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NUS scientists breathe new life into an existing drug to fight T-cell acute lymphoblastic leukemia

A team of researchers from the Cancer Science Institute of Singapore at the National University of Singapore, led by Associate Professor Takaomi Sanda and Dr Lim Fang Qi, has breathed new life into an existing drug—combatting a type of blood cancer called T-cell acute lymphoblastic leukemia, or T-ALL.

30 Jan 2023

Patients with myelofibrosis show improvement in disease-related symptoms when treated with momelotinib

Patients with myelofibrosis had clinically significant improvement in disease-related symptoms, including anemia and spleen enlargement, when treated with the targeted therapy momelotinib, according to results from the international Phase III MOMENTUM trial led by researchers at The University of Texas MD Anderson Cancer Center.

29 Jan 2023

Treatment to boost white blood cells may benefit patients with glioblastoma

A new study led by Washington University School of Medicine in St. Louis reveals at least one cause of low white blood cell counts in patients treated for glioblastoma and demonstrates a potential treatment strategy that improves survival in mice.

27 Jan 2023

Chemotherapy in the afternoon proved to be effective for female lymphoma patients

Chemotherapy is a commonly used regimen for cancer treatment, but it is also a double-edged sword. While the drugs are highly effective at killing cancer cells, they are also notorious for killing healthy cells in the body.

27 Jan 2023

Researchers solve an 80-year-old medical mystery that causes kidney damage in children

Researchers at the University of East Anglia have solved an 80-year-old medical mystery that causes kidney damage in children and can be fatal in babies

26 Jan 2023

Scientists illuminate how blood cancer treatments can lead to therapy-related myeloid neoplasms

Scientists at Sylvester Comprehensive Cancer Center at the University of Miami Miller School of Medicine have illuminated how treatments for multiple myeloma and other aggressive blood cancers can lead to future malignancies, called therapy-related myeloid neoplasms (tMNs).

25 Jan 2023

Chemotherapy schedule affects treatment outcomes in female DLBCL patients

24 Jan 2023

Study provides an estimate of people in the United States with VEXAS syndrome

About 13,200 men and another 2,300 women in the United States over age 50 are estimated to have VEXAS syndrome, according to a new study led by researchers at NYU Grossman School of Medicine.

24 Jan 2023

$Clear-cut treatment routine could reduce surgically treated ankle fractures$

Clear-cut treatment routine could reduce surgically treated ankle fractures

It has been shown that the percentage of ankle fractures that undergo surgery could be substantially reduced, from more than 30 per cent to 10 in the most common type of fracture.

24 Jan 2023

Research reveals the cellular origin of cancer-associated fibroblasts

A type of cell that plays a key role in pancreatic cancer can trace its origin back to a structure that forms during embryonic development, new research at MUSC Hollings Cancer Center shows.

20 Jan 2023

Metastatic Melanoma: key protein identified that aids the spread of skin cancer

In this interview, News-Medical spoke to Dr. Jeremy Carlton and Professor Victoria Sanz-Moreno about their latest research into the spread of skin cancer.

20 Jan 2023

Study generates a comprehensive genetic map to identify important genes that cause sarcoma

Several genes that cause sarcoma have been identified in the first comprehensive genetic map of sarcomas, generated by research led by Omico, the Garvan Institute of Medical Research and UNSW Sydney.

19 Jan 2023

Experimental regenerative medicine shows potential to restore bone in an animal

Bone loss is a part of aging that compromises quality of life and movement in many older people, but regenerative treatments to improve their health and well-being have been limited.

19 Jan 2023

How does the brain change with age?

Researchers discussed cellular hallmarks of brain aging and therapeutic interventions to rejuvenate cognitive brain functions.

19 Jan 2023

Study elucidates the potential role of STRO-001 in B-cell non-Hodgkin lymphoma

A new research paper was published in Oncotarget's Volume 14 on January 12, 2023, entitled, "Targeting CD74 in B-cell non-Hodgkin lymphoma with the antibody-drug conjugate STRO-001."

18 Jan 2023

Cedars-Sinai's Stem Cell and Bone Marrow Transplant Program recognized with two major hallmarks of quality

The Stem Cell and Bone Marrow Transplant Program at Cedars-Sinai Cancer was recently recognized with two important hallmarks of quality: official accreditation for CAR T-cell therapy, and a third year in a row ranking among the top adult bone marrow transplant programs in the U.S.

18 Jan 2023

Probiotic diminishes S. aureus bacterial colonization, Phase 2 trial shows

A promising approach to control Staphylococcus aureus bacterial colonization in people - using a probiotic instead of antibiotics - was safe and highly effective in a Phase 2 clinical trial.

17 Jan 2023

Reconstructing MRI scans with AI promises to expand MRI access to more patients

Artificial intelligence (AI) can reconstruct coarsely-sampled, rapid magnetic resonance imaging (MRI) scans into high-quality images with similar diagnostic value as those generated through traditional MRI, according to a new study by the NYU Grossman School of Medicine and Meta AI Research.

17 Jan 2023

Researchers develop innovative STAb therapy for a type of leukemia

Researchers of the Hospital Universitario 12 de Octubre in Madrid and the Josep Carreras Leukaemia Research Institute have developed a cell therapy for a type of leukemia which currently has very few treatment options.

16 Jan 2023

Study uncovers a new role for Slit2 signaling in stimulating Ewing sarcoma growth

A new research paper was published in Genes & Cancer on December 14, 2022, entitled, "Slit2 signaling stimulates Ewing sarcoma growth."

13 Jan 2023

Bone News and Research

NUS scientists breathe new life into an existing drug to fight T-cell acute lymphoblastic leukemia

Patients with myelofibrosis show improvement in disease-related symptoms when treated with momelotinib

Treatment to boost white blood cells may benefit patients with glioblastoma

Chemotherapy in the afternoon proved to be effective for female lymphoma patients

Researchers solve an 80-year-old medical mystery that causes kidney damage in children

Scientists illuminate how blood cancer treatments can lead to therapy-related myeloid neoplasms

Chemotherapy schedule affects treatment outcomes in female DLBCL patients

Study provides an estimate of people in the United States with VEXAS syndrome

Clear-cut treatment routine could reduce surgically treated ankle fractures

Research reveals the cellular origin of cancer-associated fibroblasts

Metastatic Melanoma: key protein identified that aids the spread of skin cancer

Study generates a comprehensive genetic map to identify important genes that cause sarcoma

Experimental regenerative medicine shows potential to restore bone in an animal

How does the brain change with age?

Study elucidates the potential role of STRO-001 in B-cell non-Hodgkin lymphoma

Cedars-Sinai's Stem Cell and Bone Marrow Transplant Program recognized with two major hallmarks of quality

Probiotic diminishes S. aureus bacterial colonization, Phase 2 trial shows

Reconstructing MRI scans with AI promises to expand MRI access to more patients

Researchers develop innovative STAb therapy for a type of leukemia

Study uncovers a new role for Slit2 signaling in stimulating Ewing sarcoma growth

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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