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EPFL scientists create gold nanoparticles to combat all viruses

HIV, dengue, papillomavirus, herpes and Ebola - these are just some of the many viruses that kill millions of people every year, mostly children in developing countries. While drugs can be used against some viruses, there is currently no broad-spectrum treatment that is effective against several at the same time, in the same way that broad-spectrum antibiotics fight a range of bacteria.

18 Dec 2017

Researchers identify mechanism that regulates signaling events leading to cancer metastasis

Understanding how cancer cells are able to metastasize -- migrate from the primary tumor to distant sites in the body -- and developing therapies to inhibit this process are the focus of many laboratories around the country.

18 Dec 2017

Mature cells also play role in initiating cancer, study suggests

Rapidly dividing, yet aberrant stem cells are a major source of cancer. But a new study suggests that mature cells also play a key role in initiating cancer - a finding that could upend the way scientists think about the origin of the disease.

18 Dec 2017

Study provides insights on factors that affect quality of life in older cancer patients

A new study provides insights on the factors that affect health-related quality of life in older adults with cancer. Published early online in CANCER, a peer-reviewed journal of the American Cancer Society, the findings support the importance of addressing persistent symptoms, managing comorbidities, promoting leisure-time physical activity, and addressing financial challenges.

18 Dec 2017

Excessive copper in diabetes impedes ability to make new blood vessels

It's a metal we worry thieves will steal from our air conditioners or power lines, but inside our bodies too much copper can result in a much larger loss.

18 Dec 2017

Diabetes patients least likely to follow medical advice regarding medication due to side effects

Diabetes patients who take the most commonly prescribed diabetes drug, metformin, are the least likely to follow medical advice regarding their medication due its side effects, a new article in the journal Diabetes, Obesity and Metabolism reports.

18 Dec 2017

Gene that could be associated with reduced pain response found

Researchers found an Italian family, the Marsilis that have six individuals who respond significantly differently to pain than others. This includes a 78-year-old lady and her two daughters and their three children.

18 Dec 2017

Ketamine can stop suicidal thoughts finds new study

A study has shown that Ketamine – an anesthetic drug, is capable of reducing and halting suicidal thoughts in depressed patients. The study comes from Columbia University Medical Center (CUMC) who found that it may take only a few hours after administration of ketamine to reduce the suicidal thoughts in the patients.

18 Dec 2017

Tobacco safer when “heated not burnt” say manufacturers – health panel unconvinced

Tobacco companies now say that tobacco is safer when “heated not burned”. A government advisory body has negated these claims saying that even heated, tobacco containing products have chemicals that can cause serious harm to health.

17 Dec 2017

HKBU experts develop new generation of smart anti-cancer drug molecules

The toxic nature of chemotherapy poses a great challenge to clinical treatment of cancer. A team of scholars from the School of Chinese Medicine of Hong Kong Baptist University devoted their efforts to the development of a new generation of smart anti-cancer drug molecules.

15 Dec 2017

Prostate cancer researchers find significant disparities between two liquid biopsy providers

Two Johns Hopkins prostate cancer researchers found significant disparities when they submitted identical patient samples to two different commercial liquid biopsy providers.

15 Dec 2017

Scientists use nanoparticles to fight Mucoviscidosis

Scientists of the Friedrich Schiller University Jena, Germany succeeded in developing an efficient method to treat Mucoviscidosis. Crucial are nanoparticles that transport the antibiotics more efficiently to their destination.

15 Dec 2017

Kaiser Permanente delivers clot-busting drugs to stroke patients more than twice as fast as national rates

Kaiser Permanente hospitals in Northern California are delivering clot-busting medication to new stroke patients more than twice as fast as the national average. This follows the regionwide adoption of an integrated telemedicine program, according to new research published Dec. 15 in the journal Stroke.

15 Dec 2017

Rejected antibiotic candidate could be worth a second look, research finds

An antibiotic candidate compound shelved in the 1970s in favour of more worthwhile drugs could be worth a second look, new research has found.

15 Dec 2017

Chronic Kidney Disease Audit finds wide variations in coding of CKD patients in primary care

Sustainability and Transformation Partnerships, Clinical Commissioning Groups and primary care practices must all work together to improve outcomes for patients with Chronic Kidney Disease (CKD), according to the national Chronic Kidney Disease Audit published today.

15 Dec 2017

‘Sushi-like’ nanodiscs provide structural snapshots of misfolding proteins

When proteins misfold, accumulate and clump around insulin-producing cells in the pancreas, they kill cells. Now, researchers, including University of Michigan biophysicists, have obtained a structural snapshot of these proteins when they are most toxic, detailing them down to the atomic level.

15 Dec 2017

Researchers examine human mutations' impact on therapeutic effect of medicine

Every person has a unique DNA sequence in their genome. Now researchers from the University of Copenhagen and the MRC Laboratory of Molecular Biology in Cambridge have tried to quantify what these differences in the genome mean in the context of the genes targeted by drugs.

15 Dec 2017

Researchers explore how toxic protein clusters linked to Parkinson's disrupt brain cells

Researchers have glimpsed how the toxic protein clusters that are associated with Parkinson's Disease disrupt the membranes of healthy brain cells, creating defects in the cell walls and eventually causing a series of events that induce neuronal death.

15 Dec 2017

Cancer immunotherapy’s effectiveness may depend on patient’s genetic makeup

Cancer cells arise when DNA is mutated, and these cells should be recognized as "foreign" by the immune system. However, cancer cells have found ways to evade detection by the immune system.

15 Dec 2017

Rare gene mutation gives rise to low sensitivity to pain

Researchers at University College London have identified a rare gene mutation in an Italian family who have little sensitivity to some forms of pain. Chronic pain caused by conditions such as lower back pain and osteoarthritis is one of the most prominent causes of disability worldwide, as assessed by the Global Burden of Disease reviews.

15 Dec 2017

Drugs News and Research

EPFL scientists create gold nanoparticles to combat all viruses

Researchers identify mechanism that regulates signaling events leading to cancer metastasis

Mature cells also play role in initiating cancer, study suggests

Study provides insights on factors that affect quality of life in older cancer patients

Excessive copper in diabetes impedes ability to make new blood vessels

Diabetes patients least likely to follow medical advice regarding medication due to side effects

Gene that could be associated with reduced pain response found

Ketamine can stop suicidal thoughts finds new study

Tobacco safer when “heated not burnt” say manufacturers – health panel unconvinced

HKBU experts develop new generation of smart anti-cancer drug molecules

Prostate cancer researchers find significant disparities between two liquid biopsy providers

Scientists use nanoparticles to fight Mucoviscidosis

Kaiser Permanente delivers clot-busting drugs to stroke patients more than twice as fast as national rates

Rejected antibiotic candidate could be worth a second look, research finds

Chronic Kidney Disease Audit finds wide variations in coding of CKD patients in primary care

‘Sushi-like’ nanodiscs provide structural snapshots of misfolding proteins

Researchers examine human mutations' impact on therapeutic effect of medicine

Researchers explore how toxic protein clusters linked to Parkinson's disrupt brain cells

Cancer immunotherapy’s effectiveness may depend on patient’s genetic makeup

Rare gene mutation gives rise to low sensitivity to pain

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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