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Experimental T-cell therapy shows promise in preventing AML relapse

Fred Hutchinson Cancer Research Center announced promising results from an early trial in which patients with high-risk acute myeloid leukemia received genetically engineered immune cells.

6 Dec 2016

Tufts scientists discover reason for incidence of genetic error that causes many disorders

Tufts University researchers have discovered a possible explanation for the occurrence of a genetic error that causes over a dozen neuromuscular and neurodegenerative disorders, including Huntington's disease, myotonic dystrophy and forms of spinocerebellar ataxia.

6 Dec 2016

Brains of people with autism share similar pattern of abnormal gene activity, UCLA study shows

Autism spectrum disorder is caused by a variety of factors, both genetic and environmental.

5 Dec 2016

Simple, coordinated approach can improve chances of survival for high-risk AML patients

New research shows that quickly identifying patients with high-risk acute myeloid leukemia (AML), and speeding the process to find them a stem cell donor and performing the transplant earlier, can significantly improve their chances of surviving for at least two years after diagnosis without a relapse.

5 Dec 2016

Starvation may shorten lifespans of children and male descendants, study suggests

New Tel Aviv University research suggests that periods of fasting or starvation may significantly shorten the lifespans of both children and their male descendants.

5 Dec 2016

MUSC researchers harness cutting-edge technology to uncover new role for pericytes during stroke

Pericytes are the primary locus of matrix-mellaproteinase-9-dependent (MMP-9) capillary damage and blood leakage during ischemia, according to preclinical findings reported by Medical University of South Carolina investigators in an article published online on November 14, 2016 by The Journal of Neuroscience.

5 Dec 2016

New drug treatment can override genetic fault that causes choroideremia

Researchers with funding from Fight for Sight have demonstrated that a new drug treatment for cystic fibrosis and Duchenne muscular dystrophy can override a genetic fault that causes choroideremia – a severe blinding disorder.

5 Dec 2016

Hemophilia B patients produce near-normal levels of clotting factor IX after gene therapy, study shows

Researchers are reporting the highest and most sustained levels to date of the essential blood-clotting factor IX in patients with the inherited bleeding disorder hemophilia B.

4 Dec 2016

Clonal hematopoiesis may help predict cancer patients at risk for fatal form of leukemia

Patients successfully treated for breast, colon and other cancers can go on to develop an often-fatal form of leukemia, sometimes years after completion of treatment, due to a genetic mutation leading to secondary malignancies known as therapy-related myeloid neoplasms (t-MNs).

4 Dec 2016

Genetic differences between brain cancer cells and normal tissues could offer clues to tumor behavior

Two recently discovered genetic differences between brain cancer cells and normal tissue cells -- an altered gene and a snippet of noncoding genetic material -- could offer clues to tumor behavior and potential new targets for therapy, Johns Hopkins scientists report.

2 Dec 2016

Combination of demineralized bone and gene therapy shows promise for treating pseudarthrosis

A team headed by Professor Albert Rizvanov, director of the Gene and Cell Technologies Open Lab, created a gene therapy drug that encodes growth factors for the stimulation of blood vessel and bone formation.

2 Dec 2016

Newcastle scientists develop promising new test to identify patients with rare liver disease

Newcastle scientists and medics have developed a promising new test to identify patients with a rare liver disease who will not respond to standard treatment, allowing earlier intervention with alternatives.

2 Dec 2016

Researchers receive Stafford Fox Medical Research Foundation grant to accelerate CFS diagnosis

Major improvement in the diagnosis of Chronic Fatigue Syndrome is expected following the award of $4m in funding to one of Australia’s foremost authorities on the condition.

2 Dec 2016

Elucigene collaborates with Congenica to develop new NGS kit for cystic fibrosis

The emergence of new therapies that treat the causes of cystic fibrosis are creating an imperative for more accurate variant analysis.

2 Dec 2016

Reseachers identify cellular ‘off’ switch for inflammatory immune response in asthma attacks

Working with human immune cells in the laboratory, Johns Hopkins researchers report they have identified a critical cellular "off" switch for the inflammatory immune response that contributes to lung-constricting asthma attacks.

2 Dec 2016

Cigarette smoking may lead to fibrosis in the heart and kidneys, study reveals

Smoking may lead to fibrosis in the heart and kidneys and can worsen existing kidney disease, according to a new study.

1 Dec 2016

Scientists discover molecular link between rare childhood genetic disease and major cancer gene

A team of researchers led by a University of Rhode Island scientist has discovered an important molecular link between a rare childhood genetic disease, Fanconi anemia, and a major cancer gene called PTEN.

1 Dec 2016

Protective barrier inside chromosomes helps prevent errors during cell division, study finds

Fresh insights into the structures that contain our genetic material could explain how the body's cells stay healthy.

1 Dec 2016

New study finds genetic link between Parkinson's disease and cognitive decline

Although the hallmark symptoms of Parkinson's disease (PD) - such as involuntary shaking, slowness of movement and muscle rigidity - are related to movement, recent evidence has suggested that memory impairment plays an outsized role in diminished quality of life and the burden placed on caregivers.

1 Dec 2016

Bone density could be one of early indicators of brain degeneration in Alzheimer's disease

Researchers at NEOMED have just identified a major connection between areas of the brainstem - the ancient area that controls mood, sleep and metabolism - and detrimental changes to bone in a preclinical model of Alzheimer's disease (AD).

1 Dec 2016

Genetic News and Research

Experimental T-cell therapy shows promise in preventing AML relapse

Tufts scientists discover reason for incidence of genetic error that causes many disorders

Brains of people with autism share similar pattern of abnormal gene activity, UCLA study shows

Simple, coordinated approach can improve chances of survival for high-risk AML patients

Starvation may shorten lifespans of children and male descendants, study suggests

MUSC researchers harness cutting-edge technology to uncover new role for pericytes during stroke

New drug treatment can override genetic fault that causes choroideremia

Hemophilia B patients produce near-normal levels of clotting factor IX after gene therapy, study shows

Clonal hematopoiesis may help predict cancer patients at risk for fatal form of leukemia

Genetic differences between brain cancer cells and normal tissues could offer clues to tumor behavior

Combination of demineralized bone and gene therapy shows promise for treating pseudarthrosis

Newcastle scientists develop promising new test to identify patients with rare liver disease

Researchers receive Stafford Fox Medical Research Foundation grant to accelerate CFS diagnosis

Elucigene collaborates with Congenica to develop new NGS kit for cystic fibrosis

Reseachers identify cellular ‘off’ switch for inflammatory immune response in asthma attacks

Cigarette smoking may lead to fibrosis in the heart and kidneys, study reveals

Scientists discover molecular link between rare childhood genetic disease and major cancer gene

Protective barrier inside chromosomes helps prevent errors during cell division, study finds

New study finds genetic link between Parkinson's disease and cognitive decline

Bone density could be one of early indicators of brain degeneration in Alzheimer's disease

eBook: Using iPSCs models for human disease research and drug discovery eBook

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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