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$Study finds no link between PPI use and bone fractures in patients with Barrett's esophagus$

Study finds no link between PPI use and bone fractures in patients with Barrett's esophagus

Proton pump inhibitors (PPIs)—medications commonly used to treat heartburn, acid reflux, and ulcers—have been linked with potentially serious side effects including a possible increased risk of bone fractures.

9 Oct 2017

New U-M study examines why overtreatment in older breast cancer patients persists

Recent clinical trials have shown that 90 percent of early stage breast cancer patients over age 70 do not benefit from radiation after breast-conserving surgery. And yet, use of radiation in this context has dropped only minimally.

9 Oct 2017

New studies provide insight into treatments for Barrett's esophagus

The October issue of GIE: Gastrointestinal Endoscopy features several new studies evaluating various treatments for Barrett's esophagus (BE). Two of these studies are highlighted below. BE is a condition in which there are unusual changes to the cells lining the esophagus. It is believed to be most commonly due to inflammation from gastroesophageal reflux disease (GERD).

6 Oct 2017

New microcapsules represent promising vectors for application of genome-editing tools

Researchers from Tomsk Polytechnic University jointly with their colleagues from St. Petersburg, Hamburg and London have conducted a study in the course of which it was found out that polymer and hybrid silica-coated microcapsules are more efficient in genome-editing when applying CRISPR-Cas9 system.

6 Oct 2017

Genetic signature within prostate cancer cells can predict metastatic tumors

Many prostate cancers, which generally are diagnosed in older men, are "indolent," slow-growing tumors that aren't destined to be fatal. But some tumors are prone to becoming aggressive and spreading beyond the prostate, making them difficult to treat and life-threatening.

6 Oct 2017

Research explains why mTOR inhibitors show limited ability to kill cancer

Anti-cancer drugs called mTOR inhibitors slow the growth of cancer cells but show limited ability to cause cancer cell death. New studies explain why.

6 Oct 2017

World’s smallest pacemaker for cardiology patients now offered at Medical City Dallas

Medical City Dallas is now offering the world’s smallest pacemaker for cardiology patients. The Micra pacemaker is a new type of heart device that provides patients with the most advanced pacing technology at one-tenth the size of a traditional pacemaker.

6 Oct 2017

CGT Catapult’s iPSC line licensed to Universal Cells for creating universal donor cell line

The Cell and Gene Therapy Catapult today announced a non-exclusive licensing agreement to provide its clinical-grade induced Pluripotent Stem Cell line to Seattle based Universal Cells.

6 Oct 2017

New cell therapy restores movement in people with paralyzing spinal cord injuries

Four of six people with paralyzing spinal cord injuries who were treated with a new cell therapy have recovered two or more motor levels on at least one side, new study results show.

6 Oct 2017

Transitioning to automated liquid handling

We are working in the field of biomedical engineering and our specific focus is on the development of biohybrid medical systems or biohybrid implants.

From Beckman Coulter Life Sciences - Automation and Genomics 6 Oct 2017

NIH awards $2.3 million grant to Umass Amherst microbiologist for TB research

The National Institutes of Health announced today that microbiologist Sloan Siegrist at the University of Massachusetts Amherst has received a five-year, $2.3 million National Institutes of Health New Innovator Award, which supports "unusually innovative research from early career investigators," to study the bacterium that causes tuberculosis (TB).

5 Oct 2017

Monoclonal antibody “cocktail” inhibits Zika infection, study reveals

A collaborative study conducted by the Miller School of Medicine, University of Miami has revealed that a monoclonal antibody “cocktail” inhibited zika virus (ZIKV) infection in primates.

5 Oct 2017

New spray drying technique helps reduce concentration of active ingredients in therapeutic drugs

Instant coffee and powdered milk are produced by spray drying. Fraunhofer researchers have adapted this technique to the tricky question of incorporating insoluble substances in core-shell particles. The new method helps reduce the concentration of active ingredients in therapeutic medications.

