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Experts tell Congress how to cut drug prices

The nation's most influential science advisory group will tell Congress today that the U.S. pharmaceutical market is not sustainable and needs to change.

12 Dec 2017

Researchers identify promising solution for improving cystic fibrosis treatments

Researchers at the University of Montreal Hospital Research Centre have identified a promising solution to improving treatments offered to patients with cystic fibrosis.

12 Dec 2017

Novel compound inhibits mycomembrane biosynthesis and kills tuberculosis bacteria

Tuberculosis is one of the most widespread life-threatening infectious diseases. Not only does antibiotic resistance make treatment increasingly difficult, but the bacteria’s relatively impermeable mycomembrane also limits the effectiveness of many drugs.

12 Dec 2017

Hidden genes hold blueprints for designing new anti-cancer drugs

New research suggests these hidden genes hold the blueprints for designing new, even more effective cancer-targeting compounds.

12 Dec 2017

An overlooked epidemic: Older Americans taking too many unneeded drugs

Consider it America’s other prescription drug epidemic. For decades, experts have warned that older Americans are taking too many unnecessary drugs, often prescribed by multiple doctors, for dubious or unknown reasons.

12 Dec 2017

Researchers find new role for SHARPIN protein in melanoma growth

Researchers at Sanford Burnham Prebys Medical Discovery and the Technion in Israel have found a new role for the SHARPIN protein. In addition to being one of three proteins in the linear ubiquitin chain assembly complex, regulating NFκB and other inflammatory molecules, SHARPIN modulates PRMT5, an epigenetic master switch that controls several proteins linked to melanoma. The research was published in The Journal of Clinical Investigation.

12 Dec 2017

First short-acting ‘follow-on’ insulin receives FDA approval to treat diabetes

The U.S. Food and Drug Administration today approved Admelog (insulin lispro injection), a short-acting insulin indicated to improve control in blood sugar levels in adults and pediatric patients aged 3 years and older with type 1 diabetes mellitus and adults with type 2 diabetes mellitus.

12 Dec 2017

Study: Combination targeted therapy has high response rates in AML patients

Initial findings from a multi-national open-label phase Ib study of inhibitory drug therapy for relapsed or refractory acute myeloid leukemia (AML) have demonstrated a complete response in up to 50 percent patients say researchers at The University of Texas MD Anderson Cancer Center.

11 Dec 2017

Genentech researchers uncover epigenetic regulator of pancreatic cancer cells

Genentech researchers have identified an enzyme that shifts pancreatic cancer cells to a more aggressive, drug-resistant state by epigenetically modifying the cells' chromatin.

11 Dec 2017

Researchers identify potential alternatives to tackle drug resistant malaria parasites

A new analysis of all relevant previously published clinical data shows how parasites causing malaria become resistant to a commonly used treatment for malaria in travellers.

11 Dec 2017

Russian researchers create new approaches to prevention and treatment of diabetes

A team of scientists from the Ural Federal University and the Institute of Immunology and Physiology modeled type 1 diabetes in an experiment to study recovery processes in the pancreas.

11 Dec 2017

Death receptors in the blood can help measure risk of cardiovascular diseases, type 2 diabetes

Researchers at Lund University in Sweden have found that the presence of death receptors in the blood can be used to directly measure the risk of developing cardiovascular diseases and type 2 diabetes.

11 Dec 2017

WSU scientists create injectable dye to track progression of diseases

Washington State University scientists have created an injectable dye that illuminates molecules with near infrared light, making it easier to see what is going on deep inside the body.

11 Dec 2017

Researchers generate 3D cell cultures to investigate mechanisms of drug resistance in breast cancer

An international research team headed by the University of Bern and the Netherlands Cancer Institute has developed 3D cell cultures in which genes can be specifically modified. They allow the study of genes that may cause therapy resistance in breast cancer.

11 Dec 2017

Pairing immunotherapy drug with chemotherapy proves beneficial for relapsed acute myeloid leukemia

University of North Carolina Lineberger Comprehensive Cancer Center researchers report that pairing an immunotherapy drug with chemotherapy proved beneficial for some patients with acute myeloid leukemia whose disease did not respond to standard treatment or had relapsed.

11 Dec 2017

Opioids after surgery left her addicted. Is that a medical error?

In April this year, Katie Herzog checked into a Boston teaching hospital for what turned out to be a nine-hour-long back surgery.

11 Dec 2017

Combination of chemotherapy and targeted drug improves response in younger CLL patients

Among younger patients newly diagnosed with chronic lymphocytic leukemia (CLL), treatment with a combination of chemotherapy and a molecularly targeted drug significantly improves response over what is typically seen with chemotherapy alone, according to an investigator-initiated multi-center phase II clinical trial.

11 Dec 2017

Two immunotherapy approaches for multiple myeloma show hope

Researchers from the University of Pennsylvania's Abramson Cancer Center have developed two experimental immunotherapy methods that include one chimeric antigen receptor (CAR) T cell therapy for the treatment of multiple myeloma patients who were not responding to other treatments.

11 Dec 2017

Generic versions of Viagra coming this week

Drug manufacturer Pfizer is coming up with a cheaper and generic version of their erectile dysfunction pill Viagra this week.

10 Dec 2017

SLU scientists provide promising approach in designing new drugs for DMD

In a paper published in the Nature journal Scientific Reports, Saint Louis University researchers report that a new drug reduces fibrosis (scarring) and prevents loss of muscle function in an animal model of Duchenne muscular dystrophy (DMD), providing a promising approach in designing new medications for those suffering from DMD.

8 Dec 2017

Drugs News and Research

Experts tell Congress how to cut drug prices

Researchers identify promising solution for improving cystic fibrosis treatments

Novel compound inhibits mycomembrane biosynthesis and kills tuberculosis bacteria

Hidden genes hold blueprints for designing new anti-cancer drugs

An overlooked epidemic: Older Americans taking too many unneeded drugs

Researchers find new role for SHARPIN protein in melanoma growth

First short-acting ‘follow-on’ insulin receives FDA approval to treat diabetes

Study: Combination targeted therapy has high response rates in AML patients

Genentech researchers uncover epigenetic regulator of pancreatic cancer cells

Researchers identify potential alternatives to tackle drug resistant malaria parasites

Russian researchers create new approaches to prevention and treatment of diabetes

Death receptors in the blood can help measure risk of cardiovascular diseases, type 2 diabetes

WSU scientists create injectable dye to track progression of diseases

Researchers generate 3D cell cultures to investigate mechanisms of drug resistance in breast cancer

Pairing immunotherapy drug with chemotherapy proves beneficial for relapsed acute myeloid leukemia

Opioids after surgery left her addicted. Is that a medical error?

Combination of chemotherapy and targeted drug improves response in younger CLL patients

Two immunotherapy approaches for multiple myeloma show hope

Generic versions of Viagra coming this week

SLU scientists provide promising approach in designing new drugs for DMD

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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