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Complete new skin from transgenic stem cells for boy with rare genetic disease

Hassan, a then seven-year-old boy from Germany, in 2015, presented to the doctors with a rare skin disease called junctional epidermolysis bullosa or JEB. This condition leaves the skin thin and papery and easily breakable. It has been compared to “butterfly wings” because of their fragile nature.

8 Nov 2017

Orthocell earns CE Mark approval for CelGro collagen medical device

Regenerative medicine company Orthocell Limited is pleased to announce receipt of European regulatory approval (CE Mark) for its CelGro collagen medical device.

8 Nov 2017

New gene therapy trial for X-linked myotubular myopathy offers hope to children

Ann & Robert H. Lurie Children's Hospital of Chicago is one of the few centers participating in ASPIRO, an international Phase 1/2 clinical trial of a gene therapy product called AT132 for X-linked myotubular myopathy – a rare disease characterized by severe muscle weakness, breathing difficulty and early death.

8 Nov 2017

Leg ulcers may heal faster with exercise, study suggests

A preliminary British Journal of Dermatology study suggests that ulcers in the legs may heal faster with exercise.

8 Nov 2017

Research: Prognosis for people with diabetic foot ulcers worse than previously thought

The prognosis for people with an infected diabetic foot ulcer is worse than was previously thought, according to new research.

8 Nov 2017

Discontinuation of hormone therapy linked to increased risk of cardiac, stroke death

Hormone therapy continues to be a hotly debated topic. The benefits of estrogen to the heart, however, appear to be universally accepted.

8 Nov 2017

Early intervention may be crucial to successful treatment of Friedreich's ataxia

New research published today in Disease Models & Mechanisms indicates that early intervention should be a key target in the development of new therapeutics for Friedreich's ataxia, as current treatments may be administered too late to target the disease effectively.

8 Nov 2017

UNIGE neuroscientists succeed in correcting activity of late neurons

During the fetal stage, millions of neurons are born in the walls of the ventricles of the brain before migrating to their final location in the cerebral cortex.

8 Nov 2017

New category of immunotherapy appears safe to use in patients with both cancer and HIV

A new category of immunotherapies called checkpoint inhibitors that has been highly effective against many different cancers appears safe to use in patients with both advanced malignancies and HIV, a population excluded from earlier trials of such therapies, according to an early-phase trial.

7 Nov 2017

Stem cells could help improve blood circulation in diabetic patients with peripheral artery disease

Stem cells taken from muscle tissue could promote better blood flow in patients with diabetes who develop peripheral artery disease, a painful complication that can require surgery or lead to amputation.

7 Nov 2017

Australia’s annual report on STIs shows increasing rates of gonorrhea and syphilis

Cases of gonorrhea and syphilis are increasing in Australia, according to the most recent Annual Surveillance Report on HIV, viral hepatitis and sexually transmissible infections (STIs) in Australia.

7 Nov 2017

Popular Alzheimer's drug shows promise in clinical trials for treating patients with sickle cell disease

A popular drug commonly used to treat Alzheimer's disease has shown promise in laboratory and clinical trials for treating patients with sickle cell disease (SCD).

7 Nov 2017

High protein diet may have deleterious long-term impact on kidney health

High protein diets may lead to long-term kidney damage among those suffering from chronic kidney disease, according to research led by nephrologist Kamyar Kalantar-Zadeh, MD, MPH, PhD, of the University of California, Irvine.

7 Nov 2017

Texas Biomedical Research Institute tests promising new treatment for HBV infection

Research at the Southwest National Primate Research Center on the campus of Texas Biomedical Research Institute helped advance a new treatment now in human trials for chronic hepatitis B virus (HBV) infection.

7 Nov 2017

Researchers to test use of ‘viral specific’ T-cells to target toxic viruses in children

Michael Pulsipher, MD, of the Children's Center for Cancer and Blood Diseases at Children's Hospital Los Angeles, along with Michael Keller, MD from Children's National Health System in Washington, DC, have been awarded $4.8 million by the California Institute for Regenerative Medicine to study the use of a new T-cell therapy to help fight active viral infections in children with severe immune deficiencies.

7 Nov 2017

FDA approves first targeted cancer treatment based on basket study

The US Food and Drug Administration has announced that it has approved the drug vemurafenib for the treatment of patients with BRAF V600-mutant Erdheim-Chester disease (ECD).

7 Nov 2017

FDA grants approval to first treatment for rare blood cancer

The U.S. Food and Drug Administration today expanded the approval of Zelboraf (vemurafenib) to include the treatment of certain adult patients with Erdheim-Chester Disease (ECD), a rare cancer of the blood.

7 Nov 2017

Common antidepressants may not work for depressed patients with chronic kidney disease

Scientists are finding more evidence that commonly prescribed antidepressants aren't effective in people battling both depression and a chronic medical disease, raising a critical question of whether doctors should enact widespread changes in how they treat millions of depressed Americans.

7 Nov 2017

FDA approves new drug Zelboraf for Erdheim-Chester disease

The United States Food and Drugs Administration (FDA) has approved Zelboraf (vemurafenib), a drug for the treatment of adults with a are type of blood cancer called Erdheim-Chester Disease or ECD.

6 Nov 2017

ORBITA trial on heart stents for stable angina indicates placebo effect potential

A new study conducted by researchers at the Imperial College London suggests that the placebo effect experienced by patients who receive coronary artery stents might be larger than expected, even though stents themselves are life-saving.

6 Nov 2017

Therapy News and Research

Complete new skin from transgenic stem cells for boy with rare genetic disease

Orthocell earns CE Mark approval for CelGro collagen medical device

New gene therapy trial for X-linked myotubular myopathy offers hope to children

Leg ulcers may heal faster with exercise, study suggests

Research: Prognosis for people with diabetic foot ulcers worse than previously thought

Discontinuation of hormone therapy linked to increased risk of cardiac, stroke death

Early intervention may be crucial to successful treatment of Friedreich's ataxia

UNIGE neuroscientists succeed in correcting activity of late neurons

New category of immunotherapy appears safe to use in patients with both cancer and HIV

Stem cells could help improve blood circulation in diabetic patients with peripheral artery disease

Australia’s annual report on STIs shows increasing rates of gonorrhea and syphilis

Popular Alzheimer's drug shows promise in clinical trials for treating patients with sickle cell disease

High protein diet may have deleterious long-term impact on kidney health

Texas Biomedical Research Institute tests promising new treatment for HBV infection

Researchers to test use of ‘viral specific’ T-cells to target toxic viruses in children

FDA approves first targeted cancer treatment based on basket study

FDA grants approval to first treatment for rare blood cancer

Common antidepressants may not work for depressed patients with chronic kidney disease

FDA approves new drug Zelboraf for Erdheim-Chester disease

ORBITA trial on heart stents for stable angina indicates placebo effect potential

Advancing Neuroscience Research Through Collaboration and Patient-Centered Innovation

The impact of vibration on microscopy

How Omics Technologies Are Transforming Biological Research and Drug Discovery

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