Genetic News and Research

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Study forces a textbook rewrite on cell division

Scientists at the Ruđer Bošković Institute (RBI) in Zagreb, Croatia, have discovered that the protein CENP-E, long believed to act as a motor dragging chromosomes into place during cell division, in fact plays a completely different role in chromosome movement.

22 Oct 2025

Researchers gain new insights into aging based on studies in dogs

Lab-based studies have provided lots of information on the biology of aging, but it's unclear how lab discoveries apply to aging in the real world. Research in Aging Cell provides insights into aging based on studies in dogs.

22 Oct 2025

People with multiple sclerosis found to have dysbiotic oral microbiome

With ads everywhere for pro- or pre-biotic foods and supplements, most people are familiar with the gut microbiome-the trillions of bacteria, fungi, and viruses that colonize our digestive tract-and the idea that keeping our gut microbiome healthy improves our overall health.

22 Oct 2025

New technology can track beneficial bacteria after fecal microbiota transplants

Researchers at the Icahn School of Medicine at Mount Sinai and their collaborators have developed a new technology to track beneficial bacteria after fecal microbiota transplants (FMT).

22 Oct 2025

AI algorithm proves more accurate than experts in glaucoma detection

While artificial intelligence (AI)-powered screening has been validated for diabetic retinopathy, applying the technology to glaucoma has proved more challenging because glaucoma is not one disease. A glaucoma diagnosis is based on a constellation of symptoms, diagnostic tests, and longitudinal data.

22 Oct 2025

Discovery offers a breakthrough approach to combat prostate tumor growth

Prostate cancer relies on genetic "switches", called enhancers, that can turn on tumor-promoting genes.

22 Oct 2025

Epigenetic editing enables safer and more effective T cell therapies

Arc Institute, Gladstone Institutes, and University of California, San Francisco, scientists have developed an epigenetic editing platform that enables safe modification of multiple genes in primary human T cells, addressing a key manufacturing and scalability challenge in next-generation cell therapies.

21 Oct 2025

Researchers develop a novel approach to monitor CD8⁺ T cell activity over time

The ability of immune cells-particularly CD8+ T cells-to launch a rapid burst of proliferation inside tumors is key to the success of modern day cancer immunotherapies.

21 Oct 2025

Genetic inflammatory signature defines depression subtypes and treatment response

Researchers led by Prof. Alessandro Serretti at Kore University of Enna have identified a genetic inflammatory signature that defines specific depression subtypes and influences how patients respond to antidepressant medications, according to new peer-reviewed research published today in Genomic Psychiatry.

21 Oct 2025

New AI-driven approach identifies treatments to reprogram and destroy cancer stem cells

Scientists at University of California San Diego have developed a new approach to destroying cancer stem cells – hard-to-find cells that help cancers spread, come back after treatment and resist therapy.

21 Oct 2025

Researchers develop a new approach for treating children with neuroblastoma

A research team from the University of Zurich and the University Children's Hospital Zurich has developed a new approach for treating children with malignant tumors of the nervous system.

21 Oct 2025

Study provides a new approach for the treatment of prostate tumors

An international research team led by the Medical University of Vienna has demonstrated for the first time that thyroid hormone plays a key role in the development and progression of prostate cancer.

21 Oct 2025

Molecular evidence connects higher childhood cognitive function to longer lifespan

Researchers led by Dr. W. David Hill at the University of Edinburgh have identified a significant genetic correlation between childhood cognitive function and longevity, providing the first molecular genetic evidence that intelligence measured in youth shares genetic factors with lifespan.

21 Oct 2025

Genetic and inflammatory factors amplify the link between earlier menopause and cognitive risk

Women are significantly more likely than men to develop Alzheimer's disease. Earlier age at menopause is associated with a greater risk for late-life cognitive decline and Alzheimer's disease.

21 Oct 2025

Low-calorie diets linked to higher psoriatic arthritis risk, genetic study suggests

This Mendelian randomization study found that low-calorie diets may slightly increase the risk of psoriatic arthritis, while vegetarian and gluten-free diets showed no causal links to psoriasis, acne, or atopic dermatitis. The findings challenge assumptions about universally beneficial dietary patterns and highlight the need for cautious interpretation of dietary interventions in inflammatory skin disease.

19 Oct 2025

MRI age clocks reveal how each organ ages differently and predict who develops disease or lives longer

Researchers developed seven MRI-based biological age clocks across major organs using UK Biobank imaging, linking each to proteins, metabolites, genetics, disease risks, mortality, and cognitive decline. These organ-specific age gaps reveal how uneven aging shapes vulnerability to conditions such as diabetes, hypertension, and dementia, opening new paths for precision prevention and clinical trial stratification

19 Oct 2025

Belzutifan demonstrates strong clinical activity in two rare neuroendocrine tumors

A multicenter Phase II clinical trial led by researchers at The University of Texas MD Anderson Cancer Center demonstrated significant tumor shrinkage and disease control in patients with advanced pheochromocytoma and paraganglioma (PPGL), two rare and potentially life-threatening neuroendocrine tumors.

18 Oct 2025

Study reveals how a microglial mutation increases risk for Alzheimer's disease

Dominika Pilat, PhD, and Ana Griciuc, PhD, of the Department of Neurology at Massachusetts General Hospital are the lead and senior authors of a paper published in Neuron, "The Gain-of-Function TREM2-T96K Mutation Increases Risk for Alzheimer's Disease by Impairing Microglial Function."

17 Oct 2025

Researchers achieve proof of concept for generating eggs from somatic cells

Researchers at Oregon Health & Science University have accomplished a unique proof of concept to treat infertility by turning skin cells into eggs capable of producing early human embryos.

17 Oct 2025

Review reveals how paternal lifestyle shapes sperm epigenetics and offspring health

A new review in Clinical Epigenetics synthesises growing evidence that paternal lifestyle and environmental exposures such as diet, obesity, smoking, endocrine-disrupting chemicals, and stress alter sperm epigenetic marks (DNA methylation, histone retention, and small non-coding RNAs).

17 Oct 2025

Genetic News and Research

Study forces a textbook rewrite on cell division

Researchers gain new insights into aging based on studies in dogs

People with multiple sclerosis found to have dysbiotic oral microbiome

New technology can track beneficial bacteria after fecal microbiota transplants

AI algorithm proves more accurate than experts in glaucoma detection

Discovery offers a breakthrough approach to combat prostate tumor growth

Epigenetic editing enables safer and more effective T cell therapies

Researchers develop a novel approach to monitor CD8⁺ T cell activity over time

Genetic inflammatory signature defines depression subtypes and treatment response

New AI-driven approach identifies treatments to reprogram and destroy cancer stem cells

Researchers develop a new approach for treating children with neuroblastoma

Study provides a new approach for the treatment of prostate tumors

Molecular evidence connects higher childhood cognitive function to longer lifespan

Genetic and inflammatory factors amplify the link between earlier menopause and cognitive risk

Low-calorie diets linked to higher psoriatic arthritis risk, genetic study suggests

MRI age clocks reveal how each organ ages differently and predict who develops disease or lives longer

Belzutifan demonstrates strong clinical activity in two rare neuroendocrine tumors

Study reveals how a microglial mutation increases risk for Alzheimer's disease

Researchers achieve proof of concept for generating eggs from somatic cells

Review reveals how paternal lifestyle shapes sperm epigenetics and offspring health

eBook: Using iPSCs models for human disease research and drug discovery eBook

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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