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Lenvatinib trial offers hope for thyroid cancer patients

A new targeted therapy called lenvatinib has been shown to improve progression-free survival among patients with advanced thyroid cancer that is not responsive to iodine-131.

13 Feb 2015

$Lenvatinib therapy improves survival in patients with advanced radioiodine-refractory thyroid cancer$

Lenvatinib therapy improves survival in patients with advanced radioiodine-refractory thyroid cancer

In a pivotal Phase III study led by researchers at The University of Texas MD Anderson Cancer Center, the oral anti-angiogenic therapy lenvatinib has shown dramatic improvement in progression-free survival in patients with advanced radioiodine-refractory thyroid cancer.

12 Feb 2015

ATA recommends daily serving of iodine in multivitamin/mineral supplements for pregnant, breastfeeding women

The American Thyroid Association has championed the effort to include a daily serving of iodine in multivitamin/mineral supplements intended for pregnant and breastfeeding women, and it applauds the new guidelines released by the U.S. Council for Responsible Nutrition advising manufacturers to include 150 micrograms of iodine to these daily supplements.

11 Feb 2015

Jefferson, RMA of Philadelphia announce clinical partnership

Jefferson announced today its clinical partnership with RMA of Philadelphia, merging the expertise of two outstanding groups of reproductive specialists on its Center City campus.

11 Feb 2015

Short nap can reverse hormonal impact of poor night's sleep

A short nap can help relieve stress and bolster the immune systems of men who slept only two hours the previous night, according to a new study published in the Endocrine Society's Journal of Clinical Endocrinology & Metabolism.

11 Feb 2015

Study shows link between low vitamin D levels in childhood and occurrence of atherosclerosis in adulthood

Low levels of 25-OH vitamin D in childhood were associated with subclinical atherosclerosis over 25 years later in adulthood, according to a new study published in the Endocrine Society's Journal of Clinical Endocrinology & Metabolism.

11 Feb 2015

Chiasma announces publication of octreotide capsules Phase III study results in JCEM

Chiasma Inc., a U.S. privately-held biopharma company, announced today that results from a multicenter Phase III study of the investigational new drug, octreotide capsules, were published online for early release on Feb. 9, ahead of print, by the Journal of Clinical Endocrinology & Metabolism.

10 Feb 2015

Diplomat to dispense FDA-approved IBRANCE (palbociclib) to treat metastatic breast cancer

Diplomat Pharmacy, Inc., the nation's largest independent specialty pharmacy, announced today it will dispense Pfizer's new breakthrough medication, IBRANCE (palbociclib), starting tomorrow, Feb. 5.

4 Feb 2015

Many MEN1 tumour types found in children

Most tumour types reported in adult patients with multiple endocrine neoplasia Type-1 can be found in children with the condition, although rarely before the age of 10 years, shows a large study.

30 Jan 2015

Day-to-day chemical exposures linked to earlier menopause

Women whose bodies have high levels of chemicals found in plastics, personal-care products, common household items and the environment experience menopause two to four years earlier than women with lower levels of these chemicals, according to a new study at Washington University School of Medicine in St. Louis.

29 Jan 2015

Thyroid disease can affect woman's reproductive health

Thyroid disease can have significant effects on a woman's reproductive health and screening for women presenting with fertility problems and recurrent early pregnancy loss should be considered, suggests a new review published today (23 January) in The Obstetrician & Gynaecologist.

23 Jan 2015

Study finds relationship between menopausal symptoms, bone health in postmenopausal women

The first large prospective cohort study to examine the relationship between menopausal symptoms and bone health in postmenopausal women has found that those who experience moderate to severe hot flashes and night sweats during menopause tend to have lower bone mineral density and higher rates of hip fracture than peers with no menopausal symptoms.

23 Jan 2015

Study: Mutated ATRX gene may serve as much-needed biomarker for rare neuroendocrine tumors

A somatic mutation in the ATRX gene has recently been shown as a potential molecular marker for aggressive brain tumors, such as gliomas, neuroblastomas and pancreatic neuroendocrine tumors. Now, for the first time, researchers at Penn's Abramson Cancer Center have found that the same mutated gene may serve as a much-needed biomarker for the pheochromocytomas and paragangliomas (PCC/PGL) that become malignant.

