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OHSU Cancer Institute research gives hope for chemo holidays for men with advanced prostate cancer

Oregon Health & Science University Cancer Institute researchers, in a first-of-its-kind study, have found that even men with advanced prostate cancer can take a much-needed safe break, or holiday, from chemotherapy.

27 Feb 2008

Mechanism of blood clot elasticity revealed in high definition

Blood clots can save lives, staunching blood loss after injury, but they can also kill. Let loose in the bloodstream, a clot can cause a heart attack, stroke or pulmonary embolism.

26 Feb 2008

High zinc status in lung cells slows growth and induces DNA

Researchers at the University of Maryland at College Park have discovered that Normal Human Bronchial Epithelial (NHBE) cells cultured in medium with elevated zinc level, at the high end of plasma zinc attainable by oral supplementation, demonstrated inhibition of cell growth, up-regulation of growth arrest and DNA damage-induced gene (Gadd45) mRNA and protein expression, and blockage of G2/M cell cycle progression.

26 Feb 2008

New gene discovered that determines hair texture and density in humans

A Columbia University Medical Center research team has discovered a new gene involved in determining hair texture in humans.

26 Feb 2008

Abbott receives approval for HUMIRA (Adalimumab) for polyarticular juvenile idiopathic arthritis

Abbott has announced that it has received U.S. Food and Drug Administration (FDA) approval to market HUMIRA (adalimumab) as a treatment to reduce signs and symptoms of moderately to severely active polyarticular juvenile idiopathic arthritis (JIA) in patients four years of age and older.

26 Feb 2008

Small protein discovered that specifically recognizes tumors responding to chemotherapy

A technique that specifically "tags" tumors responding to chemotherapy may offer a new strategy for determining a cancer treatment's effectiveness within days of starting treatment, according to a new study by Vanderbilt-Ingram Cancer Center investigators.

26 Feb 2008

New large-scale method reveals drug targets

Wellcome Trust Sanger Institute scientists have developed a new large-scale method to identify the interactions between proteins that are a major target for therapeutic intervention.

26 Feb 2008

Notch protein plays a critical role in bone formation

Notch, a protein known to govern the determination of cell differentiation into different kinds of tissues in embryos, plays a critical role in bone formation and strength later in life, said researchers from Baylor College of Medicine in Houston in a report that appears online today in the journal Nature Medicine.

26 Feb 2008

Powerful new cell research tool

The view into the inner world of living cells just got a little brighter and more colorful.

26 Feb 2008

Hair loss breakthrough

A healthy individual loses around a hundred hairs a day. Nothing to worry about as long as they are constantly replaced and the losses occur evenly around the whole scalp.

26 Feb 2008

New discovery on how gene-regulatory networks govern metabolism

Metabolism is a central feature of life - a myriad of biochemical processes that, together, enable organisms to nourish and sustain themselves.

26 Feb 2008

Novel hMSH2 gene mutation in colorectal cancer patients

About 20% of colorectal cancer (CRC) patients have a genetic component and HNPCC is the most common autosomal dominant hereditary syndrome.

25 Feb 2008

Newly discovered ERK pathway proteins related to CagA induced disease

Cytotoxin-associated gene A protein (CagA) from type I H.pylori has been proved by epidemiological and experimental studies to be closely associated with the H.pylori induced gastric diseases, especially gastric cancer.

25 Feb 2008

XYNTHA approved for teatment of hemophilia A by FDA

Wyeth Pharmaceuticals, a division of Wyeth ( NYSE:WYE) , announced today that it has received approval from the U.S. Food and Drug Administration for XYNTHA(TM) (Antihemophilic Factor [Recombinant], Plasma/Albumin-Free), a recombinant factor VIII product, for patients with hemophilia A for both the control and prevention of bleeding episodes and surgical prophylaxis.

22 Feb 2008

New understanding of how big molecules bind will lead to better drugs, synthetic organic materials

Biological and medical research is on the threshold of a new era based on better understanding of how large organic molecules bind together and recognise each other.

22 Feb 2008

Curcumin reduces heart enlargement and may prevent heart failure

Eating curcumin, a natural ingredient in the spice turmeric, may dramatically reduce the chance of developing heart failure, researchers at the Peter Munk Cardiac Centre of the Toronto General Hospital have discovered.

22 Feb 2008

New proof-of-principle findings that thymic involution can be reversed in humans

Scientists at the Gladstone Institute of Virology and Immunology (GIVI) and the University of California, San Francisco (UCSF) have found that therapy can be used to stimulate the production of vital immune cells, called "T- cells," in adults with HIV infection.

21 Feb 2008