Liver Cancer News and Research

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Liver cancer is more common in older people. Over half of people newly diagnosed with liver cancer are age 65 and over. Liver cancer is more common in men than in women. Liver cancer rates are highest among Asians and Pacific Islanders, most likely because of higher prevalence of viral Hepatitis infection. Liver cancer rates are lower among whites than Blacks or Asians and Pacific Islanders. At this time, we do not know exactly what causes cancer of the liver. There are several different types of liver cancer. The most common type is associated with long-term excessive alcoholic beverage use, scarring of the liver (cirrhosis), and Hepatitis B virus or Hepatitis C virus infection. Long-term use of anabolic steroids can also increase the risk of getting liver cancer. Smoking is also believed to increase the risk of getting liver cancer.

Epidemiologic characteristics of young age GC patients vary by age and gender

Two percent to fifteen percent of patients with gastric cancer (GC) are younger than 45 years of age and there has been an increase in the relative proportion of young age GC compared with older age GC, especially in young females.

20 Jan 2010

Need for further studies on clinical characteristics of Intrahepatic Cholangiocarcinoma

Incidence of intrahepatic cholangiocarcinoma (ICC) is increasing worldwide and its prognosis is very poor. Thus, further studies on its clinical characteristics for early detection and on surgical treatment for better prognosis are urgently needed.

18 Jan 2010

Research article examining the use of acupuncture to prevent PPOI published

A research article to be published on January 7 , 2010 in the World Journal of Gastroenterology addresses this question. In this prospective randomized clinical trial, the authors examined if acupuncture could prevent prolonged postoperative ileus (PPOI) after intraperitoneal surgery among patients with colon cancer in Shanghai, China.

18 Jan 2010

New insights into molecular interaction between probiotics and altered host intestinal ecosystem in IPAA

Total proctocolectomy with ileal J-pouch-anal anastomosis (IPAA) is the surgical treatment of choice for patients with refractory ulcerative colitis (UC). Although the surgery generally cures UC allowing a significant improvement of health-related quality of life, complications can occur after IPAA.

18 Jan 2010

Hyperphosphatemia following standard OSP doses is related to weight, reveals study

Colon cleansing is used widely for colonoscopic exploration and colonic and gynecological surgery. Oral sodium phosphate (OSP) solution is the osmotic laxative most commonly used for this purpose. It is known that OSP can induce severe hyperphosphatemia and hypocalcemia due to excessive absorption of phosphates, and there have been reports of deaths and irreversible dialysis-requiring renal insufficiency. However, no prospective studies have investigated the prevalence of hyperphosphatemia in low-risk patients.

18 Jan 2010

Research team reports rare etiology of SMA syndrome

Diabetes mellitus is one of the most common chronic disease of the world and the prevalence of diabetes mellitus is over 10% in Taiwan. Gastroparesis is reported in 5% to 12% of diabetic patients.

18 Jan 2010

Regulus Therapeutics presents new data on oncology, immune disease and HCV therapeutic programs

Regulus Therapeutics Inc. today announced that new pre-clinical data from multiple therapeutic programs were presented at the “RNA Silencing: Mechanism, Biology and Application” Keystone Symposium held January 14 – 19, 2010 in Keystone, Colorado. Regulus and its collaborators presented data showing microRNA target regulation by anti-miRs, as well as data from therapeutic programs focused on oncology, immune disease and hepatitis C virus (HCV) infection.

18 Jan 2010

Research article addressing incidental findings in MRI-enterography in patients with CD to be published

MRI is increasingly used in the assessment of small bowel CD. Unlike conventional radiology, MRI enables visualization of disease extension beyond the intestinal wall, i.e., abscesses and fistulas. However, some extra-intestinal findings are unexpected and without relation to CD.

18 Jan 2010

Geisinger CEO wins 2010 TRUST Award

The Health Research & Educational Trust (HRET), an affiliate of the American Hospital Association (AHA), has selected Glenn D. Steele Jr., MD, PhD president and chief executive officer of Geisinger Health System, as the recipient of the 2010 TRUST Award.

18 Jan 2010

Alterations in intestinal microbiota may lie behind IBS aetiology

Irritable bowel syndrome (IBS) is a common gastrointestinal functional disorder that can greatly affect the patient's well being. Multiple interacting mechanisms, including alterations in the intestinal microbiota, are suspected to lie behind IBS aetiology.

18 Jan 2010

Results show neoadjuvant chemoradiotherapy improves patients with EC

Esophageal carcinoma (EC) is one of the major malignant diseases worldwide. Surgery alone cannot obtain satisfactory effects in patients with EC. Neoadjuvant chemoradiotherapy has been a hotspot for EC treatment research. Several related randomized controlled trials (RCTs) have been published, but opinions vary among clinicians as to the therapeutic effect of the new method.

