Precision Medicine News and Research

RSS

Brain function changes could help diagnose and manage depression

Ever heard of the lateral habenula? Very few, outside of neuroscience, probably have. Yet a new study, published in the journal Neuron, shows that characteristic changes in the way this area of the brain fires can result in a total loss of will to do anything – which is characteristic of one form of depression.

29 Oct 2019

Genetic variations linked to declines in blood oxygen levels during sleep identified

Researchers have identified 57 genetic variations of a gene strongly associated with declines in blood oxygen levels during sleep. Low oxygen levels during sleep are a clinical indicator of the severity of sleep apnea, a disorder that increases the risk of heart disease, dementia, and death.

24 Oct 2019

Dartmouth scientist awarded grant to build new AI technologies for lung cancer management

Lung cancer is the second most common type of cancer and leading cause of cancer death in men and women, with non-small cell lung cancer (NSCLC) accounting for up to 90% of cases. Somatic mutations heavily impact the sensitivity of NSCLC patients to various drug treatments, and are critical for choosing the most effective targeted therapies for this cancer.

23 Oct 2019

Polymerized estrogen can protect nervous system cells and promote regeneration

Spinal cord damage that causes paralysis and reduced mobility doesn't always stop with the initial trauma, but there are few treatment options to halt increased deterioration -- and there is no cure.

23 Oct 2019

NCATS funds 'All of Us Research Program' to evaluate innovative DNA sequencing tools

The All of Us Research Program has selected the HudsonAlpha Institute for Biotechnology, Huntsville, Alabama, to evaluate the use of leading-edge DNA sequencing technologies that could someday improve diagnosis and treatment of many diseases, both common and rare.

18 Oct 2019

Development and assessment of NGS-based microsatellite instability assay

The assay has a clinically relevant five-day turnaround time and can be conducted on as little as 20 ng genomic DNA with a batch size of up to forty samples in a single run.

18 Oct 2019

Leading children's hospitals to use multi-year federal grant to scale up genomics research collaboration

With a shared vision of accelerating genomic discovery and improving patient outcomes, leaders from Boston Children's Hospital, Children's Hospital of Philadelphia, and Cincinnati Children's Hospital came together in 2015 to form the Genomics Research and Innovation Network.

17 Oct 2019

Regenstrief leaders share their expertise in artificial intelligence at workshop in South America

Two of Regenstrief Institute's leaders are sharing their expertise in artificial intelligence and data infrastructure at a workshop hosted by Brazil's National Institute of Science and Technology in Scientific Assisted Medicine in Sao Paulo, Brazil.

17 Oct 2019

Study represents a major step in seeking alternative cancer treatments for non-responders

Research led by VHIO's Alena Gros signposts a new, less invasive approach to identify killer T lymphocytes in patients with gastrointestinal tumors with low mutational burden who are refractory to approved immune-based treatments.

16 Oct 2019

Oxford Genetics and Sphere Fluidics announce a multi-partner collaboration

Oxford Genetics and Sphere Fluidics announce a multi-partner collaboration to expedite the development of automated microfluidic systems.

From Fluidic Sciences and Sphere Bio 16 Oct 2019

How dementia spreads: new study says it’s through neural networks

Scientists have found out a way to forecast the spread of brain atrophy, using prior research that shows how brain networks connect with each other to form a continuously linked pathway.

14 Oct 2019

Dementia spreads via synaptic connections between brain networks

In a new study, UC San Francisco scientists used maps of brain connections to predict how brain atrophy would spread in individual patients with frontotemporal dementia, adding to growing evidence that the loss of brain cells associated with dementia spreads via the synaptic connections between established brain networks.

14 Oct 2019

Advancements in the use of AI in Oncology explored at Cleveland

Artificial Intelligence, machine learning and smart computing are all rapidly transforming the global health and medical landscape, including at Case Western Reserve University and among its health-care partners in Northeast Ohio and beyond.

