Hospital News and Research

RSS

Assessing the integrity of remdesivir clinical trial during COVID-19 pandemic

As acknowledged in the first remdesivir double-blind placebo-controlled clinical trial addressing treatment for COVID-19 recently published in Lancet (Wang, et al., April 29, 2020), a statistician at Rutgers Cancer Institute of New Jersey was called on to guard the integrity of that trial.

4 Jun 2020

SARS-CoV-2 gene deletions may cause milder infections and increase human-to-human transmission

In their recent paper released on the bioRxiv preprint server, a research group from Spain demonstrated how genome changes and deletions in severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) could represent a strategy of natural selection used for lessening the impact of infection in order to increase viral transmission potential.

4 Jun 2020

Alpaca-derived antiviral agent neutralizes SARS-CoV-2

Researchers at Karolinska University Hospital and the University of Cape Town have identified an antibody fragment that targets the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) spike protein and potently neutralizes the virus.

4 Jun 2020

Universal preoperative screening of pediatric patients for COVID-19 improves safety

Universally screening pediatric patients for COVID-19 before they undergo surgical procedures has allowed hospitals to improve safety by identifying all patients who test positive for the virus, half of whom have no symptoms, according to new research led by Children's Hospital of Philadelphia

4 Jun 2020

New insights into how parenteral oil emulsions prevent liver disease in preterm babies

Infants born prematurely may require parenteral or intravenous nutrition to provide the necessary nourishment, as their digestive system is immature and cannot digest nutrients.

4 Jun 2020

3D facial imaging could speed diagnoses of genetic syndromes

Most children with rare genetic diseases spend years undergoing medical tests and waiting for a diagnosis -- a long, exhausting process that takes its toll on children and their families. Almost half of these children never get a definitive diagnosis.

4 Jun 2020

Natural molecules that stimulate dopamine production may help reverse Parkinson's disease

Investigators have identified two molecules naturally produced by the body that stimulate the production of dopamine, the molecule that is in short supply in the brains of patients with Parkinson's disease.

4 Jun 2020

Intranasal delivery of MSC-EVs shows promise for treating Alzheimer's disease

In the search for a cure for Alzheimer's disease, mesenchymal stem cells and their derived extracellular vesicles (MSC-EVs) offer much promise, thanks to their protective and anti-inflammatory properties.

4 Jun 2020

Study reveals biochemical alterations in patients with Lesch-Nyhan disease

An international study by the Institute of Neuroscience of the UAB, Emory University and Hospital Universitario La Paz, published in the PNAS journal, shows that patients suffering from Lesch-Nyhan, a rare neurological disease, present biochemical alterations in skin cells (fibroblasts), urine and cerebrospinal fluid.

4 Jun 2020

Hairy human skin grown from pluripotent stem cells

Building on years of groundbreaking discoveries in stem cell research, scientists from Indiana University School of Medicine and Harvard Medical School have determined how to grow hairy skin using human stem cells--developing one of the most complex skin models in the world.

4 Jun 2020

Hydroxychloroquine not able to prevent development of COVID-19, UMN trial shows

Today, University of Minnesota Medical School researchers published the results from the first randomized clinical trial testing hydroxychloroquine for the post-exposure prevention of COVID-19.

4 Jun 2020

Cases of alcohol-related liver disease will rise dramatically in coming years, shows study

Alcohol-related liver disease is currently the most common reason for liver transplantation in the United States. In recent years, high-risk drinking of alcohol--defined as exceeding daily drinking limits (more than 4 or 5 standard drinks for women and men, respectively) at least weekly for a whole year--has increased in nearly all sociodemographic groups, especially in women.

4 Jun 2020

COVID-19 can increase stroke risk in young healthy people

Young patients with no risk factors for stroke may have an increased risk if they have contracted COVID-19, whether or not they are showing symptoms of the disease.

4 Jun 2020

New platform can speed up the development of novel antibiotics

Harmful bacteria react less and less to common antibiotics. The infections they cause are therefore increasingly deadly.

4 Jun 2020

In hard-hit areas, COVID’s ripple effects strain mental health care systems

In late March, Marcell's girlfriend took him to the emergency room at Henry Ford Wyandotte Hospital, about 11 miles south of Detroit.

4 Jun 2020

COVID-19 pandemic may cause long-term effects and increase healthcare costs, says GlobalData

As many COVID-19 patients may experience long-term complications from the illness such as intensive care unit delirium, post-traumatic stress disorder, lung damage, heart damage and possible neurological issues, GlobalData expects the market for these treatments to increase due to the COVID-19 pandemic as recovered patients may need long-term care for these issues after being released from the intensive care unit and the hospital.

4 Jun 2020

Exploring data transparency and quality measurements in Austrian healthcare system

A crisis like the corona pandemic demonstrates how important reliable information and transparent communication are, particularly when dealing with such a sensitive area as health.

4 Jun 2020

Protein markers could help predict how ill a COVID-19 patient will become

Researchers at the Francis Crick Institute and Charité – Universitätsmedizin Berlin have identified 27 protein biomarkers that could be used to predict whether a patient with COVID-19 is likely to become severely ill with the disease.

4 Jun 2020

Study reveals opportunity to improve outcomes in young children with concussion

Head injuries that lead to concussions can happen at any age, and children impacted by concussions have different needs and recovery patterns.

4 Jun 2020

27 protein biomarkers predict COVID-19 severity in patients

Some patients infected with the novel coronavirus may experience only mild symptoms, while others may need medical care due to severe illness. People who are at a high risk of developing severe coronavirus disease (COVID-19) include older adults and those with underlying health conditions. However, severe disease has also been seen in young people with no underlying disease.

4 Jun 2020