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HSF1A stimulates more protein chaperones and reduces protein misfolding

Scientists at Duke University Medical Center have found some compounds that improve a cell's ability to properly "fold" proteins and could lead to promising drugs for degenerative nerve diseases, including Huntington's disease, Alzheimer's disease and Parkinson's disease.

20 Jan 2010

Officials debate merits of medical marijuana as coping tool in pain fight

As access to medical marijuana becomes more widespread, officials are debating its use as a pain-coping treatment and are easing rules for the sick to use the drug, The Wall Street Journal reports. "The U.S. Department of Justice has said it will not generally prosecute ill people under doctors' care whose use of the drug complies with state rules. New Jersey will become the 14th state to allow therapeutic use of marijuana, and the number is likely to grow. Illinois and New York, among others, are considering new laws."

20 Jan 2010

Researchers show how gliomas can evade drugs aimed at blocking EGFR

Researchers at the Ludwig Institute for Cancer Research (LICR) at the University of California, San Diego School of Medicine and Moores UCSD Cancer Center have shown one way in which gliomas, a deadly type of brain tumor, can evade drugs aimed at blocking a key cell signaling protein, epidermal growth factor receptor (EGFR),that is crucial for tumor growth.

20 Jan 2010

Radiology Regional Center initiates participation in SOMO•INSIGHT Clinical Study

U-Systems announced today that Radiology Regional Center has initiated participation in the SOMO•INSIGHT Clinical Study. The first breast center in Southwest Florida to participate, Radiology Regional Center is recruiting participants for the national clinical research study designed to evaluate whether digital mammography in combination with the somo•v™ Automated Breast Ultrasound System (ABUS) from U-Systems is more sensitive to detecting breast lesions when compared to Mammography alone in women with dense breasts.

20 Jan 2010

PTC Therapeutics initiates additional clinical trial of ataluren in boys and young men with nmDBMD

PTC Therapeutics, Inc. (PTC) today announced the initiation of an additional clinical trial of ataluren (PTC124®) in boys and young men with nonsense mutation Duchenne/Becker muscular dystrophy (nmDBMD) who have permanently lost the ability to walk independently.

20 Jan 2010

Prenatal exposure to PBDEs associated with neurodevelopmental effects in young children

Prenatal exposure to ambient levels of flame retardant compounds called polybrominated diphenyl ethers (PBDEs) is associated with adverse neurodevelopmental effects in young children, according to researchers at the Columbia Center for Children's Environmental Health (CCCEH) at Columbia University's Mailman School of Public Health.

20 Jan 2010

Zeshaan A. Rasheed receives the 2010 Pancreatic Cancer Action Network-AACR Pathway to Leadership Grant

The Pancreatic Cancer Action Network and the American Association for Cancer Research have awarded Zeshaan A. Rasheed, M.D., Ph.D., the 2010 Pancreatic Cancer Action Network-AACR Pathway to Leadership Grant.

20 Jan 2010

Antibiotics can reduce infections post-Caesarean section

Having a baby by Caesarean section is becoming increasingly common, despite the higher risks associated with the surgery compared to a vaginal birth. One important concern is the risk of infection, which is between five and 20 times greater for women who undergo scheduled or emergency Caesarean section.

20 Jan 2010

Cardiac RSR test can quickly and accurately detect the presence of S-CAD

Testing a patient's cardiac respiratory stress response (RSR) can quickly and accurately detect the presence of significant coronary artery disease (S-CAD), according to new research published in the current issue of Cardiovascular Revascularization Medicine.

20 Jan 2010

Motivational interviewing may help people to quit smoking

Addressing tobacco use without judging the user appears to help people quit, especially if a primary care physician uses a form of supportive counseling called "motivational interviewing," according to a new review of studies.

20 Jan 2010

Health IT roundup: Sharing data, tracking medical errors and revealing costs

The Wall Street Journal: The Journal's Informed Patient column reports that the "non-profit Institute for Safe Medication Practices, which is certified by the federal government to collect error reports and other information about quality breaches, and the American Society of Health-System Pharmacists are launching a new National Alert Network for Serious Medication Errors."

