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MicroRNAs in maternal blood may predict development of preeclampsia

Small non-coding RNA molecules, called microRNAs (miRNAs), found and measured in the blood plasma of asymptomatic pregnant women may predict development of preeclampsia, a condition characterized by high blood pressure and abnormal kidney function that affects roughly 5 to 8 percent of all pregnancies.

20 May 2020

Loss of smell added to the UK's official list of Covid-19 symptoms

The UK has joined the US, Europe and the World Health Organisation by including loss of smell or taste as an officially recognized symptom of Covid-19 – thanks in part to an international research project involving Professor Carl Philpott at the University of East Anglia.

20 May 2020

Australian COVID-19 prevention trial begins for frontline and allied healthcare workers

COVID SHIELD is a major collaborative effort led by the Walter and Eliza Hall Institute of Medical Research in partnership with human data science company IQVIA.

19 May 2020

COVID-19 associated with high thrombotic risk

COVID-19 is associated with a high incidence of venous thromboembolism, blood clots in the venous circulation, according to a study conducted by researchers at Brighton and Sussex Medical School, UK.

19 May 2020

Researchers propose a safer approach to splitting ventilators

As more Covid-19 patients experience acute respiratory distress, there has been much debate over the idea of sharing ventilators, which involves splitting air tubes into multiple branches so that two or more patients can be connected to the same machine.

19 May 2020

Gene mutation linked to MEF2C haploinsufficiency syndrome

A collaboration between scientists at the Medical University of South Carolina and clinicians at the Greenwood Genetic Center has yielded new findings about how a particular gene might regulate brain development.

19 May 2020

MGH researchers identify potential molecular targets for ALD drug development

Alcohol-related liver disease (ALD) is a deadly condition affecting more than 150 million people worldwide with no treatment available besides transplant.

19 May 2020

Sleep apnea may increase the risk of severe COVID-19, say researchers

An analysis conducted by researchers at the University of Turku and Turku University Hospital in Finland has suggested that obstructive sleep apnea (OSA) may be a risk factor for severe coronavirus disease 2019 (COVID-2019).

19 May 2020

To stem COVID, this small Indiana city decided to test all public-facing employees

Behind a nondescript strip mall in Carmel, Indiana, a short line of cars gathers mid-afternoon next to a large tent. Medical professionals stand out front, dressed head to toe in blue medical coveralls. People in the cars — many of them first responders — drive up to be tested for COVID-19.

19 May 2020

Early life antibiotic exposure linked to increased risk of childhood obesity

Very young children exposed to antibiotics at an early age (from birth to 12 months) are associated with higher risks of childhood obesity and increased adiposity in early to mid-childhood.

19 May 2020

Modified clinical trial design to meet urgent community needs during COVID-19 pandemic

A new paper published online in the Annals of the American Thoracic Society describes a nimble, pragmatic and rigorous multicenter clinical trial design to meet urgent community needs in the face of the COVID-19 pandemic.

19 May 2020

Phase IIB clinical trial initiated for treating hepatitis B-associated liver cancer

The first patients have been dosed in a multi-regional Phase IIB randomized, placebo-controlled clinical trial for the treatment of hepatitis B-associated liver cancer.

19 May 2020

NEJM Group releases a series of five Covid-19 interactive cases

NEJM Group today released Covid-19 Rx: Treatment Simulations, a series of five Covid-19 interactive cases that range from a mild self-limited flu-like illness to life-threatening multi-organ failure.

19 May 2020

Fewer traffic collisions during shutdown means longer waits for organ donations

On Day Two of the San Francisco Bay Area's stay-at-home orders in March, Nohemi Jimenez got into her car in San Pablo, California, waved goodbye to her 3-year-old son and drove to her regular Wednesday dialysis appointment.

19 May 2020

Gene variants can increase risk of schizophrenia, shows study

Variants in a gene of the human immune system cause men and women to have different vulnerabilities to the autoimmune diseases lupus and Sjögren's syndrome, according to findings published in the journal Nature.

19 May 2020

Researchers are developing a diagnostic test that predicts the advanced stages of COVID-19 patients

A research team from the University of Valencia, led by Professor Juan Saus from the Department of Biochemistry and Molecular Biology, is developing a project to provide the healthcare system with a diagnostic test that anticipates the entry into advanced stages of patients with COVID-19 and a scalable oral treatment for the disease.

19 May 2020

Study: Personalized ovarian cancer risk prediction reduces worries among a majority of women

Offering personalised ovarian cancer risk prediction to women shows that 98 per cent of participants felt less worried after finding out their ovarian cancer risk status, according to a study led by Queen Mary University of London.

19 May 2020

Mount Sinai researchers are first to use AI model to analyze COVID-19 patients

Mount Sinai researchers are the first in the country to use artificial intelligence (AI) combined with imaging, and clinical data to analyze patients with coronavirus disease (COVID-19).

19 May 2020

Primary care-based intervention promotes parent-teen communication

A primary care-based intervention to promote parent-teen communication led to less distress and increased positive emotions among adolescents, as well as improved communication for many teens, according to a new study by researchers at the Center for Parent and Teen Communication at Children's Hospital of Philadelphia (CHOP).

19 May 2020

Common cytokine profile in ARDS, severe COVID-19 and sepsis

Many lives have been lost to the severe pneumonic disease COVID-19 caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), during the ongoing pandemic. The reason for the critical lung injury that results in a fatal outcome in a significant minority of patients has been supposed to be the dramatic oversecretion of pro-inflammatory cytokines and chemokines triggered by the virus.

19 May 2020