Bone Marrow News and Research

RSS

Bone Marrow is the soft, sponge-like tissue in the center of most bones. It produces white blood cells, red blood cells, and platelets.

Early treatment with stem cells can safely help recovery in stroke patients, study shows

A multicenter trial looking at whether a single dose of millions of adult, bone-marrow-derived stem cells can aid stroke recovery indicates it's safe and well-tolerated by patients but may not significantly improve their recovery within the first three months, researchers report.

20 Mar 2017

Combination therapy that targets immune-busting cells effective in treating advanced prostate cancer

Advanced prostate cancer resistant to castration therapy appears to respond well to a combination of immune checkpoint blockades and treatments that target certain immune-busting cells commonly associated with poor patient prognosis and therapy resistance.

10 Mar 2017

Drug could activate innate anti-tumor immunity to eradicate aggressive prostate cancer in mice

Cabozantinib, a drug already used to treat patients with certain types of thyroid or kidney cancer, was able to eradicate invasive prostate cancers in mice by causing tumor cells to secrete factors that entice neutrophils - the first-responders of the immune system - to infiltrate the tumor, where they triggered an immune response that led to tumor clearance.

9 Mar 2017

Common cold virus can cause deadly pneumonia in transplant patients, study shows

The common cold is a major source of annoyance for most of us, but new research has found that the most prevalent respiratory infection can be far worse than a stuffy nose for one sector of the population — bone marrow transplant patients.

8 Mar 2017

Researchers reveal potential health risks of deep space travel

Sending a manned mission to Mars requires more than a powerful launch rocket. Prep work also includes learning how a three-year space flight could affect the human body.

8 Mar 2017

Clinical study seeks to examine new combination therapy for treating AML patients

A pair of drugs that may be a one-two punch needed to help combat acute myeloid leukemia (AML), an aggressive blood cancer that kills nearly three-fourths of patients within five years of diagnosis, is the focus of a new multi-center clinical trial that will enroll patients at three sites across the U.S.

7 Mar 2017

New treatment option could provide effective therapy for patients with dermatologic conditions

Alopecia areata, atopic dermatitis and vitiligo are highly visible dermatologic conditions that can have a negative effect on patients' quality of life and overall health. An emerging treatment option, however, could provide effective therapy for patients with these conditions.

3 Mar 2017

Scientists propose rejuvenating bone marrow stem cell niche to boost immunity, fend off cancers

As people get older so do the hematopoietic stem cells (HSCs) that form their blood, creating an increased risk for compromised immunity and certain blood cancers. Now researchers are reporting in the scientific journal that the bone marrow niche where HSC's form also ages, contributing to the problem.

3 Mar 2017

City of Hope researchers find how HER2-positive breast cancer patients develop brain metastases

Ninety percent of cancer deaths are from cancer spread. Breast cancer patients, for example, typically do not die because cancer returns in their breast, they die because it spreads to other parts of their body. The most dangerous of which is the brain.

2 Mar 2017

Innovative gene therapy allows complete remission of clinical signs of sickle cell disease

A team led by Pr. Marina Cavazzana conducted at Necker Children's Hospital, AP-HP and the Imagine Institute in October 2014 gene therapy in the context of a phase I clinical trial / II in a patient 13 years with severe sickle cell disease.

2 Mar 2017

Study establishes ENL protein as potential drug target for acute myeloid leukemia

Anyone who uses an employee badge to enter a building may understand how a protein called ENL opens new possibilities for treating acute myeloid leukemia (AML), a fast-growing cancer of bone marrow and blood cells and the second most common type of leukemia in children and adults.

2 Mar 2017

Researchers looking at ways to target lingering cancer stem cells that cause disease relapse

Chemotherapy treatment targets and kills cancer cells in the body. However, even after treatment, some cancer cells may remain in the patient's system undetected.

2 Mar 2017

UNC Lineberger achieves major milestone with launch of cellular immunotherapy program

University of North Carolina Lineberger Comprehensive Cancer Center researchers have achieved a major milestone with the launch of two clinical trials testing an experimental therapy in which patients' own immune cells are genetically engineered to fight their cancer.

1 Mar 2017

Researchers justify alternative theory about cause of type 1 diabetes

An international team of researchers led by City of Hope's Bart Roep, Ph.D., the Chan Soon-Shiong Shapiro Distinguished Chair in Diabetes and professor/founding chair of the Department of Diabetes Immunology, has been able to justify an alternative theory about the cause of type 1 diabetes (T1D) through experimental work.

28 Feb 2017

Fat stem cells may be preferred type for use in therapeutic applications, study shows

An international team of researchers, funded by Morris Animal Foundation, has shown that adipose (fat) stem cells might be the preferred stem cell type for use in canine therapeutic applications, including orthopedic diseases and injury.

27 Feb 2017

Fred Hutch scientists make important step in identifying specific T cells to fight against cancer

A new discovery by researchers at the Fred Hutchinson Cancer Research Center in Seattle makes an important step in identifying which specific T cells within the diverse army of a person's immune system are best suited to fight cancer.

25 Feb 2017

Novel antiviral drug can protect transplant patients against CMV infections

In a significant advance in improving the safety of donor stem cell transplants, a major clinical trial led by researchers at Dana-Farber Cancer Institute and Brigham and Women's Hospital has shown that a novel agent can protect against the most common viral infection that patients face after transplantation.

24 Feb 2017

Scientists propose potential new treatment for Gaucher disease

Scientists propose in Nature blocking a molecule that drives inflammation and organ damage in Gaucher and maybe other lysosomal storage diseases as a possible treatment with fewer risks and lower costs than current therapies.

23 Feb 2017

Research: Biomaterials that mimic bone marrow can alter blood cell development

Researchers at the University of Illinois report they can alter blood cell development through the use of biomaterials designed to mimic characteristics of the bone marrow.

23 Feb 2017

Penn-led researchers gain better understanding of how T cells support long-lived plasma cells

If you've ever wondered how a vaccine given decades ago can still protect against infection, you have your plasma cells to thank. Plasma cells are long-lived B cells that reside in the bone marrow and churn out antibodies against previously encountered vaccines or pathogens.

22 Feb 2017

Bone Marrow News and Research

Further Reading

Early treatment with stem cells can safely help recovery in stroke patients, study shows

Combination therapy that targets immune-busting cells effective in treating advanced prostate cancer

Drug could activate innate anti-tumor immunity to eradicate aggressive prostate cancer in mice

Common cold virus can cause deadly pneumonia in transplant patients, study shows

Researchers reveal potential health risks of deep space travel

Clinical study seeks to examine new combination therapy for treating AML patients

New treatment option could provide effective therapy for patients with dermatologic conditions

Scientists propose rejuvenating bone marrow stem cell niche to boost immunity, fend off cancers

City of Hope researchers find how HER2-positive breast cancer patients develop brain metastases

Innovative gene therapy allows complete remission of clinical signs of sickle cell disease

Study establishes ENL protein as potential drug target for acute myeloid leukemia

Researchers looking at ways to target lingering cancer stem cells that cause disease relapse

UNC Lineberger achieves major milestone with launch of cellular immunotherapy program

Researchers justify alternative theory about cause of type 1 diabetes

Fat stem cells may be preferred type for use in therapeutic applications, study shows

Fred Hutch scientists make important step in identifying specific T cells to fight against cancer

Novel antiviral drug can protect transplant patients against CMV infections

Scientists propose potential new treatment for Gaucher disease

Research: Biomaterials that mimic bone marrow can alter blood cell development

Penn-led researchers gain better understanding of how T cells support long-lived plasma cells

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Latest News