20 Jan 2010

Children from low SES environment may be at risk for numerous health problems in future

It's no surprise that children from low socioeconomic backgrounds may be at risk for numerous health problems in the future. Scientists speculate that these health problems, including increased risk for depression, anxiety and substance abuse, arise from the physiological toll that the environment has on the children's bodies.

20 Jan 2010

Ericson Manufacturing supports breast cancer research and community outreach projects

In 2010 Ericson Manufacturing Company will make significant strides in the support of national breast cancer awareness through a new partnership with Susan G. Komen for the Cure®, the world’s largest breast cancer advocacy organization.

20 Jan 2010

Epidemiologic characteristics of young age GC patients vary by age and gender

Two percent to fifteen percent of patients with gastric cancer (GC) are younger than 45 years of age and there has been an increase in the relative proportion of young age GC compared with older age GC, especially in young females.

20 Jan 2010

Fc engineering enhances antibody half-life

A Nature Biotechnology article published online January 17 reveals that Xencor Inc.’s proprietary Fc engineering extends the half-life of antibodies while maintaining their potency and extending duration of action. These results, published in an article entitled, “Enhanced antibody half-life improves in vivo activity” demonstrate the potential of Fc engineering to impact the flexibility of route, schedule and dose for nearly any antibody.

20 Jan 2010

Scientists discover Ebola's immune evasion strategies

A research team led by Gaya Amarasinghe, an assistant professor of biochemistry, biophysics and molecular biology, had previously solved the structure of a critical part of an Ebola protein known as VP35, which is involved in host immune suppression.

20 Jan 2010

GEH, Exelon Generation agree to a landmark deal to deploy GEH’s isotope generation technology

Seeking to address a growing demand for the domestic and global supply of cobalt-60, a radioisotope used for treating cancer and other biomedical applications, GE Hitachi Nuclear Energy (GEH) and Exelon Generation Company have agreed to a landmark deal to deploy GEH’s isotope generation technology.

20 Jan 2010

Obama seeks elusive health care victory by months' end

President Barack Obama has plenty of reasons to hope Congress has completed its health overhaul debate by the end of the month, including: the just-scheduled State of the Union address on Jan. 27, a Feb. 1 deadline for submitting the 2011 federal budget to Congress, and flagging poll numbers.

20 Jan 2010

Finding supports modularity of mind theory

Recognizing faces is an important social skill, but not all of us are equally good at it. Some people are unable to recognize even their closest friends (a condition called prosopagnosia), while others have a near-photographic memory for large numbers of faces.

20 Jan 2010

U.S. gastroenterologists to treat hepatitis C patients with telaprevir

Decision Resources, one of the world's leading research and advisory firms for pharmaceutical and healthcare issues, finds that U.S. gastroenterologists will treat a larger proportion of treatment nonresponder hepatitis C patients with Vertex/Tibotec/Mitsubishi Tanabe's telaprevir than Merck's boceprevir.

20 Jan 2010

Research News and Research

HSF1A stimulates more protein chaperones and reduces protein misfolding

Officials debate merits of medical marijuana as coping tool in pain fight

Researchers show how gliomas can evade drugs aimed at blocking EGFR

Radiology Regional Center initiates participation in SOMO•INSIGHT Clinical Study

PTC Therapeutics initiates additional clinical trial of ataluren in boys and young men with nmDBMD

Prenatal exposure to PBDEs associated with neurodevelopmental effects in young children

Zeshaan A. Rasheed receives the 2010 Pancreatic Cancer Action Network-AACR Pathway to Leadership Grant

Antibiotics can reduce infections post-Caesarean section

Cardiac RSR test can quickly and accurately detect the presence of S-CAD

Motivational interviewing may help people to quit smoking

Health IT roundup: Sharing data, tracking medical errors and revealing costs

Children from low SES environment may be at risk for numerous health problems in future

Ericson Manufacturing supports breast cancer research and community outreach projects

Epidemiologic characteristics of young age GC patients vary by age and gender

Fc engineering enhances antibody half-life

Scientists discover Ebola's immune evasion strategies

GEH, Exelon Generation agree to a landmark deal to deploy GEH’s isotope generation technology

Obama seeks elusive health care victory by months' end

Finding supports modularity of mind theory

U.S. gastroenterologists to treat hepatitis C patients with telaprevir

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