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Finding ways to improve cell replacement therapy for Parkinson's disease

Parkinson's disease is a neurodegenerative disease that affects dopamine signaling neurons in patients' brains. Cell-replacement therapy shows some promise as a treatment for Parkinson's. A recent paper in the journal Molecular & Cellular Proteomics reports a technical advance in selecting cells to use in this therapy.

24 Aug 2018

Study provides new clues to connection between aging and neurodegeneration

For decades researchers have worked to shed light on the causes of neurodegenerative disorders, a group of devastating conditions, including Alzheimer's and Parkinson's, that involve the progressive loss of neurons and nervous system function. In recent years, numerous factors, from genetic mutations to viral infections, have been found to contribute to the development of these diseases.

23 Aug 2018

Study: Motor cortex necessary for movement control in response to unexpected situations

Scientists have demonstrated that the motor cortex is necessary for the execution of corrective movements in response to unexpected changes of sensory input but not when the same movements are executed spontaneously.

23 Aug 2018

New imaging technique allows mapping electrical activity in single neurons

Our brain cells control every aspect of our lives - from the movements we make to the memories we form. But capturing the activity of neurons in the form of electric impulses isn't easy.

23 Aug 2018

Harvard scientists end 40-year-quest for elusive identity of 'hearing' protein

Scientists at Harvard Medical School say they have ended a 40-year-quest for the elusive identity of the sensor protein responsible for hearing and balance.

23 Aug 2018

Single neuron in fruit fly triggers new behavior and also suppresses antagonistic behavior

In the fruit fly, a single pair of brain neurons command backward locomotion in both larvae and adults, researchers report.

23 Aug 2018

Wyss researchers create model of the BBB-brain interface using microfluidically linked Organ Chips

The human brain, with its 100 billion neurons that control every thought, word, and action, is the most complex and delicate organ in the body. Because it needs extra protection from toxins and other harmful substances, the blood vessels that supply the brain with oxygen and nutrients are highly selective about which molecules can cross from the blood into the brain and vice versa.

22 Aug 2018

Researchers discover new subtype of multiple sclerosis

Cleveland Clinic researchers have discovered a new subtype of multiple sclerosis, providing a better understanding of the individualized nature of the disease.

22 Aug 2018

Study shows that rogue proteins may underlie some ALS and frontotemporal dementia cases

ALS -- amyotrophic lateral sclerosis -- is a neurodegenerative disease that attacks motor neurons in the brain and spinal cord, slowly robbing its victims of their ability to walk, talk, breathe and swallow.

20 Aug 2018

Common antidepressant restores significant degree of lost plasticity to aging brain cells in mice

A new study provides fresh evidence that the decline in the capacity of brain cells to change, called "plasticity," rather than a decline in total cell number may underlie some of the sensory and cognitive declines associated with normal brain aging.

20 Aug 2018

Researchers uncover surprising new role for inhibition in the cerebellum

Almost everyone is familiar with the unique mixture of surprise and confusion that occurs after making a mistake during an everyday movement.

17 Aug 2018

Researchers transform research tool to study neuronal function

Puzzled by their experimental results, a team of scientists from Baylor College of Medicine and Texas Children's Hospital investigated why a research tool that was expected to suppress neuronal activity actually was stimulating it.

14 Aug 2018

Autoimmune response drives neurodegeneration in glaucoma

A research team from Massachusetts Eye and Ear and the Massachusetts Institute of Technology has shown that immune cells in the eye that developed in response to early exposure to bacteria are a key contributor to progressive vision loss from glaucoma, the second leading cause of irreversible blindness in the world.

12 Aug 2018

Reduced levels of chaperone protein may have implications for development of Parkinson’s disease

Reduced levels of a chaperone protein might have implications for the development and progression of neurodegenerative diseases such as Parkinson's disease and Lewy body dementia, according to new research from investigators at the University of Alabama at Birmingham.

10 Aug 2018

Autoimmune response contributes to vision loss in glaucoma patients

A research team from Massachusetts Eye and Ear and MIT has shown that immune cells in the eye that developed in response to early exposure to bacteria are a key contributor to progressive vision loss from glaucoma, the second leading cause of irreversible blindness in the world.

10 Aug 2018

Ground-breaking discovery offers new hope for treatment of Alzheimer’s, other neurological diseases

There is new hope for the treatment of Alzheimer’s and other neurological diseases following a ground-breaking discovery made by an Australian-Chinese research collaboration.

10 Aug 2018

Novel discovery offers hope for treatment of Alzheimer's and other neurological diseases

There is new hope for the treatment of Alzheimer's and other neurological diseases following a ground-breaking discovery made by an Australian-Chinese research collaboration.

10 Aug 2018

Researchers discover genetic mutation underlying debilitating childhood brain disorder

Ashleigh Schaffer, PhD, assistant professor of genetics at Case Western Reserve University School of Medicine, and a team of global genetics experts have discovered a genetic mutation and the faulty development process it triggers, causing a debilitating brain-based disorder in children.

9 Aug 2018

Scientists identify key neurobiological mechanisms that control aggression

A number of psychiatric disorders present with aggression and violence, which, needless to say, are destructive to both individuals and societies worldwide: death, disease, disability, and numerous socioeconomic problems can often be traced back to aggressive behavior.

9 Aug 2018

Researchers uncover clues on how the brain separates important from unimportant information

The precise interaction of brain waves and nerve cells may be decisive for the amazing ability of our brain to separate important from unimportant information, even when we are flooded with stimuli.

9 Aug 2018

Neuron News and Research

Finding ways to improve cell replacement therapy for Parkinson's disease

Study provides new clues to connection between aging and neurodegeneration

Study: Motor cortex necessary for movement control in response to unexpected situations

New imaging technique allows mapping electrical activity in single neurons

Harvard scientists end 40-year-quest for elusive identity of 'hearing' protein

Single neuron in fruit fly triggers new behavior and also suppresses antagonistic behavior

Wyss researchers create model of the BBB-brain interface using microfluidically linked Organ Chips

Researchers discover new subtype of multiple sclerosis

Study shows that rogue proteins may underlie some ALS and frontotemporal dementia cases

Common antidepressant restores significant degree of lost plasticity to aging brain cells in mice

Researchers uncover surprising new role for inhibition in the cerebellum

Researchers transform research tool to study neuronal function

Autoimmune response drives neurodegeneration in glaucoma

Reduced levels of chaperone protein may have implications for development of Parkinson’s disease

Autoimmune response contributes to vision loss in glaucoma patients

Ground-breaking discovery offers new hope for treatment of Alzheimer’s, other neurological diseases

Novel discovery offers hope for treatment of Alzheimer's and other neurological diseases

Researchers discover genetic mutation underlying debilitating childhood brain disorder

Scientists identify key neurobiological mechanisms that control aggression

Researchers uncover clues on how the brain separates important from unimportant information

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