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New process separates beneficial glucocorticoids from unwanted side-effects

A collaboration led by Scripps Research has developed a way to separate the beneficial anti-inflammatory properties of a group of steroids called glucocorticoids from some of their unwanted side-effects, through an optimization process they named "ligand class analysis."

3 Feb 2021

Delayed time between abnormal stool-based screening and colonoscopy increases cancer risk

Colorectal cancer is the second most common cause of cancer-related mortality among men and women in the United States, according to the American Cancer Society. At-home tests, which measure blood in stool as a potential marker for colon cancer, are often used for colorectal cancer screening.

3 Feb 2021

Single-dose vaccination effective for healthcare workers with prior SARS-CoV-2 infection

The findings reveal that healthcare workers previously infected with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) develop significantly higher antibody titers in response to a single dose of COVID-19 vaccine, as compared to healthcare workers without prior SARS-CoV-s infection. The study is currently available on the medRxiv* preprint server.

2 Feb 2021

Study shows accuracy of dried blood spot testing for detection of CMV infection in newborns

In Minnesota, there are currently about 60 diseases that all newborns are screened for at birth using a heel prick and a few drops of blood.

2 Feb 2021

Researchers find possible cause for self-destructive immune system attacks in autoimmune diseases

Autoimmune diseases, in which the body's own immune system attacks healthy tissue, can be life-threatening and can impact all organs.

2 Feb 2021

ECMO life-support therapy can increase odds of survival for critically-ill COVID-19 patients

COVID-19 has caused more than 2 million deaths worldwide since the World Health Organization declared it a pandemic in March 2020.

2 Feb 2021

Researchers develop rapid COVID-19 diagnostic test affordable for low-income families

A test that detects antibodies to the novel coronavirus in 10 minutes and costs only a fifth of the market average has been developed by researchers at the University of São Paulo's São Carlos Chemistry Institute and Brazilian startup Biolinker, with São Paulo Research Foundation - FAPESP's support.

2 Feb 2021

MIT engineers design origami-inspired medical patch for minimally invasive tissue sealing

Many surgeries today are performed via minimally invasive procedures, in which a small incision is made and miniature cameras and surgical tools are threaded through the body to remove tumors and repair damaged tissues and organs.

2 Feb 2021

Immune dysregulation can affect the efficacy of CAR T therapy in some lymphoma patients

Chimeric antigen receptor T-cell therapy, or CAR T, has been a breakthrough in the treatment of blood cancers such as acute lymphoblastic leukemia and diffuse large B-cell lymphoma.

2 Feb 2021

Study finds increased opioid consumption two years after intensive care

Nearly 11 percent of people admitted to an intensive care unit in Sweden between 2010 and 2018 received opioid prescriptions on a regular basis for at least six months and up to two years after discharge.

2 Feb 2021

Simple soil remediation can save children from lead toxicity

Simple soil remediation can substantially reduce levels of the toxic metal lead in the blood of children living in heavily contaminated areas, says a new study conducted in Bangladesh.

2 Feb 2021

Scientists discover potential drug target for Hutchinson-Gilford progeria syndrome

New study describes a potential drug target for Hutchinson-Gilford progeria syndrome that may aid in the development of more effective treatments.

2 Feb 2021

Study shows link between periodontitis and COVID-19 complications

COVID-19 patients are at least three times more likely to experience complications if they also have gum disease, according to research published today in the Journal of Clinical Periodontology, the official publication of the European Federation of Periodontology.

2 Feb 2021

Delaying colonoscopy after an abnormal stool test can have major consequences

A new Veterans Affairs study finds that delays in undergoing colonoscopy following an abnormal stool test increase the risk of a colorectal cancer diagnosis and cancer-related death.

2 Feb 2021

Study shows safety and effectiveness of two recommended ICU sedatives

Sedative medications used in intensive care are associated with increased delirium, which is in turn connected with higher medical costs and greater risk of death and ICU-related dementia.

2 Feb 2021

Young, Black patients at higher risk of death in the first year after a heart transplant

Young, Black adults are more than twice as likely to die in the first year after a heart transplant when compared to same-age, non-Black heart transplant recipients, according to new research published today in Circulation: Heart Failure, an American Heart Association journal.

2 Feb 2021

Albumin: The Natural Choice for Diagnostic Tests

The availability of established diagnostic kits has enabled researchers to plug-and-play in the design of COVID-19 diagnostics. Such technologies took decades to optimize, but they are now playing an important role in identifying and managing the spread of COVID-19. Recombumin® provides an enhanced solution as part of this toolbox for dealing with this disease

From Albumedix Ltd. 2 Feb 2021

Elevated ACE2 and inflammation levels increase risk for pregnant women infected with SARS-CoV-2

Among the hundred million or so cases of coronavirus disease 2019 (COVID-19) that have occurred since the pandemic began, pregnant women have been a conspicuous risk group. However, the exact nature of the risk they and their fetuses face, and the mechanism by which it operates, is far from clear.

2 Feb 2021

Study explores merits and risks of bariatric surgery in younger teens

Obesity and its duration are significant risk factors for type 2 diabetes, cardiovascular events, multiple cancers, and decreased quality of life. According to the Centers for Disease Control and Prevention, obesity affects 20.6% of adolescents ages 12-19 in the United States, meaning a potential lifetime of dealing with this condition.

2 Feb 2021

Intensive BP lowering reduces cardiovascular risk in patients exposed to air pollution

Evidence suggests particulate matter is the air pollutant which poses the greatest threat to global health. Studies have shown that exposure to particulate matter smaller than 2.5 microns is associated with acute and chronic elevations in blood pressure (BP) as well as hypertension.

2 Feb 2021

Blood News and Research

New process separates beneficial glucocorticoids from unwanted side-effects

Delayed time between abnormal stool-based screening and colonoscopy increases cancer risk

Single-dose vaccination effective for healthcare workers with prior SARS-CoV-2 infection

Study shows accuracy of dried blood spot testing for detection of CMV infection in newborns

Researchers find possible cause for self-destructive immune system attacks in autoimmune diseases

ECMO life-support therapy can increase odds of survival for critically-ill COVID-19 patients

Researchers develop rapid COVID-19 diagnostic test affordable for low-income families

MIT engineers design origami-inspired medical patch for minimally invasive tissue sealing

Immune dysregulation can affect the efficacy of CAR T therapy in some lymphoma patients

Study finds increased opioid consumption two years after intensive care

Simple soil remediation can save children from lead toxicity

Scientists discover potential drug target for Hutchinson-Gilford progeria syndrome

Study shows link between periodontitis and COVID-19 complications

Delaying colonoscopy after an abnormal stool test can have major consequences

Study shows safety and effectiveness of two recommended ICU sedatives

Young, Black patients at higher risk of death in the first year after a heart transplant

Albumin: The Natural Choice for Diagnostic Tests

Elevated ACE2 and inflammation levels increase risk for pregnant women infected with SARS-CoV-2

Study explores merits and risks of bariatric surgery in younger teens

Intensive BP lowering reduces cardiovascular risk in patients exposed to air pollution

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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