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Computer simulations yield promising vaccine candidate against SARS-CoV-2

In a recent study that appeared on a preprint server bioRxiv, scientists from India designed a multi-epitope peptide-based vaccine that predicted high immunogenic response in the population.

19 Apr 2020

Researchers discover unique structure and function of rotavirus VP3 protein

After eluding researchers for more than 30 years, the VP3 protein of rotavirus has finally revealed its unique structure and function to a team led by scientists at Baylor College of Medicine.

17 Apr 2020

Scientists predict how the novel coronavirus spreads in a typical household

A team of scientists recently carried out a study on the transmissibility of the virus in households. Simply put, they’re trying to predict how the virus spreads in a typical family: if one person gets sick, how many others get sick? How sick? How long would it take the family to recover? These are the practical questions this study tries to answer.

17 Apr 2020

Gimsilumab trial starts in first US patient with ARDS and COVID-19

The first American patient with COVID-19 and acute respiratory distress syndrome (ARDS) has been put on the drug gimsilumab at Temple University Hospital, as part of the BREATHE clinical trial. The trial, sponsored by Roivant Sciences, will evaluate the effectiveness of intravenous gimsilumab in preventing death in patients with COVID-19 and ARDS.

16 Apr 2020

Analyzing structure of the nipple to understand and fight breast cancer

Nipple-sparing mastectomy is gaining ground as a treatment or preventive measure for breast cancer, given the understandable desire among patients to preserve natural appearance as much as possible.

16 Apr 2020

Remdesivir drug stops novel coronavirus from replicating

Scientists from the University of Alberta have published findings that the antiviral drug remdesivir prevents replication of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) by inhibiting RNA replication. The study, published in April 2020 in the Journal of Biological Chemistry, follows on the heels of earlier reports from the same lab in February, showing the drug's effectiveness against the related Middle East Respiratory Syndrome (MERS) virus.

15 Apr 2020

Coronavirus able to survive near boiling point of water, study shows

A startling paper by a team of French scientists published in the preprint journal bioRxiv in April 2020 suggests that the novel coronavirus is capable of surviving at high temperatures. This could mean that laboratory technicians handling the virus are at danger of infection.

15 Apr 2020

New coronavirus possibly circulated within humans before COVID-19 pandemic

Genetic variation analysis and the evidence of recombination events point towards the conclusion that severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) might have circulated cryptically among humans for years, as reported by a recent paper on a preprint server bioRxiv.

15 Apr 2020

Novel coronavirus can be airborne for 13 feet

The novel coronavirus can travel up to 13 feet or 4 meters from patients in hospital wards, a new study has found. This is twice the distance current guidelines recommend for social distancing.

14 Apr 2020

The race is on for a coronavirus vaccine, 70 candidates, 3 at human trial stage

Amid the coronavirus disease (COVID-19) global pandemic that is infecting millions of people across the globe, hope sparks as the World Health Organization (WHO) reports that seventy vaccination trials for the novel coronavirus are underway, with three already at the human trial stage.

14 Apr 2020

Stray dogs possible origin of COVID-19 pandemic

After tracing coronavirus signatures in different species, a new research article published in the journal Molecular Biology and Evolution shows that stray dogs (more specifically dog intestines) may have acted as the origin of current severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic.

14 Apr 2020

Researchers develop synthetic scaffolds for tendon and ligament regeneration

Australia's love of sport means it has one of the highest rates of knee anterior cruciate ligament (ACL) injury and reconstruction in the world.

14 Apr 2020

Technologies converge on interacting surfaces in protein complexes

Researchers have fine-tuned a method to pinpoint surfaces within interacting large multi-protein complexes.

14 Apr 2020

New insights into the building blocks of periodontitis

Porphyromonas gingivalis is a major bacterial pathogen which leads to periodontitis also known as gum disease. In Japan, 80% of adults aged 35 and over suffer from this disease. What's more, P. gingivalis has also been linked to rheumatoid arthritis, cardiovascular disease, pancreatic cancer, and even Alzheimer's disease.

13 Apr 2020

How does COVID-19 attack the body?

The coronavirus disease (COVID-19) attacks the lungs, leading to pneumonia, and eventually, a cascade of serious complications. But how does COVID-19 kill? Is it the virus itself or the result of the person’s immune system response?

13 Apr 2020

Novel coronavirus attacks and destroys T cells, just like HIV

The immune system has many components that work together in protecting the body from foreign invaders. One of the most important types of immune cells is T lymphocytes or T cells, a type of white blood cell that acts as the core of adaptive immunity, the system that modifies the immune response to specific pathogens.

13 Apr 2020

Missing COVID-19 antibodies suggest mystery immune response

Researchers at Shanghai Public Health Clinical Center have made important discoveries about the immune response among patients who have recovered from mild COVID-19 disease that could help to inform prevention and treatment methods, as well as improve the efficacy of community testing.

13 Apr 2020

New technique for imaging proteins in 3D

A team of scientists including researchers at the National Synchrotron Light Source II (NSLS-II)--a U.S. Department of Energy Office of Science User Facility at DOE's Brookhaven National Laboratory--have demonstrated a new technique for imaging proteins in 3-D with nanoscale resolution.

13 Apr 2020

The building blocks of gum disease

A team of researchers has revealed the structure of adhesive pili and shed light on how they assemble, causing Periodontitis.

13 Apr 2020

Cats, ferrets more vulnerable to COVID-19 than dogs

A recent Chinese study published on the preprint server BioRxiv finds that cats and ferrets appear to be extremely vulnerable to the virus, but dogs, pigs, and poultry do not seem to contract it. As preprints, papers are not yet peer-reviewed, undergoing only basic scientific screening.

12 Apr 2020