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Nanoparticle-programmed immune cells can slow progression of leukemia in mouse model

Researchers at Fred Hutchinson Cancer Research Center have developed biodegradable nanoparticles that can be used to genetically program immune cells to recognize and destroy cancer cells -- while the immune cells are still inside the body.

17 Apr 2017

Vanderbilt geneticists find new way to tap plant pharmacopeia to produce improved therapeutics

Cocaine, nicotine, capsaicin. These are just three familiar examples of the hundreds of thousands of small molecules (also called specialized or secondary metabolites) that plants use as chemical ammunition to protect themselves from predation.

17 Apr 2017

Scientists identify gene responsible for generating key lipid in skin barrier formation

Scientists have identified the gene responsible for generating acylceramide, the key lipid in forming the skin barrier that protects us from pathogens, allergens and other harmful substances. This finding could prove crucial in developing medicines for treating atopic dermatitis and ichthyosis.

17 Apr 2017

Collaboration between Hamilton Robotics and Illumina creates noninvasive streamlined prenatal testing solution

Hamilton Robotics continues to strengthen their ongoing partnership with Illumina, Inc. through the collaborative development of the VeriSeq™ NIPT Solution for high-throughput noninvasive prenatal testing (NIPT).

From Hamilton Process Analytics 14 Apr 2017

Seeing genes inside living cells

For Mazhar Adli, the little glowing dots dancing about on the computer screen are nothing less than the fulfillment of a dream. Those fluorescent dots, moving in real time, are set to illuminate our understanding of the human genome, cancer and other genetic diseases in a way never before possible.

14 Apr 2017

Differences found in cancer occurrence within African and US born blacks

The cancer profile of African-born blacks differs from that of United States-born blacks and varies by region of birth, according to a new study. The study, appearing in CANCER, suggests differences in environmental, cultural, social, and genetic factors, and points to an opportunity to study the risk factors associated with the cancer burden in African-born blacks to help create targeted interventions.

14 Apr 2017

Study finds depression and SUD to be strongest risk factors for prescription opioid overdose

Individuals suffering from a substance use disorder (SUD) or depression are among those at highest risk for a serious prescription opioid overdose, according to a study published in Pain Medicine.

13 Apr 2017

DNA methods can help identify microbial hot spots in buildings

Usually associated with humid and sordid slums, mold is a frequent finding in wealthy homes too. Even the fanciest buildings may harbor hot spots where fungi and other microorganisms subtly proliferate, triggering problems that range from unpleasant smells to severe sickness.

13 Apr 2017

Novo Nordisk introduces new web-based portal that helps patients track their hemophilia treatment

Novo Nordisk today announced the availability of HemaGo™ XChange, a web-based portal that allows people with hemophilia to connect their circle of care to their treatment and bleed information, promoting collaboration and discussion regarding the management of their bleeding disorder.

From Novo Nordisk 13 Apr 2017

Opportunities and risks of direct-to-consumer genetic health risk tests

Accurate genetic testing stands to transform modern medicine by offering effective, personalized treatment.

13 Apr 2017

Researchers correct Duchenne muscular dystrophy using gene-editing alternative

Using the new gene-editing enzyme CRISPR-Cpf1, researchers at UT Southwestern Medical Center have successfully corrected Duchenne muscular dystrophy in human cells and mice in the lab.

13 Apr 2017

International research effort reveals major insights into spread of West African Ebola epidemic

An international effort to analyze the entire database of Ebola virus genomes from the 2013-2016 West African epidemic reveals insights into factors that sped or slowed the rampage and calls for using real-time sequencing and data-sharing to contain future viral disease outbreaks.

12 Apr 2017

Targeted treatment slows progression of two degenerative brain diseases in mice

Scientists report a significant step toward combatting two degenerative brain diseases that chip away at an individual's ability to move, and think.

12 Apr 2017

TSRI study could lead to personalized treatments for alcohol dependence

A new study led by scientists at The Scripps Research Institute could help researchers develop personalized treatments for alcoholism and alcohol use disorder.

12 Apr 2017

Gladstone scientists discover common mechanism that links neurodegeneration in young and old

Scientists at the Gladstone Institutes and the University of California, San Francisco (UCSF), identified a common mechanism in two forms of neurodegeneration that affect young adults or the elderly.

12 Apr 2017

'Human knockouts': Genetics in families reveals basic biology and possible therapeutics for disorders

More than 1,800 individuals carrying loss-of-function mutations in both copies of their genes, so-called "human knockouts," are described in the first major study to be published in Nature this week by an international collaboration led by the Perelman School of Medicine at the University of Pennsylvania and colleagues.

12 Apr 2017

Scientists discover potential trigger for MDS in children with rare genetic disorder

Myelodysplastic syndrome is an umbrella term used to describe disorders characterized by the bone marrow's inability to produce normal blood cells.

12 Apr 2017

Developmental Split-Brain syndrome discovery

Our group describes a new entity, which we refer to as “Developmental Split-Brain syndrome” which we discovered affected four individuals from three unrelated families. All affected individuals showed disruption of communicating tracts between the right and left side of the brain which meant that there is lack of coordination and communication between the two sides of the brain.

12 Apr 2017

Study shows new prospects for understanding mechanisms underlying vision

New approaches to the study of vision both from the neurobiological perspective and with a view to the technological development of artificial vision systems: that is the key result of the research project conducted by SISSA in Trieste in collaboration with the Istituto Italiano di Tecnologia in Rovereto and published in the science journal eLife.

12 Apr 2017

Researchers identify three novel genetic mutations linked to Fuchs dystrophy

Researchers discovered three novel genetic mutations associated with Fuchs endothelial corneal dystrophy, the most common corneal disorder requiring transplantation.

12 Apr 2017

Genetic News and Research

Nanoparticle-programmed immune cells can slow progression of leukemia in mouse model

Vanderbilt geneticists find new way to tap plant pharmacopeia to produce improved therapeutics

Scientists identify gene responsible for generating key lipid in skin barrier formation

Collaboration between Hamilton Robotics and Illumina creates noninvasive streamlined prenatal testing solution

Seeing genes inside living cells

Differences found in cancer occurrence within African and US born blacks

Study finds depression and SUD to be strongest risk factors for prescription opioid overdose

DNA methods can help identify microbial hot spots in buildings

Novo Nordisk introduces new web-based portal that helps patients track their hemophilia treatment

Opportunities and risks of direct-to-consumer genetic health risk tests

Researchers correct Duchenne muscular dystrophy using gene-editing alternative

International research effort reveals major insights into spread of West African Ebola epidemic

Targeted treatment slows progression of two degenerative brain diseases in mice

TSRI study could lead to personalized treatments for alcohol dependence

Gladstone scientists discover common mechanism that links neurodegeneration in young and old

'Human knockouts': Genetics in families reveals basic biology and possible therapeutics for disorders

Scientists discover potential trigger for MDS in children with rare genetic disorder

Developmental Split-Brain syndrome discovery

Study shows new prospects for understanding mechanisms underlying vision

Researchers identify three novel genetic mutations linked to Fuchs dystrophy

eBook: Using iPSCs models for human disease research and drug discovery eBook

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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