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Scientists identify new genes associated with familial Meniere's disease

A team of scientists from the University of Granada (UGR) and GENYO (Pfizer-University of Granada-Andalusian Government Centre for Genomics and Oncological Research—led by Pablo Roman-Naranjo and Jose Antonio López-Escámez, researcher in charge of the Biohealth Research Institute in Granada (ibs.GRANADA)—has identified new genes associated with familial Meniere's disease.

1 Dec 2021

Researchers genetically map cell types that make up the mouse iris

Johns Hopkins Medicine researchers report they have genetically mapped the cell types that make up the mouse iris — the thin disc of pigmented tissue that, in humans, gives eyes their distinct colors.

30 Nov 2021

Breakthrough discovery paves the way for brain-like computers

Research has long strived to develop computers to work as energy efficiently as our brains. A study, led by researchers at the University of Gothenburg, has succeeded for the first time in combining a memory function with a calculation function in the same component.

30 Nov 2021

Clinical drug research for the treatment of CNS and neurological disorders

Frontiers in Clinical Drug Research - CNS and Neurological Disorders is a book series that brings updated reviews to readers interested in advances in the development of pharmaceutical agents for the treatment of central nervous system (CNS) and other nerve disorders.

29 Nov 2021

Persistent opioid use among 12% of patients after cardiac implantable electronic device procedures

About 12 percent of patients who receive implantable cardiac devices such as a pacemaker or defibrillator and fill an opioid prescription after surgery will consistently use the pain medication in the months afterward, raising the potential for addiction following these common procedures and identifying another pathway that could contribute to the national opioid crisis, according to a new study by researchers at the Perelman School of Medicine at the University of Pennsylvania.

26 Nov 2021

Minimally invasive ablation procedure offers long-term relief after knee replacement surgery

A minimally invasive ablation procedure offers long-term relief for patients who experience chronic and debilitating pain after knee replacement surgery, according to a study being presented next week at the annual meeting of the Radiological Society of North America.

24 Nov 2021

Adolescent and young adult ASD patients show changes in the brain's white matter microstructure

Researchers at Yale University analyzing specialized MRI exams found significant changes in the microstructure of the brain's white matter in adolescents and young adults with autism spectrum disorder (ASD) compared to a control group, according to research being presented next week at the annual meeting of the Radiological Society of North America.

23 Nov 2021

Study confirms safety of electroconvulsive therapy for treatment of mental conditions

The safety concerns associated with electroconvulsive therapy (ECT) are unwarranted, according to a new study in Frontiers in Psychology.

23 Nov 2021

Semiflexible optoelectrodes for high-resolution neuron readout and stimulation with low damage

The use of electrodes placed inside the brains of laboratory specimens has pushed the field of neuroscience to new findings for decades.

23 Nov 2021

GABA secreted by B-cells blunts the body's cytotoxic T-cell-based response to tumors

A group of scientists led by researchers from the RIKEN Center for Integrative Medical Sciences have discovered that B-cells, a type of immune cell, secrete the neurotransmitter GABA, and also found that the GABA secreted by the B-cells promoted the emergence of anti-inflammatory macrophages, blunting the body's cytotoxic T-cell-based response to tumors.

21 Nov 2021

Repurposed ALS drug could slow gradual brain cell loss in Niemann-Pick disease type C1

Riluzole, a drug approved to treat amyotrophic lateral sclerosis (ALS), a disease affecting nerve cells controlling movement, could slow the gradual loss of a particular brain cell that occurs in Niemann-Pick disease type C1 (NPC1), a rare genetic disorder affecting children and adolescents, suggests a study in mice by scientists at the National Institutes of Health.

20 Nov 2021

ALS also causes retinal alterations, study reveals

Amyotrophic lateral sclerosis (ALS), characterized by harm to brain neurons and to the spinal cord, also affects the tissue of the retina, according to a study headed up by Universidad Complutense de Madrid.

