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American Gastroenterological Association announces 2019 recipients of annual recognition awards

The American Gastroenterological Association (AGA) has announced the 2019 recipients of the annual recognition awards, given in honor of outstanding contributions and achievements in gastroenterology.

4 Feb 2019

New class of antisense oligonucleotide therapeutics tested in humans

A first-in-human study with a new class of antisense oligonucleotide therapeutics showed the ability to target the RNA-silencing drug to the liver, resulting in improved potency and safety at therapeutic doses. The design and results of this trial, conducted in healthy human volunteers are reported in Nucleic Acid Therapeutics, a peer-reviewed journal from Mary Ann Liebert, Inc. publishers.

28 Jan 2019

Targeting Sirt-1 enzyme shows promise in controlling graft-vs-host disease

Bone marrow transplant offers patients with leukemia and lymphoma a potentially curative treatment. Bone marrow from the donor contains healthy immune cells, whose mission is to protect the body from invaders.

28 Jan 2019

Regular use of aspirin may help some patients survive head and neck cancer

Regular use of aspirin or other nonsteroidal anti-inflammatory drugs may help some patients with head and neck cancer survive the disease, according to a study led by Professor Jennifer Grandis at the University of California, San Francisco.

27 Jan 2019

NIH researchers discover that anti-flu antibodies can inhibit two different viral proteins

Researchers from the National Institutes of Health have discovered that antibodies that may form the basis of a universal flu vaccine inhibit a second viral protein in addition to the one that they bind.

25 Jan 2019

Researchers discover new details of brain pathway related to impulsive behaviors

Researchers from Singapore and South Korea have uncovered new details of a brain pathway that can cause impulsive behaviors.

25 Jan 2019

Researcher identifies putative mechanism that leads to degeneration of axons in multiple sclerosis

The permanent neurological deficits of multiple sclerosis patients largely depend on the extent of degeneration of long nerve fibers. The latter is initiated by ruptures in the cell membrane and the resulting influx of calcium ions.

25 Jan 2019

Cellular recycling process may prevent cancer initiation, finds study

Just as plastic tips protect the ends of shoelaces and keep them from fraying when we tie them, molecular tips called telomeres protect the ends of chromosomes and keep them from fusing when cells continually divide and duplicate their DNA.

24 Jan 2019

Researchers design interleukin protein to balance overshooting immune response

Small infections can be fatal: Millions of people die each year from sepsis, an overreaction of the immune system.

23 Jan 2019

INTEGRA offers new 24-channel pipetting heads for VIAFLO 96/384 to make cell culture easy

INTEGRA has responded to customers’ requests and developed two new 24-channel pipetting heads, extending the capabilities of its popular VIAFLO 96/384.

From INTEGRA Biosciences 23 Jan 2019

Study offers new hope for elimination of malaria

After major global successes in the battle against malaria, the positive trend stalled around 2015 - apart from in Zanzibar in East Africa, where only a fraction of the disease remains.

22 Jan 2019

Mouse studies challenge 'inhibition' theory of autism

A detailed study of four mouse models of autism challenges the most common assumption about what goes wrong in brain circuits to cause disease symptoms.

21 Jan 2019

Researchers demonstrate how manganese produces parkinsonian syndrome

Using X-ray fluorescence at synchrotrons DESY and ESRF, researchers in the Centre d'Etudes Nucléaires de Bordeaux Gradignan have demonstrated the consequences of a mutation responsible for a hereditary parkinsonian syndrome: accumulated manganese in the cells appears to disturb protein transport.

16 Jan 2019

LifeTime receives fund to develop a plan to embed its vision for healthier future

Our body's cells are constantly changing. But which of these changes are healthy developments and which lead to serious diseases? This is what LifeTime, a new transnational and interdisciplinary initiative of leading European researchers, aims to discover.

16 Jan 2019

Scientists reveal key mechanism in worms that controls cell's response to stress

Scientists have revealed a key mechanism in worms that is involved in controlling the cell's response to stress, a study in eLife reports.

16 Jan 2019

FDA-approved drug hampers cancer metastasis in animal model, shows study

For cancer to spread, it needs a hospitable environment in distant organs. This fertile "soil" can provide a home to circulating malignant cells.

16 Jan 2019

New evidence shows how fever alters immune cells

Fever is known to help power up our immune cells, and scientists in Shanghai have new evidence explaining how.

16 Jan 2019

Scientists identify endogenous activator of sigma-1 receptors in human cells

Cells communicate through complex mechanisms that typically involve receptors and ligands that bind to them. Endogenous ligands, produced by the body, have been identified for the vast majority of cellular receptors, helping explain receptor existence and function. But in the case of sigma-1 receptors, which interact with a diverse array of psychoactive drugs, an endogenous ligand has remained elusive.

14 Jan 2019

UCR researchers uncover how plants sense temperature

When it gets hot outside, humans and animals have the luxury of seeking shelter in the shade or cool, air-conditioned buildings. But plants are stuck.

14 Jan 2019

New discovery casts doubt on plasma membrane models

Like planets, the body's cell surfaces look smooth from a distance but hilly closer up. An article published in Communications Biology describes implications, unknown to date, of the way data from cell surfaces are normally interpreted; i.e. as if they lacked topographic features.

14 Jan 2019