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Study identifies novel mechanism by which tumors can resist cancer immunotherapy

A Ludwig Cancer Research study led by Benoit Van den Eynde, Director of Ludwig Brussels, has identified a novel mechanism by which tumors of the aggressive skin cancer melanoma can resist cancer immunotherapy.

10 Nov 2017

New gene therapy for blindness may soon be reality

Patients who had lost their sight to an inherited retinal disease could see well enough to navigate a maze after being treated with a new gene therapy, according to research presented today at AAO 2017, the 121st Annual Meeting of the American Academy of Ophthalmology.

10 Nov 2017

Study identifies promising treatment to reduce brain injury in babies

Research-clinicians at Children's National Health System led the first study to identify a promising treatment to reduce or prevent brain injury in newborns who have suffered hypoxia-ischemia, a serious complication in which restricted blood flow deprives the brain of oxygen.

10 Nov 2017

Russian scientists uncover previously unknown effect of leukemia drug

Researchers from RUDN University and Institute of Biomedical Chemistry of the Russian Academy of Sciences have identified an alternative mechanism for the effective antitumor drug -- an enzyme called L-asparaginase.

10 Nov 2017

OSA may put elderly people at increased risk of developing Alzheimer's disease

Obstructive sleep apnea (OSA) may put elderly people at greater risk of developing Alzheimer's disease (AD), according to new research published online in the American Thoracic Society's American Journal of Respiratory and Critical Care Medicine.

10 Nov 2017

Researchers develop new method that can curb spread of superbugs

Researchers from ITMO University and Center of Physical and Chemical Medicine developed an algorithm capable of tracking the spread of antibiotic resistance genes in gut microbiota DNA and revealed additional evidence of resistance genes transfer between different bacterial species.

10 Nov 2017

Malaria parasites’ decision making influenced by fatty molecule in human blood

Depletion of a fatty molecule in human blood propels malaria parasites to stop replicating and causing illness in people and instead to jump ship to mosquitoes to continue the transmission cycle, according to a new study by an international research team.

9 Nov 2017

UB researcher explores link between signals in the brain's reward system and overeating, drug addiction

Why are some people able to stop after eating just a few potato chips, while others aren't satisfied until the bag is nothing but crumbs? The answer may lie in the signals acting in the brain's reward system.

9 Nov 2017

KU Leuven researchers unravel how cell division timer works

Human cells use a timer to divide: each cell gets at least 30 minutes to divide its genetic material between the nuclei of two daughter cells.

9 Nov 2017

CBT offers valuable treatment alternative for millions taking opioids for chronic pain

By teaching patients better strategies for coping with chronic pain, cognitive behavioral therapy is a valuable treatment alternative for the millions of Americans taking opioids for noncancer pain, according to an article in the Journal of Psychiatric Practice. The journal is published by Wolters Kluwer.

9 Nov 2017

Elevated levels of chronic stress hormones may promote EGFR inhibitor resistance in NSCLC patients

Elevated levels of chronic stress hormones, such as those produced by psychological distress, may promote resistance to drugs commonly used to treat lung cancer patients with EGFR mutations, according to new research from The University of Texas MD Anderson Cancer Center.

9 Nov 2017

3D cultured spheroids could drive precision treatment for ovarian cancer

Honeycomb-like arrays of tiny, lab-grown cancers could one day help doctors zero in on individualized treatments for ovarian cancer, an unpredictable disease that kills more than 14,000 women each year in the United States alone.

9 Nov 2017

Researchers find way to improve immunotherapy drugs’ impact while limiting side effects

By connecting highly effective cancer immunotherapy drugs such as anti-CTLA4 (ipilimumab) and anti-PD-L1 (atezolizumab) to peptides that bind to tissues in and around tumors, a research team based at the University of Chicago found a way to improve the drugs' impact while limiting treatment-related side effects.

9 Nov 2017

Women with ER-positive breast cancer face disease recurrence risk years after treatment ends

Even 20 years after a diagnosis, women with a type of breast cancer fueled by estrogen still face a substantial risk of cancer returning or spreading, according to a new analysis from an international team of investigators published in the New England Journal of Medicine.

9 Nov 2017

Complete new skin from transgenic stem cells for boy with rare genetic disease

Hassan, a then seven-year-old boy from Germany, in 2015, presented to the doctors with a rare skin disease called junctional epidermolysis bullosa or JEB. This condition leaves the skin thin and papery and easily breakable. It has been compared to “butterfly wings” because of their fragile nature.

8 Nov 2017

Orthocell earns CE Mark approval for CelGro collagen medical device

Regenerative medicine company Orthocell Limited is pleased to announce receipt of European regulatory approval (CE Mark) for its CelGro collagen medical device.

8 Nov 2017

New gene therapy trial for X-linked myotubular myopathy offers hope to children

Ann & Robert H. Lurie Children's Hospital of Chicago is one of the few centers participating in ASPIRO, an international Phase 1/2 clinical trial of a gene therapy product called AT132 for X-linked myotubular myopathy – a rare disease characterized by severe muscle weakness, breathing difficulty and early death.

8 Nov 2017

Therapy News and Research

Study identifies novel mechanism by which tumors can resist cancer immunotherapy

New gene therapy for blindness may soon be reality

Study identifies promising treatment to reduce brain injury in babies

Russian scientists uncover previously unknown effect of leukemia drug

OSA may put elderly people at increased risk of developing Alzheimer's disease

Researchers develop new method that can curb spread of superbugs

Malaria parasites’ decision making influenced by fatty molecule in human blood

UB researcher explores link between signals in the brain's reward system and overeating, drug addiction

KU Leuven researchers unravel how cell division timer works

CBT offers valuable treatment alternative for millions taking opioids for chronic pain

Elevated levels of chronic stress hormones may promote EGFR inhibitor resistance in NSCLC patients

3D cultured spheroids could drive precision treatment for ovarian cancer

Researchers find way to improve immunotherapy drugs’ impact while limiting side effects

Women with ER-positive breast cancer face disease recurrence risk years after treatment ends

Complete new skin from transgenic stem cells for boy with rare genetic disease

Orthocell earns CE Mark approval for CelGro collagen medical device

New gene therapy trial for X-linked myotubular myopathy offers hope to children

Leg ulcers may heal faster with exercise, study suggests

Research: Prognosis for people with diabetic foot ulcers worse than previously thought

Discontinuation of hormone therapy linked to increased risk of cardiac, stroke death

Industry Focus eBook - Neurology/Neuroscience - 2nd edition eBook

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

Advancing Intracellular Delivery with LumiPore®

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