Jun 2013

Cytosine methylation plays key role in development of childhood ALL

Changes in an epigenetic mechanism that turns expression of genes on and off may be as important as genetic alterations in causing pediatric acute lymphoblastic leukemia, according to a study led by scientists at St. Jude Children's Research Hospital and published in the June 10 online edition of the Journal of Clinical Investigation.

11 Jun 2013

Researchers receive grant from Arthritis Research UK to study genes associated with hip osteoarthritis

Medical research charity Arthritis Research UK has awarded £250,000 to a team of researchers at the University of Bristol and the University of Aberdeen to study which genes can lead to people developing painful and common osteoarthritis of the hip.

11 Jun 2013

Researchers find master regulator of EMT and metastasis

The predominant cause of death in cancer patients is metastasis, the formation of secondary tumors in other organs like the brain, liver, and lungs. Cancer cells detach from the original primary tumor and reach a single cell or group of cells in another organ. The cells of the body normally remain in place through adhering to an extracellular substance. However, cancer cells learn how to release themselves from these bonds and invade surrounding tissues, blood, and the lymphatic system.

11 Jun 2013

New technique for identifying mice in breeding colonies

Immunocompromised mice, created by inactivating the genes that would allow them to recognize and attack donor cells or organs, are critical for studies of bone marrow reconstitution.

10 Jun 2013

New non-invasive test measures methylation of SDC2 gene, detects 87% of colorectal cancer

The average 5-year survival for colorectal cancer (CRC) is less than 10% if metastasis occurs, but can reach 90% if detected early. A new non-invasive test has been developed that measures methylation of the SDC2 gene in tissues and blood sera.

10 Jun 2013

Viewpoints: Will 'rate shock' grow?; Krugman says GOP spite is driving opposition to Medicaid expansion; Determining who owns genes

Any plausible health care reform, the various conservative alternatives to Obamacare included, would necessarily have losers as well as winners, and as far as potential losers go single young men with above-average incomes are not precisely the country's most disadvantaged demographic. If you think the current system is flawless, then I suppose any rate increase anywhere is a strike against health care reform.

10 Jun 2013

Novel abnormalities in FGFR gene identified in a spectrum of cancers

Novel abnormalities in the FGFR gene, called FGFR fusions, were identified in a spectrum of cancers, and preliminary results with cancer cells harboring FGFR fusions suggested that some patients with these cancers may benefit from treatment with FGFR inhibitor drugs, according to data published in Cancer Discovery, a journal of the American Association for Cancer Research.

10 Jun 2013

Genetic testing for cancer-causing mutations in affected families is very low, study finds

A new study of the use of genetic testing for cancer-causing mutations in affected families in France has found that its take-up is very low.

10 Jun 2013

Data emphasise need for comprehensive analysis of mtDNA in mitochondrial disease patients

French scientists have discovered that supposedly rare mutations in the mitochondria, the 'power plants' of human cells responsible for creating energy, account for more than 7% of patients with a mitochondrial disease manifesting itself as a respiratory deficiency.

10 Jun 2013

Scientists discover how Arc protein helps translate learning into memory

Scientists at the Gladstone Institutes have deciphered how a protein called Arc regulates the activity of neurons-providing much-needed clues into the brain's ability to form long-lasting memories. These findings, reported today in Nature Neuroscience, also offer newfound understanding as to what goes on at the molecular level when this process becomes disrupted.

10 Jun 2013

Researchers discover potential target for cancer-fighting drugs

As tumors grow, their centers are squeezed of oxygen. And so tumors must flip specific genetic switches to survive in these hypoxic environments.

10 Jun 2013

Discovery of impaired molecular pathway may help treat children with leukemia

Through genetic engineering of laboratory models, researchers at Dartmouth-Hitchcock Norris Cotton Cancer Center have uncovered a vulnerability in the way cancer cells diverge from normal regenerating cells that may help treat children with leukemia as reported in the journal PNAS on June 3, 2013.

7 Jun 2013

Study: Individuals with ASDs show decrease metabolism of amino acid L-tryptophan

Researchers at the JC Self Research Institute of the Greenwood Genetic Center (GGC), along with collaborators from Biolog, Inc. in California, have reported an important discovery in the understanding of autism which was published this week in Molecular Autism.

7 Jun 2013

Human Argonautes directly cuts messenger RNA

Human Argonautes (hAgo), are key proteins involved in a process known as RNA interference. RNAi, as it is often called, is a mechanism that cells use to regulate gene expression.

7 Jun 2013

Researcher studies mechanism of s-looping to prevent heart abnormalities in infants

Ashok Ramasubramanian, assistant professor of mechanical engineering at Union College, believes that the study of the tiny tubes that make up the embryonic heart offers new hope to babies born with heart abnormalities. So, he's looking to chicken embryos for clues. Ramasubramanian's findings were published in the April 2013 issue of Developmental Dynamics.

7 Jun 2013

Cow antibodies points to new ways for making human medicines

Humans have been raising cows for their meat, hides and milk for millennia. Now it appears that the cow immune system also has something to offer. A new study led by scientists from The Scripps Research Institute (TSRI) focusing on an extraordinary family of cow antibodies points to new ways to make human medicines.

7 Jun 2013

Researchers demonstrate how young genes acquire essential functions

Researchers from UConn and other institutions in the U.S. and abroad have shown how a relatively young gene can acquire a new function and become essential to an organism's life.

7 Jun 2013

Researchers define nine molecular hallmarks of aging, debunk myths related to antioxidants

For some species, living twice as long in good health depends on no more than a few genes. When this fact was revealed by studies on worms three decades ago, it ushered in a golden age of ageing studies that has delivered numerous results, but also sown some confusion.

7 Jun 2013

BioFire Diagnostics' FilmArray Blood Culture Identification Panel receives CE IVD Mark

BioFire Diagnostics, Inc. announced today that it obtained the CE IVD Mark under the European Directive on In Vitro Diagnostic Medical Devices for its FilmArray Blood Culture Identification Panel.

6 Jun 2013

Genes News and Research

Viewpoints: Selling Obamacare in Arizona; 'Hassle-free' marketplace; Seeking the 'grand bargain'

Cytosine methylation plays key role in development of childhood ALL

Researchers receive grant from Arthritis Research UK to study genes associated with hip osteoarthritis

Researchers find master regulator of EMT and metastasis

New technique for identifying mice in breeding colonies

New non-invasive test measures methylation of SDC2 gene, detects 87% of colorectal cancer

Viewpoints: Will 'rate shock' grow?; Krugman says GOP spite is driving opposition to Medicaid expansion; Determining who owns genes

Novel abnormalities in FGFR gene identified in a spectrum of cancers

Genetic testing for cancer-causing mutations in affected families is very low, study finds

Data emphasise need for comprehensive analysis of mtDNA in mitochondrial disease patients

Scientists discover how Arc protein helps translate learning into memory

Researchers discover potential target for cancer-fighting drugs

Discovery of impaired molecular pathway may help treat children with leukemia

Study: Individuals with ASDs show decrease metabolism of amino acid L-tryptophan

Human Argonautes directly cuts messenger RNA

Researcher studies mechanism of s-looping to prevent heart abnormalities in infants

Cow antibodies points to new ways for making human medicines

Researchers demonstrate how young genes acquire essential functions

Researchers define nine molecular hallmarks of aging, debunk myths related to antioxidants

BioFire Diagnostics' FilmArray Blood Culture Identification Panel receives CE IVD Mark

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