21 Jan 2015

Researchers find genetic mutation that causes glycogen storage disease type IIIa in Inuit

A team of Canadian and Japanese researchers has identified the genetic mutation responsible for glycogen storage disease type IIIa in Inuit in northern Quebec, Canada, in a study published in CMAJ (Canadian Medical Association Journal).

20 Jan 2015

Endocrine Society issues guideline on prescribing drugs to manage obesity, promote weight loss

The Endocrine Society today issued a Clinical Practice Guideline (CPG) on strategies for prescribing drugs to manage obesity and promote weight loss.

16 Jan 2015

Scientists identify first genetic marker linked to severe neurological toxicity

Paclitaxel is a chemotherapeutic drug that has been shown to be highly effective when treating solid tumours, such as breast, ovarian and lung tumours. However, its use frequently causes peripheral neuropathies, neurological problems that affect the vast majority of patients.

15 Jan 2015

High vitamin D levels boost survival for metastatic colorectal cancer patients

According to a new study led by researchers at Dana-Farber Cancer Institute, clinical trial patients with metastatic colorectal cancer who had high levels of vitamin D in their bloodstream prior to treatment with chemotherapy and targeted drugs, survived longer, on average, than patients with lower levels of the vitamin.

14 Jan 2015

Study finds difference between results from IHC and quantitative molecular techniques

The cause of type 1 diabetes remains unknown. Several studies using immunohistochemistry (IHC) have independently reported hyperexpression of human leukocyte antigen (HLA) class I on pancreatic islet cells in young patients with recent-onset type 1 diabetes. Investigators have therefore suggested that HLA hyperexpression may be an important first step in the development of type 1 diabetes.

12 Jan 2015

Vitamin B counteracts levels of DDT in women who are more likely to get, stay pregnant

Women who have adequate levels of B vitamins in their bodies are more likely to get and stay pregnant even when they also have high levels of a common pesticide known to have detrimental reproductive effects, according to new Johns Hopkins Bloomberg School of Public Health research.

5 Jan 2015

Whole-genome sequencing can identify patients' risk for hereditary cancer

UT Southwestern Medical Center cancer researchers have demonstrated that whole-genome sequencing can be used to identify patients' risk for hereditary cancer, which can potentially lead to improvements in cancer prevention, diagnosis, and care.

24 Dec 2014

Endocrine News and Research

Lenvatinib trial offers hope for thyroid cancer patients

Lenvatinib therapy improves survival in patients with advanced radioiodine-refractory thyroid cancer

ATA recommends daily serving of iodine in multivitamin/mineral supplements for pregnant, breastfeeding women

Jefferson, RMA of Philadelphia announce clinical partnership

Short nap can reverse hormonal impact of poor night's sleep

Study shows link between low vitamin D levels in childhood and occurrence of atherosclerosis in adulthood

Chiasma announces publication of octreotide capsules Phase III study results in JCEM

Diplomat to dispense FDA-approved IBRANCE (palbociclib) to treat metastatic breast cancer

Many MEN1 tumour types found in children

Day-to-day chemical exposures linked to earlier menopause

Thyroid disease can affect woman's reproductive health

Study finds relationship between menopausal symptoms, bone health in postmenopausal women

Study: Mutated ATRX gene may serve as much-needed biomarker for rare neuroendocrine tumors

Researchers find genetic mutation that causes glycogen storage disease type IIIa in Inuit

Endocrine Society issues guideline on prescribing drugs to manage obesity, promote weight loss

Scientists identify first genetic marker linked to severe neurological toxicity

High vitamin D levels boost survival for metastatic colorectal cancer patients

Study finds difference between results from IHC and quantitative molecular techniques

Vitamin B counteracts levels of DDT in women who are more likely to get, stay pregnant

Whole-genome sequencing can identify patients' risk for hereditary cancer

Improving healthcare sustainability through carbon data

Managing vibration in IVF laboratories

A New Approach to Preventing Bladder Cancer Recurrence

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