14 Oct 2019

$RESILIENT study tests benefit of ETA guided treatments for patients with advanced refractory cancers$

RESILIENT study tests benefit of ETA guided treatments for patients with advanced refractory cancers

RESILIENT was a single arm, open label, phase II/III study to test if label agnostic therapy regimens guided by Encyclopedic Tumor Analysis can offer meaningful clinical benefit for patients with relapsed refractory metastatic malignancies.

11 Oct 2019

Researchers develop customized drug treatment to bypass patient’s unique mutation

An unprecedented case at Boston Children's Hospital shows that it's possible to do something that's never been done before: identify a patient's unique mutation, design a customized drug to bypass it, manufacture and test the drug, and obtain permission from the Food and Drug Administration (FDA) to begin treating the patient -- all in less than one year.

11 Oct 2019

Pepscan announces increased GMP production capacity to facilitate clients' growth

Today, Pepscan announced that its GMP production capacity has doubled. Pepscan is an all-in-one partner in peptides, building on 25 years of experience in advancing and applying peptide expertise to facilitate clients in the development and production of peptides.

9 Oct 2019

New drug Aliskiren shows promise for heart failure patients

A study published in the International Journal of Molecular Sciences, as part of a special issue “Heart Failure: From Molecular Basis to Therapy”, in August 2019, shows that aliskiren, a drug approved by the US Food and Drug Administration (FDA), can improve survival for over 5 years, on average, and enhance life quality in patients who have been correctly diagnosed with heart failure.

9 Oct 2019

Aliskiren drug can delay progression of congestive heart failure, lengthen survival rates

Researchers at the University of Arizona College of Medicine - Phoenix have shown for the first time in preclinical studies that Aliskiren, a drug that inhibits the enzyme that regulates blood pressure, can delay the progression of congestive heart failure and lengthen survival rates.

8 Oct 2019

Study identifies genetic marker which could personalize treatment for Crohn's disease

The largest study ever to look at why an expensive and commonly used group of drugs fails some patients with Crohn's disease has identified a genetic marker which could individualize drug treatment.

7 Oct 2019

Common genetic variant explains why immunotherapy often fails in Crohn's disease

The reason why a commonly used range of immunotherapy drugs is not effective in some patients with Crohn’s disease has so far not been identified, until now.

7 Oct 2019

Precision Medicine News and Research

Brain function changes could help diagnose and manage depression

Genetic variations linked to declines in blood oxygen levels during sleep identified

Dartmouth scientist awarded grant to build new AI technologies for lung cancer management

Polymerized estrogen can protect nervous system cells and promote regeneration

NCATS funds 'All of Us Research Program' to evaluate innovative DNA sequencing tools

Development and assessment of NGS-based microsatellite instability assay

Leading children's hospitals to use multi-year federal grant to scale up genomics research collaboration

Regenstrief leaders share their expertise in artificial intelligence at workshop in South America

Study represents a major step in seeking alternative cancer treatments for non-responders

Oxford Genetics and Sphere Fluidics announce a multi-partner collaboration

How dementia spreads: new study says it’s through neural networks

Dementia spreads via synaptic connections between brain networks

Advancements in the use of AI in Oncology explored at Cleveland

RESILIENT study tests benefit of ETA guided treatments for patients with advanced refractory cancers

Researchers develop customized drug treatment to bypass patient’s unique mutation

Pepscan announces increased GMP production capacity to facilitate clients' growth

New drug Aliskiren shows promise for heart failure patients

Aliskiren drug can delay progression of congestive heart failure, lengthen survival rates

Study identifies genetic marker which could personalize treatment for Crohn's disease

Common genetic variant explains why immunotherapy often fails in Crohn's disease

Editorial Focus eBook - Peptides and Oligonucleotides (2nd edition) eBook

How ELRIG Is Helping Mid-Career Scientists Navigate Leadership, Career Change and Redundancy

The role of UV-Vis in biopharma QC

Applications Engineer

Latest News