Drugs News and Research

RSS

InSysBio evaluates tau protein phosphorylation related targets for treatment of AD

InSysBio continues to investigate the mechanisms underlying Alzheimer's disease using the quantitative systems pharmacology modeling approach. The part of QSP model describing tau protein was published in the PLOS ONE journal. This is one of more than dozen InSysBio publications in AD area during last seven years.

28 Feb 2018

Failed osteoarthritis drug may help lessen opioid dependence

A new study from Indiana University suggests that a drug proven safe for use in people may prevent opioid tolerance and physical dependence when used in combination with opioid-based pain medications.

27 Feb 2018

Researchers successfully graft human neural stem cells into monkeys with spinal cord injuries

Led by researchers at University of California San Diego School of Medicine, a diverse team of neuroscientists and surgeons successfully grafted human neural progenitor cells into rhesus monkeys with spinal cord injuries.

27 Feb 2018

Telomere length testing can alter treatment decisions for certain diseases

Research led by Johns Hopkins physicians and scientists shows that a test for measuring the length of DNA endcaps, called telomeres, which has a variability rate of 5 percent, can alter treatment decisions for patients with certain types of bone marrow failure.

27 Feb 2018

Fresh insights into depression could pave way for new therapies

Fresh insights into changes in the brain linked to depression could pave the way for new therapies.

27 Feb 2018

UC receives $1.75 million grant for epilepsy research

Research scientist Jianxiong Jiang, PhD, doesn't just want to treat acquired epilepsy...he hopes to prevent it.

27 Feb 2018

ASU researchers uncover crucial step in telomerase enzyme catalytic cycle

Can we stay young forever, or even recapture lost youth? Research from the laboratory of Professor Julian Chen in the School of Molecular Sciences at Arizona State University recently uncovered a crucial step in the telomerase enzyme catalytic cycle.

27 Feb 2018

Artificial intelligence methods used for developing precision cancer medicine

A patient's own molecular data can be used to identify, with the use of artificial intelligence methods, the best combinatorial multi-drug therapy for that patient. Network modelling plays a major role in this line of work.

27 Feb 2018

Researchers develop new tool that provides 3D view of metabolic processes

An international team of researchers has developed a computational resource that provides a 3D view of genes, proteins and metabolites involved in human metabolism.

27 Feb 2018

ANU research explores way to reduce unwanted side-effects of common drugs

New research from The Australian National University has drilled down to the molecular level to find similarities across six pharmaceutical drugs used in pain relief, dentist anesthetic, and treatment of epilepsy, in a bid to find a way to reduce unwanted side-effects.

27 Feb 2018

Study suggests novel approach for protecting diabetes patients from vascular disease

Recent findings suggest a novel approach for protecting people with diabetes from their higher risk of advanced blood vessel disease, which sets the stage for early heart attacks and strokes.

27 Feb 2018

Repurposing leukemia drugs may be effective approach for treating metastatic melanoma patients

Data from a new study led by University of Kentucky Markey Cancer Center researchers shows that repurposing drugs used to treat leukemia has promise for preventing melanoma metastasis.

26 Feb 2018

University of Illinois at Chicago awarded $4.6 million NIH grant for chronic pain research

The University of Illinois at Chicago has been awarded a $4.6 million grant from the National Heart, Lung, and Blood Institute to study the molecular neurobiology of chronic pain in patients with sickle cell disease and to develop potential new drug treatments.

26 Feb 2018

New discovery may allow doctors to treat inflammation in neurodegenerative diseases

A new discovery about the immune system may allow doctors to treat harmful inflammation that damages the brain in neurodegenerative diseases such as Alzheimer's. It might also let doctors save patients from the potentially deadly inflammation of sepsis, a full-body infection that kills a quarter-million Americans every year.

26 Feb 2018

New discovery could help understand and treat glaucoma

Researchers have discovered two distinct groups of short molecules that regulate gene expression in the eyes of people with two different forms of glaucoma.

26 Feb 2018

Research provides new directions in understanding and fighting glaucoma

Two distinctive handfuls of short molecules that regulate gene expression have been found in the eye fluid of patients with two distinct types of vision degenerating glaucoma.

26 Feb 2018

Researchers develop first analytical method to evaluate new cyanide and mustard gas antidote

To develop antidotes for chemical agents, such as cyanide and mustard gas, scientists need analytical methods that track not only the level of exposure but also how the drug counteracts the effects of the chemical.

24 Feb 2018

Well-being of individuals matters after AOD treatment

Alcohol and other drug (AOD) treatment and recovery research typically focuses on outcomes such as 'days abstinent.' Yet the degree to which individuals may be functioning better physically, socially and psychologically, how happy they may be, and their levels of self-esteem may be equally important as measures of progress.

24 Feb 2018

Connection between heart disease and cancer treatment

Advances in cancer treatment have resulted in a growing number of cancer survivors. However, powerful treatments such as chemotherapy, radiation treatments and some cancer drugs are not without their risks, including the potential for serious, long-term damage to the heart.

24 Feb 2018

Discovery may result in new medication to build stronger muscles in old age

As we grow older, our muscular function declines. A new study by researchers at Karolinska Institutet in Sweden shows how an unexpectedly high number of mutations in the stem cells of muscles impair cell regeneration.

23 Feb 2018