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BUSM professor receives Ellison Foundation grant to explore new Parkinson's disease target

Richard Myers, PhD, professor of neurology at Boston University School of Medicine, was recently awarded $100,000 from the Ellison Foundation for research to further study a Parkinson's disease (PD) target.

4 Jan 2017

Study shows new role of zinc in optic nerve injury

For more than two decades, researchers have tried to regenerate the injured optic nerve using different growth factors and/or agents that overcome natural growth inhibition.

3 Jan 2017

Study provides vital clues into biology of gambling addiction

Gambling addiction activates the same brain pathways as drug and alcohol cravings, suggests new research.

3 Jan 2017

Researchers develop first non-human primate X-SCID models using genome editing techniques

Researchers affiliated with the Kawasaki INnovation Gateway at SKYFRONT, have successfully generated the first ever non-human primate X-SCID models by using two genome editing techniques. The findings were published in Cell Stem Cell, July 2016.

3 Jan 2017

NIH researchers identify molecular mechanisms that may underlie woman's susceptibility to PMDD

National Institutes of Health researchers have discovered molecular mechanisms that may underlie a woman's susceptibility to disabling irritability, sadness, and anxiety in the days leading up to her menstrual period.

3 Jan 2017

Genes influencing social communication skills linked to genes underlying psychiatric disorders

The researchers studied the genetic overlap between the risk of having these psychiatric disorders and measures of social communicative competence - the ability to socially engage with other people successfully - during middle childhood to adolescence.

3 Jan 2017

Biological Psychiatry special issue highlights role of dopamine signaling in schizophrenia

Biological Psychiatry presents a special issue, "The Dopamine Hypothesis of Schizophrenia", dedicated to recent advances in understanding the role of dopamine signaling in schizophrenia.

2 Jan 2017

AAV-based gene therapy to treat liver disorders advances into human testing

Liver-directed gene therapy delivered using adeno-associated viral (AAV) vectors to treat diseases such as hemophilia have advanced into human testing.

30 Dec 2016

Study examines how ApoE gene may function differently in infectious environment

You've likely heard about being in the right place at the wrong time, but what about having the right genes in the wrong environment? In other words, could a genetic mutation (or allele) that puts populations at risk for illnesses in one environmental setting manifest itself in positive ways in a different setting?

30 Dec 2016

Researchers identify possible treatment targets for myelodysplasia syndromes

Cincinnati Children's researchers report in Nature Immunology a new mechanism that controls blood cell function and several possible molecular targets for treating myelodysplasia syndromes (MDS) - a group of pre-malignant disorders in which bone marrow does not produce enough healthy blood cells.

30 Dec 2016

Zymo Research offers new sample collection devices that contain DNA/RNA Shield reagent

Zymo Research announced today that it is offering five new sample collection devices. Each type of collection tube contains Zymo Research's DNA/RNA Shield™ storage reagent, which preserves the genetic integrity and expression profiles of various samples such as cells, tissues, blood, plasma, serum, saliva, urine, and feces, at ambient temperatures for extended periods.

30 Dec 2016

A new strategy to fight prostate cancer

A new study led by scientists from the Florida campus of The Scripps Research Institute (TSRI) sheds light on a signaling circuit in cells that drives therapy resistance in prostate cancer.

30 Dec 2016

New molecular imaging technologies can make it easier to treat cancers, minimize side effects

New molecular imaging technologies can make it easier to diagnose, monitor, and treat cancers while potentially saving patients from undergoing therapies that are likely to be ineffective and playing a role in minimizing side effects, according to experts from the Abramson Cancer Center and the Perelman School of Medicine at the University of Pennsylvania.

30 Dec 2016

New diet could treat pediatric patients with Crohn's disease, ulcerative colitis

In a first-of-its-kind study published today in the Journal of Clinical Gastroenterology, researchers from Seattle Children's and Children's Healthcare of Atlanta, led by Dr. David Suskind, a Seattle Children's gastroenterologist, found that diet alone can bring pediatric patients with active Crohn's disease and ulcerative colitis (UC) into clinical remission.

30 Dec 2016

Mutations linked to endometrial cancer can be found in uterine lavage fluid before cancer diagnosis

Mutations that have been linked to endometrial cancer can be found in the uterine lavage fluid of pre- and post-menopausal women both with and without detectable cancer, according to a study published in PLOS Medicine by John Martignetti, MD, PhD of the Icahn School of Medicine at Mount Sinai and colleagues.

30 Dec 2016

New tool explains how proteins assemble into different liquid and gel-like solid states

A tool that uses light to manipulate matter inside living cells has begun to explain how proteins assemble into different liquid and gel-like solid states, a key to understanding many critical cellular operations.

30 Dec 2016

Genetic and environmental factors affect language-related brain activities

Osaka University-led researchers examine brain activity in monozygotic and dizygotic Japanese twins and show that environmental and genetic influences affect language-related brain activities in left frontal area of the brain.

30 Dec 2016

Studies in non-human primates provide more predictive results in genetic causes of blindness

Many gene therapy-based approaches are in development to combat genetic and other causes of blindness and vision loss, and much can be learned about the safety and effectiveness of these promising new therapies by studying them first in non-human primates before initiating clinical trials, as shown by the results of a study published in Human Gene Therapy, a peer-reviewed journal from Mary Ann Liebert, Inc., publishers.

29 Dec 2016

Phase I study of selumetinib drug shows partial response in pediatric neural tumors

In an early-phase clinical trial of a new oral drug, selumetinib, children with the common genetic disorder neurofibromatosis type 1 (NF1) and plexiform neurofibromas, tumors of the peripheral nerves, tolerated selumetinib and, in most cases, responded to it with tumor shrinkage.

29 Dec 2016

Fred Hutch’s new Evergreen Fund to promote commercialization of research into lifesaving therapies

Fred Hutchinson Cancer Research Center announced its first-ever grants from its newly established Evergreen Fund to spur researchers' efforts to advance bold ideas toward creating or partnering with a commercial entity.

28 Dec 2016

Genetic News and Research

BUSM professor receives Ellison Foundation grant to explore new Parkinson's disease target

Study shows new role of zinc in optic nerve injury

Study provides vital clues into biology of gambling addiction

Researchers develop first non-human primate X-SCID models using genome editing techniques

NIH researchers identify molecular mechanisms that may underlie woman's susceptibility to PMDD

Genes influencing social communication skills linked to genes underlying psychiatric disorders

Biological Psychiatry special issue highlights role of dopamine signaling in schizophrenia

AAV-based gene therapy to treat liver disorders advances into human testing

Study examines how ApoE gene may function differently in infectious environment

Researchers identify possible treatment targets for myelodysplasia syndromes

Zymo Research offers new sample collection devices that contain DNA/RNA Shield reagent

A new strategy to fight prostate cancer

New molecular imaging technologies can make it easier to treat cancers, minimize side effects

New diet could treat pediatric patients with Crohn's disease, ulcerative colitis

Mutations linked to endometrial cancer can be found in uterine lavage fluid before cancer diagnosis

New tool explains how proteins assemble into different liquid and gel-like solid states

Genetic and environmental factors affect language-related brain activities

Studies in non-human primates provide more predictive results in genetic causes of blindness

Phase I study of selumetinib drug shows partial response in pediatric neural tumors

Fred Hutch’s new Evergreen Fund to promote commercialization of research into lifesaving therapies

eBook: Using iPSCs models for human disease research and drug discovery eBook

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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