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Penn scientists identify new therapeutic target for treatment of melanoma

Researchers in the Perelman School of Medicine at the University of Pennsylvania have identified a new therapeutic target for the treatment of melanoma.

16 Jan 2018

Scientists find increased risk of HIV outbreaks in Ukraine due to war-related migration

Conflict in Ukraine has increased the risk of HIV outbreaks throughout the country as displaced HIV-infected people move from war-affected regions to areas with higher risk of transmission, according to analysis by scientists.

16 Jan 2018

Lamprey genes provide clues to repair spinal cord damage, finds study

Researchers have found that several genes within an ancient species of fish can be used to provide clues in the treatment of spinal cord damage. The study titled, “Highly Conserved Molecular Pathways, Including Wnt Signaling, Promote Functional Recovery from Spinal Cord Injury in Lampreys,” appeared in the latest issue of the journal Scientific Reports.

15 Jan 2018

FDA grants approval for first drug to treat inherited breast cancer

The U.S. Food and Drug Administration today expanded the approved use of Lynparza (olaparib tablets) to include the treatment of patients with certain types of breast cancer that have spread (metastasized) and whose tumors have a specific inherited (germline) genetic mutation, making it the first drug in its class (PARP inhibitor) approved to treat breast cancer, and it is the first time any drug has been approved to treat certain patients with metastatic breast cancer who have a "BRCA" gene mutation.

15 Jan 2018

Stem cell transplant can effectively treat patients with rare autoimmune disease, study shows

An unusual autoimmune disease that causes skin and lung damage can be treated effectively by stem cell transplant, a new study in the New England Journal of Medicine has found.

12 Jan 2018

Discovery suggests new approach for targeting most-wanted molecular culprits in cancer

A discovery by scientists at Dana-Farber Cancer Institute and University of Texas Southwestern Medical Center presents drug developers with an entirely new tack in targeting one of the most-wanted molecular culprits in cancer.

12 Jan 2018

Researchers use novel PET tracer to assess myelin damage in mouse models of MS

The loss or damage of myelin, a cellular sheath that surrounds and insulates nerves, is the hallmark of the immune-mediated neurological disorder multiple sclerosis.

12 Jan 2018

Early testing for influenza symptoms can limit severe, life-threatening disease

As flu season picks up steam across the country, it's important for people to be tested very early after symptoms that are compatible with influenza start, since there are effective treatments that can limit severe, life-threatening disease and curtail transmission to others.

12 Jan 2018

Exposure to estrogen-mimicking compounds may reverse effects of breast cancer treatment

Scientists from The Scripps Research Institute have discovered that two estrogen-mimicking compounds found in many foods appear to potently reverse the effects of palbociclib/letrozole, a popular drug combination for treating breast cancer.

12 Jan 2018

Genetic analysis can enhance outcomes of depression treatment

The failure of drugs such as SSRIs, used to treat depression, can be a result of genetic variations in patients.

12 Jan 2018

Study finds overall pattern of commonality between Huntington's and Parkinson's

A new study strongly suggests that the brains of people who have died of Huntington's disease (HD) and Parkinson's disease (PD) show a similar response to a lifetime of neurodegeneration, despite being two very distinct diseases.

12 Jan 2018

RAS dimers essential for causing cancer, study shows

Mutated RAS genes are some of the most common genetic drivers of cancer, especially in aggressive cancers like pancreatic and lung cancer, but no medicines that target RAS are available despite decades of effort.

12 Jan 2018

Sunlight exposure may help lose weight

Putting on extra kilos during winters has been blamed on holiday treats and less physical activity. Now a new study shows that less exposure to be the key to putting on the weight. A sunny vacation might help lose that extra weight say researchers at University of Alberta in Canada. The study appeared in the journal Scientific Reports.

11 Jan 2018

Novel antifungal shows promise to stave off drug-resistant superbugs

Microscopic yeast have been wreaking havoc in hospitals around the world- creeping into catheters, ventilator tubes, and IV lines- and causing deadly invasive infection.

11 Jan 2018

Mount Sinai study uncovers potential link between Crohn's and Parkinson's in Jewish population

Mount Sinai Researchers have just discovered that patients in the Ashkenazi Jewish population with Crohn's disease (a chronic inflammatory of the digestive system) are more likely to carry the LRRK2 gene mutation.

11 Jan 2018

UPM researchers successfully simulate real-time migraine prediction system

UPM researchers, in collaboration with UCM and Hospital Universitario de la Princesa, have successfully simulated a system that alert patients to an incoming migraine crisis in real time. According to the simulation results, the reliability of this system is over 75%.

11 Jan 2018