Metastasis News and Research

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Metastasis is the spread of cancer from one part of the body to another. A tumor formed by cells that have spread is called a “metastatic tumor” or a “metastasis.” The metastatic tumor contains cells that are like those in the original (primary) tumor. The plural form of metastasis is metastases

Elevated levels of particular proteins in cancer cells fuel growth and spread of different cancers

Researchers at University of California, San Diego School of Medicine and Moores Cancer Center, with colleagues in Spain and Germany, have unraveled how elevated levels of particular proteins in cancer cells trigger hyperactivity in other proteins, fueling the growth and spread of a variety of cancers.

27 Feb 2016

BCRF expands research program with new collaborative breast cancer funding model

The Breast Cancer Research Foundation announced the expansion of its research program with a new collaborative breast cancer funding model—the BCRF Investigator-Initiated Drug Research Program—that will help broaden and accelerate clinical research on treatment strategies for people with breast cancer.

22 Feb 2016

Scientists find that lifespan of supportive cells in tumor may control cancer metastasis

Researchers have discovered that eliminating cells thought to aid tumor growth did not slow or halt the growth of cancer tumors. In fact, when the cancer-associated fibroblasts (CAFs), were eliminated after 10 days, the risk of metastasis of the primary tumor to the lungs and bones of mice increased dramatically.

22 Feb 2016

Kellogg investigators develop new nanotechnology that has potential to kill tumor cells in the eye

Researchers at the University of Michigan Kellogg Eye Center have developed a new nanoparticle that uses a tumor cell's protective mechanism against itself -- short-circuiting tumor cell metabolism and killing tumor cells.

19 Feb 2016

Mtss1 'tumour suppressor' for CML

The metastasis suppressor 1 protein acts a tumour suppressor in chronic myeloid leukaemia stem cells, reveals research published in Leukemia.

17 Feb 2016

FAU researchers find mechanism that promotes metastasis and causes tumours to resist treatment

Fast metastasis and resistance to treatment are characteristic of aggressive types of cancer such as pancreatic cancer and certain kinds of breast cancer. They are also the main causes of cancer-related death, as there is currently no specific treatment available that is able to stop tumours spreading throughout the whole body. Researchers at Friedrich-Alexander-Universität Erlangen-Nürnberg have recently made a discovery that could change this.

17 Feb 2016

Researchers discover factor that controls embryonic stem cell development

After a gestation period of around ten months, fawns are born in early summer - when the weather is warm and food is plentiful for the mother. Six months would actually be enough for the embryo's development, but then offspring from mating in the later portion of summer would be born in winter.

17 Feb 2016

New staging system proposed to identify most appropriate treatments for HPV-related OPC

Human papillomavirus (HPV) status is a strong predictor of prognosis for patients with oropharyngeal carcinoma (OPC), but the current staging system does not adequately account for biological and clinical differences between HPV-positive OPC and HPV-negative OPC, commonly caused by alcohol and tobacco use.

17 Feb 2016

Neural gene promotes growth and spread of metastatic breast cancer

When breast cancer becomes advanced and spreads to other organs, patient survival is drastically reduced, prompting the need to explore the genes that may cause tumor cells to metastasize.

15 Feb 2016

MGH study reveals effects of obesity on pancreatic and breast cancer

Massachusetts General Hospital investigators may have uncovered a novel mechanism behind the ability of obesity to promote cancer progression. In their report published online in the journal Clinical Cancer Research, the research team describes finding an association between obesity and an overabundance of a factor called PlGF (placental growth factor) and that PlGF's binding to its receptor VEGFR-1, which is expressed on immune cells within tumors, promotes tumor progression.

12 Feb 2016

Natural extract from India's neem tree shows promise against pancreatic cancer

A natural extract derived from India's neem tree could potentially be used to treat pancreatic cancer, according to a new study in the journal Scientific Reports.

12 Feb 2016

Scientists propose use of mathematical models to find better treatment for bladder cancer

MIPT scientists together with their colleagues from St. Petersburg and Israel have analyzed more than 500 previously published scientific articles and proposed their own approach to the choice of methods used for the treatment of one of the most common cancers.

11 Feb 2016

Small minority of cancer cells contribute to growth and metastasis of tumours

New research shows that a small minority of cancer cells in neuroendocrine tumours of the pancreas contribute to the overall growth and metastasis of the tumour. This discovery was made by a research group at Lund University, in collaboration with researchers at Karolinska Institutet, in Sweden.

3 Feb 2016

'Junk' DNA suppresses breast cancer

Supposed "junk" DNA, found in between genes, plays a role in suppressing cancer, according to new research by Universities of Bath and Cambridge.

2 Feb 2016

Study provides new insights into breast cancer metastasis

It has long been thought that cancer metastasizes, or spreads, when a single cancer cell escapes from the original tumor, travels through the bloodstream and sets up shop in distant organs. However, a growing body of evidence suggests that these bad actors don't travel alone; instead they migrate through the body in cellular clusters, like gangs.

2 Feb 2016

Rockland announces availability of new human melanoma cell lines

Rockland Immunochemicals, Inc. announces the availability of a new collection of human melanoma cell lines that have been developed and characterized over several decades in the laboratory of Meenhard Herlyn, D.V.M., D.Sc., Caspar Wistar Professor in Melanoma Research, Director of the Melanoma Research Center, and professor in the Molecular and Cellular Oncogenesis Program at The Wistar Institute in Philadelphia.

1 Feb 2016

VARI-SU2C Epigenetics Dream Team supports new clinical trial that targets metastatic colorectal cancer

The first clinical trial to move forward as part of the Van Andel Research Institute-Stand Up To Cancer (VARI-SU2C) Epigenetics Dream Team will target metastatic colorectal cancer, the second leading cause of cancer deaths among men and women combined in the U.S.

29 Jan 2016

Metastasis News and Research

Further Reading

Elevated levels of particular proteins in cancer cells fuel growth and spread of different cancers

BCRF expands research program with new collaborative breast cancer funding model

Scientists find that lifespan of supportive cells in tumor may control cancer metastasis

Kellogg investigators develop new nanotechnology that has potential to kill tumor cells in the eye

Mtss1 'tumour suppressor' for CML

FAU researchers find mechanism that promotes metastasis and causes tumours to resist treatment

Researchers discover factor that controls embryonic stem cell development

New staging system proposed to identify most appropriate treatments for HPV-related OPC

Neural gene promotes growth and spread of metastatic breast cancer

MGH study reveals effects of obesity on pancreatic and breast cancer

Natural extract from India's neem tree shows promise against pancreatic cancer

Scientists propose use of mathematical models to find better treatment for bladder cancer

Small minority of cancer cells contribute to growth and metastasis of tumours

'Junk' DNA suppresses breast cancer

Study provides new insights into breast cancer metastasis

Rockland announces availability of new human melanoma cell lines

VARI-SU2C Epigenetics Dream Team supports new clinical trial that targets metastatic colorectal cancer

AVAX announces results of Phase 1/2 OVAX study in patients with advanced ovarian cancer

Researchers explore ways to use light to combat cancer

Researchers identify biomarkers that may influence potential new drug design or alternative treatments of cancer

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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