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New drug combination may offer better prognosis for children diagnosed with deadly brain cancer

Researchers at the University of Colorado Anschutz Medical Campus have discovered a drug combination that may offer a better prognosis for children diagnosed with MYC amplified Medulloblastoma, an often deadly form of brain cancer.

13 Jan 2023

Researchers to evaluate benefits of diet interventions in older adults with $2.1 million NIH grant

Maintaining a healthy weight during the golden years is a priority for many older adults. While previous research has shown that cutting calories can lower disease risk factors, it's unclear whether it can have a long-term positive impact on disease and disability.

12 Jan 2023

Study reveals how inflammation alters the tumor microenvironment in acute myeloid leukemia

Severe inflammation weakens the body's ability to kill cancerous blood cells in people with acute myeloid leukemia (AML), a new study shows.

11 Jan 2023

Simple method increases the efficacy of T cell therapy by cytokine conjugation

The recent years have seen a wave of adoptive cell therapies (ACTs), a type of immunotherapy in which T cells (T cell transfer therapy) and other immune cells are obtained from patients, activated and multiplied outside the body, and infused in larger numbers back into the blood circulation to help fight cancers.

11 Jan 2023

Researchers demonstrate the role of Klotho protein in the formation of osteoarthritis

Researchers in the United States and Japan have discovered a new mechanism that links age-related cartilage tissue stiffening with the repression of a key protein associated with longevity.

10 Jan 2023

Researchers unravel how embryonic cells sense their mechanical environment

Building tissues and organs is one of the most complex and important tasks that cells must accomplish during embryogenesis.

5 Jan 2023

New dual-action, cancer-killing vaccine tested in an advanced mouse model of glioblastoma

Scientists are harnessing a new way to turn cancer cells into potent, anti-cancer agents. In the latest work from the lab of Khalid Shah, MS, PhD, at Brigham and Women's Hospital, a founding member of the Mass General Brigham healthcare system, investigators have developed a new cell therapy approach to eliminate established tumors and induce long-term immunity, training the immune system so that it can prevent cancer from recurring.

4 Jan 2023

Is platelet-rich plasma therapy beneficial in treating chronic respiratory disease?

Researchers conducted a literature review to determine whether platelet-rich plasma therapy could help slow disease progression through lung regeneration in patients with chronic respiratory disease.

4 Jan 2023

Two NIH-supported diets earn five No. 1 spots in in “Best Diets” report

Two National Institute of Health-supported diets, Dietary Approaches to Stop Hypertension (DASH) and Therapeutic Lifestyle Changes (TLC), together earned five No. 1 spots in U.S. News & World Report's 2023 "Best Diets" rankings.

3 Jan 2023

Insulin-like peptide 3 may be a predictor of hypogonadism and age-associated morbidity in older males

Researchers evaluated whether insulin-like peptide 3 (INSL3) could predict hypogonadism and age-associated morbidity in older males.

3 Jan 2023

Study suggests a strategy for preventing the progression of chronic leukemia to aggressive disease

A study from Washington University School of Medicine in St. Louis suggests a strategy for preventing a chronic, slow-growing type of blood cancer from progressing to an aggressive form of leukemia.

29 Dec 2022

Researchers unravel how cells use their sense of touch to make decisions during embryogenesis

A research team at the Cluster of Excellence Physics of Life of TU Dresden and the University of California, Santa Barbara, reveals how cells sense their mechanical environment as they build tissues during embryogenesis.

28 Dec 2022

Microscopy techniques reveal a trail of destruction in bone collagen caused by high energy X-rays

A team of medical researchers at Charité has analyzed damage by focused high energetic X-rays in bone samples from fish and mammals at BESSY II.

22 Dec 2022

Partial knee arthroplasty yields faster functional recovery than total knee replacement

For selected patients with knee osteoarthritis, unicompartmental (or "partial") knee arthroplasty (UKA) shortens the recovery time for two key measures of physical function, as compared with total knee arthroplasty (TKA), reports a randomized trial in The Journal of Bone & Joint Surgery.

22 Dec 2022

3D neutron tomography reveals water diffusion across the bone material

What keeps bones able to remodel themselves and stay healthy? A team from Charité Berlin has discovered clues to the key function of non-collagen protein compounds and how they help bone cells react to external load.

22 Dec 2022

Recapitulating early stages of the human body plan in a dish

Although Michelangelo's masterpiece David captured the magnificence of the human body - how this exquisite body plan is exactly established during human development has puzzled scientists for more than a century.

21 Dec 2022

Research could pave way for designing more strategically engineered transplants to treat cartilage damage in the joints

A collaborative team, which includes scientists from the Terasaki Institute for Biomedical Innovation, University of Illinois Chicago, and Pohang University of Science and Technology has elucidated some key points on how the generation of cartilage in the joints is facilitated and how alternative bone formation can be avoided.

21 Dec 2022

Experts provide first framework for treating hypercalcemia of malignancy in adults

Experts provide the first framework for treating a common and life-threatening metabolic complication of cancer known as hypercalcemia of malignancy in the Endocrine Society's new Clinical Practice Guideline.

21 Dec 2022

Enzyme inhibition reduces cancer-related bone loss and the number of bone metastases

In our bones, specialized cells called osteoblasts are responsible for building up bone substance. A team of researchers led by scientists from the DKFZ-Hector Cancer Institute at the University Medical Center Mannheim and the University Medical Center Hamburg Eppendorf has now identified an enzyme that controls the activity of osteoblasts.

20 Dec 2022

Study highlights the lag in screening and treatment of osteoporosis

A new perspective article published in the Lancet Diabetes & Endocrinology has highlighted that screening and treatment of osteoporosis lags behind other diseases, resulting in significant morbidity, mortality, and economic costs.

20 Dec 2022

Bone News and Research

New drug combination may offer better prognosis for children diagnosed with deadly brain cancer

Researchers to evaluate benefits of diet interventions in older adults with $2.1 million NIH grant

Study reveals how inflammation alters the tumor microenvironment in acute myeloid leukemia

Simple method increases the efficacy of T cell therapy by cytokine conjugation

Researchers demonstrate the role of Klotho protein in the formation of osteoarthritis

Researchers unravel how embryonic cells sense their mechanical environment

New dual-action, cancer-killing vaccine tested in an advanced mouse model of glioblastoma

Is platelet-rich plasma therapy beneficial in treating chronic respiratory disease?

Two NIH-supported diets earn five No. 1 spots in in “Best Diets” report

Insulin-like peptide 3 may be a predictor of hypogonadism and age-associated morbidity in older males

Study suggests a strategy for preventing the progression of chronic leukemia to aggressive disease

Researchers unravel how cells use their sense of touch to make decisions during embryogenesis

Microscopy techniques reveal a trail of destruction in bone collagen caused by high energy X-rays

Partial knee arthroplasty yields faster functional recovery than total knee replacement

3D neutron tomography reveals water diffusion across the bone material

Recapitulating early stages of the human body plan in a dish

Research could pave way for designing more strategically engineered transplants to treat cartilage damage in the joints

Experts provide first framework for treating hypercalcemia of malignancy in adults

Enzyme inhibition reduces cancer-related bone loss and the number of bone metastases

Study highlights the lag in screening and treatment of osteoporosis

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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