5 Oct 2017

Scientists develop synthetic molecule effective at kicking and killing HIV

Current anti-AIDS drugs are highly effective at making HIV undetectable and allowing people with the virus to live longer, healthier lives. The treatments, a class of medications called antiretroviral therapy, also greatly reduce the chance of transmission from person to person.

5 Oct 2017

Moms of children with rare genetic illness push for wider newborn screening

Kerri De Nies received the news this spring from her son's pediatrician: Her chubby-cheeked toddler had a rare brain disorder.

5 Oct 2017

Study finds underutilization of sperm banking by at-risk patients with cancer

A comprehensive study of adolescent and young adult cancer patients found just 43.8 percent of those at risk for infertility banked sperm prior to cancer therapy, suggesting that patients might benefit from efforts to increase awareness and understanding of the option.

5 Oct 2017

Gene therapy effectively stabilizes progression of cerebral adrenoleukodystrophy, trial reveals

In a recent clinical trial, a gene therapy to treat cerebral adrenoleukodystrophy (CALD) -- a neurodegenerative disease that typically claims young boys' lives within 10 years of diagnosis -- effectively stabilized the disease's progression in 88 percent of patients, researchers from the Dana-Farber/Boston Children's Cancer and Blood Disorders Center and Massachusetts General Hospital report today.

4 Oct 2017

Study on cell stress response may hold promise for treating inflammation-related disorders

Stress – defined broadly – can have a profoundly deleterious effect on the human body. Even individual cells have their own way of dealing with environmental strains such as ultraviolet radiation from the sun or germs.

4 Oct 2017

Gene targets for triple negative breast cancers resistant to chemotherapy found

Researchers have finally found the genetic targets that could be used for treatment and development of new drugs in patients who are resistant to chemotherapy. These patients who are resistant to chemotherapy are most likely to have triple negative breast cancer which is the most aggressive form of breast cancer. The study appeared in the latest issue of the journal Cell Metabolism.

4 Oct 2017

Tattoo ink from 15 years ago mimics lymph node cancer: Case study

A 30 year old Australian woman presented to the doctors with numerous small lumps under her arms for around two weeks. When one of the nodes were put under the microscope, the doctors found pigments from tattoo ink that she’d got 15 years back.

4 Oct 2017

Therapy News and Research

Study finds no link between PPI use and bone fractures in patients with Barrett's esophagus

New U-M study examines why overtreatment in older breast cancer patients persists

New studies provide insight into treatments for Barrett's esophagus

New microcapsules represent promising vectors for application of genome-editing tools

Genetic signature within prostate cancer cells can predict metastatic tumors

Research explains why mTOR inhibitors show limited ability to kill cancer

World’s smallest pacemaker for cardiology patients now offered at Medical City Dallas

CGT Catapult’s iPSC line licensed to Universal Cells for creating universal donor cell line

New cell therapy restores movement in people with paralyzing spinal cord injuries

Transitioning to automated liquid handling

NIH awards $2.3 million grant to Umass Amherst microbiologist for TB research

Monoclonal antibody “cocktail” inhibits Zika infection, study reveals

New spray drying technique helps reduce concentration of active ingredients in therapeutic drugs

Scientists develop synthetic molecule effective at kicking and killing HIV

Moms of children with rare genetic illness push for wider newborn screening

Study finds underutilization of sperm banking by at-risk patients with cancer

Gene therapy effectively stabilizes progression of cerebral adrenoleukodystrophy, trial reveals

Study on cell stress response may hold promise for treating inflammation-related disorders

Gene targets for triple negative breast cancers resistant to chemotherapy found

Tattoo ink from 15 years ago mimics lymph node cancer: Case study

Advancing Neuroscience Research Through Collaboration and Patient-Centered Innovation

The impact of vibration on microscopy

How Omics Technologies Are Transforming Biological Research and Drug Discovery

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