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Modifying Oncolytic Adenoviruses to Target Pancreatic Cancer

Pancreatic cancer is one of the less common but deadliest cancers. Modified oncolytic adenoviruses represent an alternative to chemotherapy and targeted therapies, which have a high mortality rate.

9 Mar 2018

New study examines origin of cryptococcosis within the central nervous system

A particular fungal infection is responsible for more than 220,000 cases of cryptococcosis worldwide each year in people with HIV and AIDS, with nearly 181,000 of those resulting in death.

8 Mar 2018

Scientists discover 36 previously unknown genes implicated in heart failure

One in four deaths in the United States each year are due to heart disease, according to the Centers for Disease Control and Prevention. It's the leading killer of both men and women, but the disease's genetic complexity makes it difficult to treat.

8 Mar 2018

Health care revamped at L.A. county jails

Michael Callahan, an outgoing 43-year-old carpenter, landed in a Los Angeles County jail last September because of what he said were "bad decisions and selling drugs."

8 Mar 2018

Researchers identify new mechanism to disrupt HIV latency

HIV, the virus that causes AIDS, has a secret life. Though anti-retroviral therapy can reduce its numbers, the virus can hide and avoid both treatments and the body's immune response.

8 Mar 2018

Scientists link protein to seizure suppression

According to a new study, seizures can be suppressed in the brain by a protein called T-cell intracellular antigen-1 (TIA-1).

8 Mar 2018

Of ‘miracles’ and money: Why hemophilia drugs are so expensive

When Landon Morris was diagnosed with hemophilia shortly after birth, his mother, Jessica Morris, was devastated. "It was like having your dreams — all the dreams you imagined for your child — just kind of disappear," she recalled.

8 Mar 2018

Scientists discover connection between breast cancer protein and pediatric cancer

Scientists with the Greehey Children's Cancer Research Institute at UT Health San Antonio have discovered a surprising connection between a breast cancer protein, BRCA1, and a pediatric cancer called Ewing sarcoma.

8 Mar 2018

Research shows link between fluoroquinolone antibiotics and increased risk of aortic disease

New research from a Swedish and Danish team of researchers led from Karolinska Institutet lend additional support to a link between treatment with fluoroquinolone antibiotics and an increased risk of acute aortic disease. The study is published in the esteemed journal The BMJ.

8 Mar 2018

Study investigates use of drugs for the stomach and risk of major depressive disorder

A new study investigating the relationship between one of the commonest type of drugs used for protecting the stomach is presented in the current issue of Psychotherapy and Psychosomatics.

8 Mar 2018

Study identifies genetic defect linked to heart failure in African Americans

Heart failure is more common, develops earlier and results in higher rates of illness and death in African Americans than in whites.

7 Mar 2018

Slow-release injectable gel boosts toxicity of cancer-fighting immunotherapy drugs

An immunotherapy drug embedded in a slow-release hydrogel invented at Rice University in collaboration with the University of Texas Health Science Center at Houston appears to be highly effective at killing cancer cells.

7 Mar 2018

Researchers determine cause of difficult-to-control mitochondrial diseases

A Japanese research group has discovered that taurine is conjugated with mitochondrial transfer RNAs (tRNAs), small RNAs that decode genetic information, and that taurine deficiency in tRNA dramatically reduces both mitochondrial protein translation and impairs mitochondrial membrane integrity.

7 Mar 2018

Prevention and treatment of drug-induced hearing loss

A new special publication orchestrated by five of the nation's leading hearing experts compiles the latest research into hearing loss caused by drugs and solvents - how it occurs, how to treat it, and how to prevent it.

7 Mar 2018

Study finds reduced risk of dislocations with dual mobility hip replacement

More than 330,000 total hip replacements are performed in the United States each year. Overall, it is a highly successful procedure. However, as with all surgeries, a risk for complications exists.

7 Mar 2018

Innovative program seeks to eliminate HCV in Iceland

A new Journal of Internal Medicine study describes an innovative program to eliminate hepatitis C virus (HCV) as a public health threat in Iceland.

7 Mar 2018

Early life stress or trauma could rewire the brain for later neuropathological disorders

Federal researchers have discovered that severe stress or trauma early in life could actually change how the brain responds to stress hormones, essentially "re-wiring" the brain for later neuropathological disorders, according to a study, "A role for corticotrophin releasing factor signaling in the lateral habenula and its modulation by early life stress," published in Science Signaling, March 6.

7 Mar 2018

New study indicates possible misuse or abuse of ADHD medication

A new British Journal of Clinical Pharmacology study indicates that methylphenidate, a central nervous system stimulant approved to treat attention deficit hyperactivity disorder (ADHD) and narcolepsy, may be subject to misuse and/or abuse.

7 Mar 2018

FDA expands approval of smaller size replacement heart valve for treating newborn pediatric patients

The U.S. Food and Drug Administration today expanded the approval of a heart valve to include a size small enough to be used in newborn pediatric patients to treat heart defects. Specifically, the agency approved the Masters Series Mechanical Heart Valve with Hemodynamic Plus Sewing Cuff to include the 15-mm valve size, making it the smallest mechanical heart valve approved in the world.

7 Mar 2018

FDA approves new tests to detect tickborne parasite in human plasma and whole blood samples

The U.S. Food and Drug Administration today approved the Imugen Babesia microti Arrayed Fluorescent Immunoassay, for the detection of antibodies to Babesia microti (B. microti) in human plasma samples, and the Imugen Babesia microti Nucleic Acid Test (NAT), for the detection of B. microti DNA in human whole blood samples.

7 Mar 2018