Hormones News and Research

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FDA extends indication of metastatic breast cancer treatment to include male patients

The U.S. Food and Drug Administration today is extending the indication of Ibrance (palbociclib) capsules in combination with specific endocrine therapies for hormone receptor (HR)-positive, human epidermal growth factor receptor 2 (HER2)-negative advanced or metastatic breast cancer in male patients.

5 Apr 2019

Researchers synthesize new polysulfide donor that has high anti-inflammatory effect

Researchers from Japan have developed a new polysulfide donor: a chemical compound composed of chains of sulfur atoms that can artificially increase reactive sulfur species (chemically reactive molecules containing sulfur) in cells and tissues.

4 Apr 2019

Researchers uncover gender differences in reports of adverse drug reactions

In a British Journal of Clinical Pharmacology study, investigators uncovered numerous gender differences in reports of adverse drug reactions sent to the National Pharmacovigilance Centre in the Netherlands.

3 Apr 2019

Compounds derived from common hop plant thwart cancer cells

The plant that adds flavor, color and bitterness to beer also produces a primary compound that thwarts cancer cells, and two important derivatives of the compound do as well, new research at Oregon State University shows.

3 Apr 2019

Household dust may be contributing to childhood obesity epidemic

New research has found that chemicals found in household dust may promote fat cell development and contribute to increased weight gain in children.

1 Apr 2019

Allergic reactions trigger changes in brain behavior development in unborn males and females

Researchers at the University of Maryland School of Medicine and colleagues at Ohio State University have discovered that allergic reactions trigger changes in brain behavior development in unborn males and females.

29 Mar 2019

New discovery may explain low testosterone levels in men with diabetes

Scientists have mapped out how the body transports testosterone, and their surprising findings may explain low testosterone levels seen in men with diabetes or patients on certain medications.

28 Mar 2019

Contraceptive jewelry may be new approach to family planning for women

Family planning for women might one day be as simple as putting on an earring.

27 Mar 2019

Male contraceptive pill crosses the human clinical trial hurdle

Birth control pills have been around for the past six decades but have been for use of women only. A team of researchers this week have announced the success of the first male birth control pill that could safely prevent pregnancy.

27 Mar 2019

Male contraceptive pill shown to be safe and tolerable in phase I trial

A potential new male birth control pill has been declared safe for use after a phase I trial showed that the once-daily capsule works without causing any significant side effects.

26 Mar 2019

Higher levels of sex hormones in older men related to lower biological age

Older men tend to have lower biological age if they have higher levels of sex hormones, particularly the estradiol form of estrogen, a large new study from Australia finds.

26 Mar 2019

Sleep quality varies throughout menstrual cycle in young women

Young women are more likely to experience sleep disruption in the days leading up to their menstrual period, according to a new study that will be presented Saturday at ENDO 2019, the annual meeting of the Endocrine Society, in New Orleans, La.

25 Mar 2019

Obesity linked to reproductive problems in women with type 1 diabetes

Obesity may play a role in reproductive problems in women with type 1 diabetes, according to a new study to be presented Saturday, March 23 at ENDO 2019, the Endocrine Society's annual meeting in New Orleans, La.

25 Mar 2019

Recurrent pregnancy loss may be caused by sperm DNA damage, finds study

Some cases of recurrent pregnancy loss may be caused by sperm DNA damage in the male partner, rather than by a problem in affected women, according to research to be presented Sunday, March 24 at ENDO 2019, the Endocrine Society's annual meeting in New Orleans, La.

25 Mar 2019

Long term opioid medications impacts production of important hormones

Many people who use opioid medications long term do not produce enough testosterone or another important hormone, cortisol, according to a new study.

25 Mar 2019

BPA exposure during pregnancy can lead to changes in circadian rhythms

Exposure to the widely used chemical bisphenol A during pregnancy, even at levels lower than the regulated "safe" human exposure level, can lead to changes in circadian rhythms, according to a mice study to be presented Monday at ENDO 2019, the Endocrine Society's annual meeting in New Orleans, La. The researchers report these changes may be a contributing factor in hyperactivity seen in BPA-exposed mice.

25 Mar 2019

Lian wins ENGINE grant for stem-cell-based therapy to treat Type 1 diabetes

Xiaojun "Lance" Lian, assistant professor of biomedical engineering, was one of three recipients of the College of Engineering's ENGineering for Innovation & Entrepreneurship grant for "Small Molecule-Based Definitive Endoderm Kit and Pancreatic Progenitor Kit for Stem Cell Research and Therapy."

22 Mar 2019

European Parliament's report calls on EU to develop policies to regulate endocrine-disrupting chemicals

The Endocrine Society applauded the European Parliament's release of a report demonstrating that endocrine-disrupting chemicals pose a serious threat to the health of current and future generations and illustrating the need for additional action by policymakers in the EU to address this issue.

21 Mar 2019

FDA approves brexanolone, first drug developed to treat postpartum depression

Approximately 1 in 9 women in the United States experiences symptoms of postpartum depression, according to the Centers for Disease Control and Prevention.

21 Mar 2019

Androgen receptor plays vital role in regulating multiple mitochondrial processes

Androgens, commonly known as male hormones, stimulate prostate cancer cells to grow. Thus, many of the drugs to target that cancer focus on stopping androgen biosynthesis or blocking the androgen receptor. This standard treatment is known as androgen deprivation therapy.

20 Mar 2019