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New 3D human brain tissue platform integrates all major brain cell types into a single culture

A new 3D human brain tissue platform developed by MIT researchers is the first to integrate all major brain cell types, including neurons, glial cells and the vasculature into a single culture.

17 Oct 2025

Research reveals how immune cells orchestrate the release of toxic granules

When immune cells strike, precision is everything. New research reveals how natural killer and T cells orchestrate the release of toxic granules – microscopic packages that destroy virus-infected or cancerous cells.

17 Oct 2025

Scientists discover why a powerful leukemia drug fails in most patients

Researchers from Rutgers Health and other institutions have discovered why a powerful leukemia drug eventually fails in most patients – and found a potential way to overcome that resistance.

17 Oct 2025

Runx1 overexpression triggers early intervertebral disc degeneration

A new research paper was published in Volume 17, Issue 9 of Aging-US on September 8, 2025, titled, "Runx1 overexpression induces early onset of intervertebral disc degeneration."

17 Oct 2025

New insights reveal persistent genome structure during cell division

Before cells can divide, they first need to replicate all of their chromosomes, so that each of the daughter cells can receive a full set of genetic material.

17 Oct 2025

AI predicts cell responses to drugs and genetic changes

Controlling the state of a cell in a desired direction is one of the central challenges in life sciences, including drug development, cancer treatment, and regenerative medicine.

16 Oct 2025

Cancer hijacks embryonic gene editors to fuel growth

Cancer cells are known to reawaken embryonic genes to grow. A new study reveals the disease also hijacks the proteins, or "editors", that control how those genes are read.

16 Oct 2025

Blocking key protein restores healthy lung function and reduces fibrosis in mice

Pulmonary fibrosis is a deadly disease in which the lungs become thickened and scarred, gradually losing their ability to deliver oxygen to the body.

16 Oct 2025

New personalized therapy boosts tamoxifen effectiveness in breast cancer patients

Breast cancer is the most common cancer among women worldwide (WHO, 2023). The Dr. Margarete Fischer-Bosch Institute of Clinical Pharmacology (IKP) has now developed a new therapy in a clinical study that tailors hormone treatment for breast cancer to the individual patient.

16 Oct 2025

Researchers discover new genetic cause of hereditary optic atrophy

A research team from the Medical University of Vienna and the Medical University of Graz has discovered a previously unknown genetic cause of hereditary optic atrophy, a degenerative disease of the optic nerve associated with gradual loss of vision.

16 Oct 2025

Advanced MRI technique reveals early markers of hereditary frontotemporal dementia

An international study led by researchers at Karolinska Institutet in Sweden demonstrates that it is possible to detect subtle changes in the brain and identify early signs of hereditary frontotemporal dementia using advanced brain imaging techniques.

16 Oct 2025

Uncovering a molecular weakness in Ewing sarcoma for targeted therapy

A research team at the Seville Biomedical Institute (IBis) has identified a new molecular mechanism that explains the high sensitivity of Ewing sarcoma (an aggressive bone cancer that mainly affects children and adolescents) to certain chemotherapy drugs, such as irinotecan.

16 Oct 2025

New breakthrough enables whole genome sequencing in hours

Boston Children's Hospital, along with Broad Clinical Labs and Roche Sequencing Solutions, has demonstrated that rapid genomic sequencing and interpretation are achievable in a matter of hours.

16 Oct 2025

Longevity gene offers hope for children with progeria

A new breakthrough in a rare genetic disease which causes children to age rapidly has been discovered using 'longevity genes' found in people who live exceptionally long lives - over 100 years old.

15 Oct 2025

CRISPR therapy shows promise against influenza in human lung chips

The Influenza A virus (IAV) has been the cause of six major flu pandemics, responsible for 50 to 100 million deaths globally.

15 Oct 2025

Experimental gene therapy restores immune system function in children with genetic immune disorder

An experimental gene therapy developed by researchers at UCLA, University College London and Great Ormond Street Hospital has restored and maintained immune system function in 59 of 62 children born with ADA-SCID, a rare and deadly genetic immune disorder.

15 Oct 2025

Air pollution and Parkinson’s: What a 292,000-person study reveals about hidden risks

Researchers in Northern Ireland examined whether exposure to fine particulate matter (PM2.5) and nitrogen dioxide (NO₂) increases the risk of Parkinson’s disease. While no overall link was found after adjusting for confounders, younger adults under 50 showed a modest association with PM2.5, raising questions about age-related susceptibility and diagnostic misclassification.

15 Oct 2025

Ancient lead exposure may have shaped human evolution and language

A groundbreaking international study changes the view that exposure to the toxic metal lead is largely a post-industrial phenomenon.

15 Oct 2025

ALS and MS share striking geographic patterns, research shows

A new study published in Nature's Scientific Reports indicates that amyotrophic lateral sclerosis (ALS) and multiple sclerosis (MS) have an extremely high geographic association, even after controlling for race, gender, wealth, latitude, and access to neurological healthcare.

15 Oct 2025

New triple action iron supplement restores iron levels without inflammation

Iron-deficiency anemia is a common condition marked by tiredness, headaches or ice cravings. But the oral iron supplements used to treat it can leave behind excess iron that causes inflammation and an upset stomach.

15 Oct 2025