16 Nov 2021

Study identifies a host factor that reflects different levels of inflammation within mild COVID-19 cases

A new study investigates serum from COVID-19 convalescents and uninfected individuals to determine the molecular mechanisms of host responses.

15 Nov 2021

Study offers new insight into the role of tau proteins in ALS pathogenesis

A team led by investigators at Massachusetts General Hospital has shown that people living with amyotrophic lateral sclerosis (ALS), or Lou Gehrig's disease, who carry a mutation in the C9orf72 gene exhibit elevated levels of tau and phosphorylated tau protein in the motor cortex region of the brain.

15 Nov 2021

Can COVID-19 vaccination lead to neurological complications?

A new review article discusses the neurological side effects due to SARS-CoV-2 vaccination.

14 Nov 2021

Study: Patients meeting a particular criteria need invasive procedures to treat chronic neck pain

The use of radiofrequency ablation--targeted heat from an electrical current to ease nerve pain--may be helpful for treating chronic neck pain, but only in patients meeting particular criteria, conclude evidence-based consensus guidelines, published online in the journal Regional Anesthesia & Pain Medicine.

12 Nov 2021

Study links noise-induced inner ear nerve damage to endolymphatic hydrops

Exposure to loud noise, such as a firecracker or an ear-splitting concert, is the most common preventable cause of hearing loss. Research suggests that 12% or more of the world population is at risk for noise-induced loss of hearing.

11 Nov 2021

Special bioactive scaffolds lead to greater functional recovery from spinal cord injury in mice

In mice with a spinal cord injury, mixing materials including bioactive sequences formed a polymer meshwork that improved axon regrowth, angiogenesis, and neuronal cell survival.

11 Nov 2021

Exercise reduces upper limb disability after breast cancer surgery

Women who exercise shortly after having non-reconstructive breast cancer surgery appear to regain better shoulder and arm mobility and experience less pain than those who receive standard care, suggests a study published by The BMJ today.

11 Nov 2021

UArizona researchers get closer to developing a safe, effective non-opioid pain reliever

Researchers at the University of Arizona Health Sciences are closer to developing a safe and effective non-opioid pain reliever after a study showed that a new compound they created reduces the sensation of pain by regulating a biological channel linked to pain.

10 Nov 2021

Nerve News and Research

Scientists identify new genes associated with familial Meniere's disease

Researchers genetically map cell types that make up the mouse iris

Breakthrough discovery paves the way for brain-like computers

Clinical drug research for the treatment of CNS and neurological disorders

Persistent opioid use among 12% of patients after cardiac implantable electronic device procedures

Minimally invasive ablation procedure offers long-term relief after knee replacement surgery

Adolescent and young adult ASD patients show changes in the brain's white matter microstructure

Study confirms safety of electroconvulsive therapy for treatment of mental conditions

Semiflexible optoelectrodes for high-resolution neuron readout and stimulation with low damage

GABA secreted by B-cells blunts the body's cytotoxic T-cell-based response to tumors

Repurposed ALS drug could slow gradual brain cell loss in Niemann-Pick disease type C1

ALS also causes retinal alterations, study reveals

Study identifies a host factor that reflects different levels of inflammation within mild COVID-19 cases

Study offers new insight into the role of tau proteins in ALS pathogenesis

Can COVID-19 vaccination lead to neurological complications?

Study: Patients meeting a particular criteria need invasive procedures to treat chronic neck pain

Study links noise-induced inner ear nerve damage to endolymphatic hydrops

Special bioactive scaffolds lead to greater functional recovery from spinal cord injury in mice

Exercise reduces upper limb disability after breast cancer surgery

UArizona researchers get closer to developing a safe, effective non-opioid pain reliever

How Omics Technologies Are Transforming Biological Research and Drug Discovery

How microplastics and bacteria interact to drive antibiotic resistance

Single-cell proteomics: Revealing proteome diversity from cellular heterogeneity to non-canonical biology

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