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Pioneering research in caves provides new insights into origins of antibiotic resistance

Pioneering work being carried out in a cave in New Mexico by researchers at McMaster University and The University of Akron, Ohio, is changing the understanding of how antibiotic resistance may have emerged and how doctors can combat it in the future.

8 Dec 2016

New mathematical model suggests how AD may progress to become chronic

Successive flare-ups of the most common form of eczema may trigger an immune system overreaction, causing it to become a long-term condition in people.

8 Dec 2016

Researchers developing model to predict breast cancer patient’s response to chemotherapy

University of North Carolina Lineberger Comprehensive Cancer Center researchers and collaborators are working to predict, before treatment, whether an aggressive type of breast cancer will respond to chemotherapy.

8 Dec 2016

Researchers discover biological pathway that plays vital role in tumor development

An international team led by researchers from the Technion-Israel Institute of Technology's Rappaport Faculty of Medicine and the Technion Integrated Cancer Center has discovered a biological pathway that plays an important role in tumor development.

7 Dec 2016

Older women with metastatic breast cancer more likely to have genetic alterations in tumors

A University of North Carolina Lineberger Comprehensive Cancer Center-led analysis has found that women who are 65 years or older with metastatic breast cancer were more likely to have a cancer-linked genetic alterations in their tumors, and had a larger total number of genetic alterations, than younger patients overall.

7 Dec 2016

Pathogenic variants in certain genes increase woman's likelihood of developing breast cancer

Inherited pathogenic variants in protein coding genes BARD1 and RAD51D increase a woman's likelihood of developing breast cancer, according to research conducted at Mayo Clinic and presented today at the 2016 San Antonio Breast Cancer Symposium.

7 Dec 2016

Cold Spring Harbor Laboratory Press publishes new book on key aspects of ciliary biology

Nearly every cell in the human body has one or more protrusive structures called cilia or flagella.

7 Dec 2016

Enzyme that cleaves beta carotene may control testosterone levels

An enzyme that converts the dietary carotenoid beta carotene into vitamin A in the body may also regulate testosterone levels and growth of the prostate, a new study found.

7 Dec 2016

New research reveals role of two genetic mutations in subset of acute myeloid leukemia

Two genetic mutations known to play a role in many solid cancers might also help explain why a subset of acute myeloid leukemia (AML) patients develop the disease, according to new research from The Ohio State University Comprehensive Cancer Center - Arthur G. James Cancer Hospital and Richard J. Solove Research Institute.

7 Dec 2016

Researchers create 2-for-1 vaccine that protects mice from MERS and rabies

In a new study, researchers have modified a rabies virus, so that it has a protein from the MERS virus; this altered virus works as a 2-for-1 vaccine that protects mice against both Middle East Respiratory Syndrome (MERS) and rabies.

7 Dec 2016

New study suggests how risk gene linked to ADHD may work

Genetics play a strong part in the development of attention-deficit/hyperactivity disorder (ADHD), but the path from a gene to risk for the disorder has remained a black box to researchers.

7 Dec 2016

Detecting inflammation in diabetic patients

As well as presenting with high blood glucose, diabetic patients have chronic low-grade inflammation, which can be measured by a range of inflammatory markers such as so-called high-sensitive CRP, TNFa and IL-6 as well as a full blood cell count.

7 Dec 2016

Researchers identify critical paralog groups with indispensable role in cellular signalling pathways

Throughout evolutionary history, there have been genetic elements that have duplicated - giving rise to genes with different functions.

7 Dec 2016

Researchers to study effect of watermelon juice in reducing heart disease

University of Alabama researchers soon will launch a study that looks at watermelon juice as a way to reduce heart disease.

6 Dec 2016

UCLA researchers discover how chronic inflammation increases prostate cancer risk

UCLA researchers have discovered a previously unrecognized type of progenitor cell that, though rare in most regions of the human prostate, is found in uncommonly high numbers in inflamed areas of the gland.

6 Dec 2016

Scientists uncover changes in immediate environment of DNA after fertilization

A team of scientists at the Helmholtz Zentrum München shows changes in the immediate environment of DNA after the ovum and sperm fuse to form the zygote. The results suggest why all conceivable somatic cells can develop from the germ cells. The study has been published in the journal 'Genes and Development'.

6 Dec 2016

Scientists discover new biomarker to help determine aggressiveness of brain cancer

Researchers at UT Southwestern Medical Center have found a new biomarker for glioma, a common type of brain cancer, that can help doctors determine how aggressive a cancer is and that could eventually help determine the best course of treatment.

6 Dec 2016

Small fat-burning molecule could help combat global epidemic of obesity

A small molecule could provide valuable help in combating the global epidemic of obesity.

6 Dec 2016

Research findings point to inherited genetic basis of ALL risk in children

A late-breaking abstract being presented today during the 58th American Society of Hematology Annual Meeting and Exposition in San Diego identifies inherited genetic mutations in the gene IKZF1 that confer a higher likelihood of developing pediatric acute lymphocytic leukemia (ALL).

6 Dec 2016

Experts discuss ways to integrate whole genome analysis into clinical practice at Congenica webinar

Whole genome analysis – where all of a patient’s genes are screened for potential disease causing variants – offers the potential for a rapid, responsive NHS testing service.

6 Dec 2016

Genetic News and Research

Pioneering research in caves provides new insights into origins of antibiotic resistance

New mathematical model suggests how AD may progress to become chronic

Researchers developing model to predict breast cancer patient’s response to chemotherapy

Researchers discover biological pathway that plays vital role in tumor development

Older women with metastatic breast cancer more likely to have genetic alterations in tumors

Pathogenic variants in certain genes increase woman's likelihood of developing breast cancer

Cold Spring Harbor Laboratory Press publishes new book on key aspects of ciliary biology

Enzyme that cleaves beta carotene may control testosterone levels

New research reveals role of two genetic mutations in subset of acute myeloid leukemia

Researchers create 2-for-1 vaccine that protects mice from MERS and rabies

New study suggests how risk gene linked to ADHD may work

Detecting inflammation in diabetic patients

Researchers identify critical paralog groups with indispensable role in cellular signalling pathways

Researchers to study effect of watermelon juice in reducing heart disease

UCLA researchers discover how chronic inflammation increases prostate cancer risk

Scientists uncover changes in immediate environment of DNA after fertilization

Scientists discover new biomarker to help determine aggressiveness of brain cancer

Small fat-burning molecule could help combat global epidemic of obesity

Research findings point to inherited genetic basis of ALL risk in children

Experts discuss ways to integrate whole genome analysis into clinical practice at Congenica webinar

Sequencing & Genomics: Elevating Science and Healthcare eBook

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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