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Researchers identify new subgroup of cervical cancers with different genetic features

A team of University of South Carolina scientists led by Carolyn Banister and Phillip Buckhaults has identified a new subtype of cervical cancer that, like most cervical cancers, is triggered by human papillomavirus (HPV) but whose growth is not directed by the virus, suggesting that therapy targeting these tumors' distinct genomic pathways may improve patient outcomes over standard treatment.

11 Jan 2017

NCI launches new drug formulary to help expedite use of agents in clinical studies

The National Cancer Institute today launched a new drug formulary (the "NCI Formulary") that will enable investigators at NCI-designated Cancer Centers to have quicker access to approved and investigational agents for use in preclinical studies and cancer clinical trials.

11 Jan 2017

Surveillance machinery in cells recognizes and destroys defective genetic material, research shows

New research out of Case Western Reserve University School of Medicine describes a mechanism by which an essential quality control system in cells identifies and destroys faulty genetic material. The findings were published online December 23 in Nature Communications.

11 Jan 2017

'Dementia gene' may offer protection against cognitive decline linked to parasitic diseases

New research published online in The FASEB Journal, suggests that carriers of the Apolipoprotein E4 allele, which is the single strongest genetic predictor of Alzheimer's disease and is associated with cognitive decline and cardiovascular disease, may have a reduced risk of cognitive decline associated with parasitic diseases.

11 Jan 2017

MGH researchers identify gene mutations linked to rare congenital condition involving lack of nose

Researchers from Massachusetts General Hospital led a large, international research team that has identified gene mutations associated with a rare congenital condition involving the absence of a nose and often accompanied by defects involving the eye and reproductive systems.

11 Jan 2017

Mayo Clinic scientists identify key molecule that helps protect the central nervous system against sepsis

No effective therapy exists today for sepsis, an inflammatory storm that afflicts about 3 million Americans a year - killing up to half.

10 Jan 2017

Archaeologist discovers 800-year-old genomes from bacterial infection in Byzantine skeleton

Eight hundred years ago, in a hardscrabble farming community on the outskirts of what was once one of the fabled cities of the ancient world, Troy, a 30-year-old woman was laid to rest in a stone-lined grave.

10 Jan 2017

Sedentary older adults likely to develop dementia as those with genetic risk factors, research finds

Sedentary older adults with no genetic risk factors for dementia may be just as likely to develop the disease as those who are genetically predisposed, according to a major study which followed more than 1,600 Canadians over five years.

10 Jan 2017

Penn State researchers develop novel compound to combat cytomegalovirus

A Retro94-based compound may prevent a common and sometimes fatal virus -- human cytomegalovirus (CMV) -- from reproducing and help to protect immunocompromised patients, such as those with HIV, on chemotherapy, with transplants, and infants from the effects of the disease, according to Penn State College of Medicine researchers.

10 Jan 2017

Cocaine addicts make riskier decisions than healthy people after losing potential reward

People addicted to cocaine make riskier decisions than healthy people after losing a potential reward, according to a study published in Biological Psychiatry: Cognitive Neuroscience and Neuroimaging.

10 Jan 2017

KIT researchers prove that neurons regulate blood vessel growth

A team of researchers at Karlsruhe Institute of Technology shake at the foundations of a dogma of cell biology.

10 Jan 2017

Appendix may serve as reservoir for beneficial gut bacteria, new research suggests

The human appendix, a narrow pouch that projects off the cecum in the digestive system, has a notorious reputation for its tendency to become inflamed (appendicitis), often resulting in surgical removal.

10 Jan 2017

Researchers find high-resolution structure of immature Zika virus

Researchers at Purdue University have determined the high-resolution structure of immature Zika virus, a step toward better understanding how the virus infects host cells and spreads.

10 Jan 2017

Scientists crack genetic code to identify men at risk for prostate cancer that spreads after treatment

Canadian prostate cancer researchers have discovered the genetic fingerprint that explains why up to 30 per cent of men with potentially curable localized prostate cancer develop aggressive disease that spreads following radiotherapy or surgery.

10 Jan 2017

IRB Barcelona researchers disclose new signal involved in growth of fly wings

Many of the secrets of life, such as how we become a certain size and shape, have been uncovered in studies performed over more than 100 years and involving animal models such as the fruit fly Drosophila melanogaster.

10 Jan 2017

Johns Hopkins researchers identify new biological target for treating spinal muscular atrophy

Johns Hopkins researchers along with academic and drug industry investigators say they have identified a new biological target for treating spinal muscular atrophy.

9 Jan 2017

Research shows that education plays smaller role in delaying motherhood among UK women

Studies have suggested that over recent decades, UK women have postponed motherhood largely because they want to go onto college or university to gain qualifications or fulfil educational aspirations before starting a family.

9 Jan 2017

HUB and Dutch health insurance companies to test use of organoid technology for CF treatment

Hubrecht Organoid Technology (HUB), and the health insurance companies CZ, Zilveren Kruis, and Menzis announced today that they will start a €3 million validation trial for use of HUB Organoid Technology to test if it can be used to determine the response of Cystic Fibrosis (CF) patients to new drug therapies.

9 Jan 2017

Thought leaders at U-CARS meeting to explore issues related to heart recovery and regeneration

For many years, the answer to that question was unequivocally "No." But as the University of Utah School of Medicine's annual Utah Cardiac Recovery Symposium will explore on Jan. 12-13, advances in treating heart failure are giving physicians, surgeons and researchers reason to hope the deadly disease might one day be defeated.

6 Jan 2017

ATA releases new guidelines for diagnosis, treatment of thyroid disease during pregnancy and postpartum

New evidence-based recommendations from the American Thyroid Association provide guidance to clinicians in diagnosing and managing thyroid disease during pregnancy and the postpartum period.

6 Jan 2017

Genetic News and Research

Researchers identify new subgroup of cervical cancers with different genetic features

NCI launches new drug formulary to help expedite use of agents in clinical studies

Surveillance machinery in cells recognizes and destroys defective genetic material, research shows

'Dementia gene' may offer protection against cognitive decline linked to parasitic diseases

MGH researchers identify gene mutations linked to rare congenital condition involving lack of nose

Mayo Clinic scientists identify key molecule that helps protect the central nervous system against sepsis

Archaeologist discovers 800-year-old genomes from bacterial infection in Byzantine skeleton

Sedentary older adults likely to develop dementia as those with genetic risk factors, research finds

Penn State researchers develop novel compound to combat cytomegalovirus

Cocaine addicts make riskier decisions than healthy people after losing potential reward

KIT researchers prove that neurons regulate blood vessel growth

Appendix may serve as reservoir for beneficial gut bacteria, new research suggests

Researchers find high-resolution structure of immature Zika virus

Scientists crack genetic code to identify men at risk for prostate cancer that spreads after treatment

IRB Barcelona researchers disclose new signal involved in growth of fly wings

Johns Hopkins researchers identify new biological target for treating spinal muscular atrophy

Research shows that education plays smaller role in delaying motherhood among UK women

HUB and Dutch health insurance companies to test use of organoid technology for CF treatment

Thought leaders at U-CARS meeting to explore issues related to heart recovery and regeneration

ATA releases new guidelines for diagnosis, treatment of thyroid disease during pregnancy and postpartum

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Evaluating new approaches for rare disease genomics

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