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Single antibody causes a rare but dangerous reaction to widely-used blood thinner

Researchers at McMaster University have discovered that a rare but dangerous reaction to a widely used blood thinner is caused by a single antibody – overturning decades of medical misunderstanding and opening the door to more precise ways of diagnosing and treating this medical complication.

3 Sep 2025

Apple juice has temporary effects on saliva but no lasting damage

A new study led by the University of Portsmouth suggests our saliva is stronger than we thought.

3 Sep 2025

Sacubitril/valsartan shows benefit over enalapril in heart failure caused by Chagas disease

In patients with heart failure (HF) caused by Chagas disease, sacubitril/valsartan was superior to enalapril for the composite primary endpoint, predominantly driven by a significant reduction in N-terminal pro-B-type natriuretic peptide (NT-proBNP), according to late-breaking research presented in a Hot Line session today at ESC Congress 2025.

3 Sep 2025

No clear benefit from surgical left atrial appendage occlusion in non-AF patients after valve surgery

No benefit in terms of prevention of ischemic stroke, transient ischemic attack and cardiovascular mortality after 1 year was observed when surgical left atrial appendage occlusion was performed in high-risk non-atrial fibrillation patients after valvular surgery, according to late-breaking research presented in a Hot Line session today at ESC Congress 2025.

3 Sep 2025

Long-term benzodiazepine use linked to poor sleep quality in older adults

Long-term use of benzodiazepine and related drugs has been linked to poorer quality sleep in older adults with insomnia.

3 Sep 2025

Novel vascularized cancer-on-a-chip model reflects the microenvironment of liver tumors

Dr. Vadim Jucaud's lab at the Terasaki Institute has developed a human vascularized liver cancer-on-a-chip model to evaluate vessel remodeling and cell death in response to embolic agents.

3 Sep 2025

First complete brain activity map reveals how decisions are made

The first complete activity map of the brain has been unveiled by a large international collaboration of neuroscientists.

3 Sep 2025

Intravenous cangrelor provides rapid platelet inhibition in cardiogenic shock

Compared with crushed ticagrelor, intravenous cangrelor provided immediate, effective platelet inhibition, with no increase in major bleeding and lower mortality rates in patients with acute myocardial infarction and cardiogenic shock, according to late-breaking research presented in a Hot Line session today at ESC Congress 2025.

3 Sep 2025

Hepatitis B immunity reduces diabetes risk across age groups

New research to be presented at this year's Annual Meeting of the European Association for the Study of Diabetes (EASD) in Vienna, Austria (15-19 September) and published in the journal Diagnostics shows that people with hepatitis B immunity induced by vaccination have a lower risk of developing diabetes of any kind.

2 Sep 2025

Urine test identifies three biomarkers for accurate prostate cancer detection

Researchers at the Johns Hopkins Kimmel Cancer Center, Johns Hopkins All Children's Hospital and four other institutions have devised a novel method to test for prostate cancer using biomarkers present in urine, funded in part by the National Institutes of Health.

2 Sep 2025

AI scans arteries and predicts risk after heart attack better than traditional review

Researchers found that AI applied to OCT imaging can standardize detection of thin-cap fibroatheroma (TCFA) and identify post–heart attack patients at higher two-year risk. Whole-segment AI analysis outperformed lesion-focused human review, offering stronger prognostic value and reassurance for low-risk patients.

2 Sep 2025

Breakthrough discovery reveals treatable form of familial mesothelioma

Researchers working independently at the University of Hawaii Cancer Center and the National Cancer Institute have discovered, and validated, a new variant of mesothelioma that may lead to more successful treatments.

2 Sep 2025

Electrical stimulation reprograms macrophages to reduce inflammation

Scientists from Trinity College Dublin have discovered that electrically stimulating "macrophages" – one of the immune systems key players – can "reprogramme" them in such a way to reduce inflammation and encourage faster, more effective healing in disease and injury.

2 Sep 2025

Plant-derived carotenoid found to boost immune response against cancer

In a new study, researchers from the University of Chicago discovered that zeaxanthin, a plant-derived carotenoid best known for protecting vision, may also act as an immune-boosting compound by strengthening the cancer-fighting activity of immune cells.

2 Sep 2025

Heparanase 2 emerges as key protector of blood vessel integrity

An international research team led by MDI Biological Laboratory President Hermann Haller, M.D. and postdoctoral researcher Yannic Becker, Ph.D. has discovered that a little-known molecule, heparanase 2 (Hpa2), plays a critical role in maintaining blood vessels' integrity.

2 Sep 2025

New neurochemical signature distinguishes Parkinson’s disease from essential tremor

Researchers have identified a neurochemical signature that sets Parkinson's disease apart from essential tremor - two of the most common movement disorders, but each linked to distinct changes in the brain.

2 Sep 2025

AI model predicts flu vaccine strains more accurately than WHO

AI-based models like VaxSeer outperform traditional methods in flu vaccine strain selection, enhancing effectiveness and addressing global influenza challenges.

2 Sep 2025

Study urges significant investment in cancer research in poorer nations

Researchers at the University of Southampton, examining worldwide variations in funding for cancer research, say there's a pressing need to invest more in lower-income countries.

2 Sep 2025

Can honey protect your brain? Study reviews its potential against Alzheimer's

This review examined 27 preclinical studies on honey and Alzheimer’s disease, showing honey’s bioactive compounds counter oxidative stress, inflammation, and amyloid buildup. Despite promising lab results, no human trials exist, underscoring the need for clinical research.

1 Sep 2025

Scientists discover molecular brake that limits T cell attack on tumors

In a discovery that could expand the array of current cancer immunotherapy treatments, scientists at Harvard Medical School have identified a new molecular brake that hinders the ability of T cells to attack tumors.

1 Sep 2025