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Editing preferences of enzymes may play role in infertility and cancer

To "turn off" particular regions of genes or protect them from damage, DNA strands can wrap around small proteins, called histones, keeping out all but the most specialized molecular machinery.

28 Nov 2016

Gene mutation appears to increase risk of Parkinson's disease in Caucasians

A defect in a gene that produces dopamine in the brain appears to accelerate the onset of Parkinson's disease, according to new research from Iowa State University. The effect is particularly dramatic for people under age 50.

28 Nov 2016

New study finds link between memory mechanisms and resistance to epilepsy

A new study undertaken jointly by researchers from the Sagol Department of Neurobiology at the University of Haifa and European researchers, published in the journal Cerebral Cortex, exposes a new biological mechanism that, on the one hand, damages a very specific type of memory, but at the same time provides resistance to epilepsy.

25 Nov 2016

ASGCT seeks to educate public and policy-makers on fundamentals of gene editing

On Nov. 21, 2016, the American Society of Gene & Cell Therapy released Therapeutic Gene Editing: an ASGCT White Paper, intended to provide policy-makers, patient advocates, and the interested public with the necessary background information in anticipation of an upcoming consensus report on human gene editing from the National Academy of Sciences and National Academy of Medicine (NAS), expected to be released in early 2017.

24 Nov 2016

Study shows essential role of new receptor in protecting against obesity

The team of scientists from King's College London and Imperial College London tested a high-fat diet, containing a fermentable carbohydrate, and a control diet on mice and looked at the effect on food intake of those with and without the FFAR2 receptor.

24 Nov 2016

VIB researchers develop new tool to diagnose Familial Mediterranean Fever

Researchers at VIB and Ghent University have developed a tool to diagnose Familial Mediterranean Fever (FMF).

24 Nov 2016

New ULB study shows how cancer cell of origin controls malignant transition

Researchers at the Université libre de Bruxelles, ULB define for the first time how the cancer cell of origin controls invasive and metastatic properties of tumor cells.

24 Nov 2016

Vitamin D supplements do not prevent disease in the majority, says study

Current evidence does not support that vitamin D supplementation does anything to help prevent disease among the majority of people, according to a new study published in the British Medical Journal (BMJ).

24 Nov 2016

Researchers engineer cells with 'built-in genetic circuit' that can inhibit tumour growth

Researchers at the University of Southampton have engineered cells with a 'built-in genetic circuit' that produces a molecule that inhibits the ability of tumours to survive and grow in their low oxygen environment.

24 Nov 2016

Cancer gene mutations can predict response to less intensive treatment in AML patients

Patients with the most lethal form of acute myeloid leukemia (AML) - based on genetic profiles of their cancers - typically survive for only four to six months after diagnosis, even with aggressive chemotherapy.

23 Nov 2016

HSCI researchers use color tagging system to track development of blood stem cells

Harvard Stem Cell Institute (HSCI) researchers have used a colorful, cell-labeling technique to track the development of the blood system and trace the lineage of adult blood cells travelling through the vast networks of veins, arteries, and capillaries back to their parent stem cell in the marrow.

23 Nov 2016

Researchers identify simple, inexpensive tool for assessing prognosis of pediatric brain tumors

A multi-institutional group of researchers, led by investigators at Children's Hospital Los Angeles and the University of Michigan, have identified a simple and inexpensive tool for assessing the prognosis of pediatric brain tumors called ependymomas.

23 Nov 2016

Scientists develop new technology that sheds light on HIV infection

A group of researchers at the Centre for Genomic Regulation and the Pompeu Fabra University in Barcelona, Spain, have developed a new technology that sheds light on the HIV infection and offers a first glance at the expression landscape of the HIV in the human genome.

23 Nov 2016

Biologists create bright red fluorescent protein to track essential cellular processes

After years of trying, biologists have succeeded in creating an extremely bright red fluorescent protein in the lab.

23 Nov 2016

Study reveals link between genes for academic achievement and partner choices

A study co-led by the University of East Anglia (UEA) has found that people with genes for high educational achievement tend to marry, and have children with, people with similar DNA.

23 Nov 2016

Mayo Clinic researchers discover potential cause and new treatment for rare soft tissue cancer

Researchers at Mayo Clinic Center for Individualized Medicine have discovered a potential cause and a promising new treatment for inflammatory myofibroblastic tumors, a rare soft tissue cancer that does not respond to radiation or chemotherapy.

22 Nov 2016

Study shines new light on genetic makeup of river blindness parasite

The parasite that causes river blindness infects about 37 million people in parts of Africa and Latin America, causing blindness and other major eye and skin diseases in about 5 million of them.

22 Nov 2016

New color-coding tool sheds light on blood disorders, cancers by tracking clonal stem cells

A new color-coding tool is enabling scientists to better track live blood stem cells over time, a key part of understanding how blood disorders and cancers like leukemia arise, report researchers in Boston Children's Hospital's Stem Cell Research Program.

22 Nov 2016

Study finds genomic regions with copy number variants linked to schizophrenia risk

Many of the genetic variations that increase risk for schizophrenia are rare, making it difficult to study their role in the disease.

22 Nov 2016

Einstein researcher receives $7.5 million NIH grant to study genetics of congenital heart disease

The National Institutes of Health has awarded Bernice Morrow, Ph.D., at Albert Einstein College of Medicine and collaborators at the Children's Hospital of Philadelphia a five-year, $7.5 million grant to study the genetics of congenital heart abnormalities.

22 Nov 2016

Genetic News and Research

Editing preferences of enzymes may play role in infertility and cancer

Gene mutation appears to increase risk of Parkinson's disease in Caucasians

New study finds link between memory mechanisms and resistance to epilepsy

ASGCT seeks to educate public and policy-makers on fundamentals of gene editing

Study shows essential role of new receptor in protecting against obesity

VIB researchers develop new tool to diagnose Familial Mediterranean Fever

New ULB study shows how cancer cell of origin controls malignant transition

Vitamin D supplements do not prevent disease in the majority, says study

Researchers engineer cells with 'built-in genetic circuit' that can inhibit tumour growth

Cancer gene mutations can predict response to less intensive treatment in AML patients

HSCI researchers use color tagging system to track development of blood stem cells

Researchers identify simple, inexpensive tool for assessing prognosis of pediatric brain tumors

Scientists develop new technology that sheds light on HIV infection

Biologists create bright red fluorescent protein to track essential cellular processes

Study reveals link between genes for academic achievement and partner choices

Mayo Clinic researchers discover potential cause and new treatment for rare soft tissue cancer

Study shines new light on genetic makeup of river blindness parasite

New color-coding tool sheds light on blood disorders, cancers by tracking clonal stem cells

Study finds genomic regions with copy number variants linked to schizophrenia risk

Einstein researcher receives $7.5 million NIH grant to study genetics of congenital heart disease

eBook: Using iPSCs models for human disease research and drug discovery eBook

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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