18 Jan 2010

Treatment for chronic hepatitis C with pegylated-interferon and ribavirin proves effective

The current standard treatment for chronic hepatitis C with pegylated-interferon (PEG-IFN) and ribavirin is effective in approximately 50%-60% of patients, so that a substantial proportion of patients remain unresponsive.

18 Jan 2010

Role of H. pylori in autoimmune atrophic gastritis

Experimental animal studies have shown that H. pylori shares several antigenic regions in common with acid secreting cells in gastric mucosa. Antibodies triggered by H. pylori destroy acid secreting cells due to this antigenic mimicry.

17 Jan 2010

CT-guided biopsy: An alternative method for patients with pancreatic masses

It is reasonable to obtain a histological diagnosis before treating patients who have pancreatic masses and are unsuitable or unwilling to undergo surgery. As the pancreas is a deep seated organ surrounded by other vital structures, it is a challenge for the physician to obtain an adequate specimen for histological examination.

17 Jan 2010

Studies show treatment success for chronic hepatitis C may be predicted by rapid virological response

The likelihood of treatment success of 48 wk peg-interferon (PEG-IFN) plus ribavirin (RBV) therapy for chronic hepatitis C may be predicted by viral kinetics on therapy. In particular, recent studies have shown that sustained virological response (SVR) can be predicted by a rapid virological response (RVR), and an early virological response (EVR).

17 Jan 2010

Abraxis Bioscience awards John Wayne Cancer Institute $1M grant for identifying new cancer biomarkers

A $1 million grant from Abraxis Bioscience, Inc. to a world-famous research laboratory at John Wayne Cancer Institute at Saint John’s Health Center could help save lives of cancer patients by helping doctors more rapidly assess whether a treatment is working or not.

12 Jan 2010

NVHR supports IOM report on inadequate federal funding for chronic viral hepatitis

With today's release of a landmark study by the Institute of Medicine (IOM), Hepatitis and Liver Cancer: A National Strategy for Prevention and Control of Hepatitis B and C, finding that inadequate public-health resources are being allocated to national and local prevention, control, and surveillance programs, the National Viral Hepatitis Roundtable (NVHR) today renewed its call for the Administration, Congress, and the entire health care system to take immediate and decisive action to implement the report's key recommendations.

12 Jan 2010

4SC commences treatment in its resminostat Phase II trial for HL

4SC AG, a drug discovery and development company focused on autoimmune and cancer indications, today announced the treatment of the first patient in a Phase II study evaluating resminostat (4SC-201), an oral pan-histone-deacetylase (HDAC) inhibitor in relapsed or refractory Hodgkin's Lymphoma (HL) patients.

12 Jan 2010

Public awareness campaign needed to curb health threats posed by hepatitis B and hepatitis C

Stepped-up vaccination requirements, a boost in resources for prevention and treatment, and a public awareness campaign similar to the effort that dispelled the stigma of HIV/AIDS are needed to curb the health threats posed by hepatitis B and hepatitis C, says a new report from the Institute of Medicine.

12 Jan 2010

AASLD supports IOM study that recommends ways to reduce viral hepatitis B and C

The American Association for the Study of Liver Disease (AASLD) today reacted favorably to the release by they Institute of Medicine (IOM) of the report of "Hepatitis and Liver Cancer: A National Strategy for Prevention and Control of Hepatitis B and C." This landmark study evaluated the burden from viral hepatitis and current preventive and management practices and recommended ways to reduce new cases of hepatitis B and C and morbidity and mortality from chronic disease.

11 Jan 2010

Liver Cancer News and Research

Further Reading

Epidemiologic characteristics of young age GC patients vary by age and gender

Need for further studies on clinical characteristics of Intrahepatic Cholangiocarcinoma

Research article examining the use of acupuncture to prevent PPOI published

New insights into molecular interaction between probiotics and altered host intestinal ecosystem in IPAA

Hyperphosphatemia following standard OSP doses is related to weight, reveals study

Research team reports rare etiology of SMA syndrome

Regulus Therapeutics presents new data on oncology, immune disease and HCV therapeutic programs

Research article addressing incidental findings in MRI-enterography in patients with CD to be published

Geisinger CEO wins 2010 TRUST Award

Alterations in intestinal microbiota may lie behind IBS aetiology

Results show neoadjuvant chemoradiotherapy improves patients with EC

Treatment for chronic hepatitis C with pegylated-interferon and ribavirin proves effective

Role of H. pylori in autoimmune atrophic gastritis

CT-guided biopsy: An alternative method for patients with pancreatic masses

Studies show treatment success for chronic hepatitis C may be predicted by rapid virological response

Abraxis Bioscience awards John Wayne Cancer Institute $1M grant for identifying new cancer biomarkers

NVHR supports IOM report on inadequate federal funding for chronic viral hepatitis

4SC commences treatment in its resminostat Phase II trial for HL

Public awareness campaign needed to curb health threats posed by hepatitis B and hepatitis C

AASLD supports IOM study that recommends ways to reduce viral hepatitis B and C

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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