Protein C News and Research

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Alzheimer's could possibly be spread via contaminated neurosurgery

Researchers have found that surgical instruments used for neurosurgery could get contaminated by the altered brain proteins that are seen in Alzheimer’s disease. These instruments are capable of spreading the condition if not treated or decontaminated properly before reuse. The study results were published in the latest issue of the journal Nature.

14 Dec 2018

Recent developments and challenges in hMAT inhibitors

Zhu et al. have reviewed the recent developments in the knowledge about the binding, inhibitory mechanisms and structure-activity relationships of hSERT, hNET and hDAT, which are primary human monoamine transporters hMATs.

14 Dec 2018

Researchers discover protein involved in nematode stress response

When humans experience stress, their inner turmoil may not be apparent to an outside observer. But many animals deal with stressful circumstances - overcrowded conditions, not enough food - by completely remodeling their bodies.

14 Dec 2018

Study provides new insights into molecular mechanisms underlying role of amyloid in Alzheimer's disease

A UCL-led study has confirmed that some vials of a hormone used in discontinued medical treatments contained seeds of a protein implicated in Alzheimer's disease, and are able to seed amyloid pathology in mice.s

14 Dec 2018

Study finds drug targets for Ebola, Dengue, and Zika viruses

No drugs are currently available to treat Ebola, Dengue, or Zika viruses, which infect millions of people every year and result in severe illness, birth defects, and even death. New research from the Gladstone Institutes and UC San Francisco may finally change that. Scientists identified key ways the three viruses hijack the body's cells, and they found at least one potential drug that can disrupt this process in human cells.

13 Dec 2018

Study uncovers new genetic clues to frontotemporal dementia

Unlike the more common Alzheimer's disease, frontotemporal dementia tends to afflict young people. It accounts for an estimated 20 percent of all cases of early-onset dementia.

13 Dec 2018

Researchers discover Ebola-fighting protein in human cells

Researchers have discovered a human protein that helps fight the Ebola virus and could one day lead to an effective therapy against the deadly disease, according to a new Northwestern Medicine study.

13 Dec 2018

New project aims to understand why and how metabolic disorders develop in patients

The global prevalence of diabetes has reached more than 410 million individuals, underscoring the need for novel therapeutic strategies targeting the pathology as a multi-organ disease.

13 Dec 2018

Study: Loss of tight junction barrier protein results in gastric cancer development

Tight junctions are multi-protein complexes that serve as barriers in epithelial tissues such as the skin or lining of the gut. Loss of a specific tight junction barrier protein, claudin 18, occurs in the majority of gastric cancer patients and is correlated with poor prognosis in patients with advanced gastric cancer.

13 Dec 2018

New method to visualize small-molecule interactions inside cells

Like people in a large company, proteins in cells constantly interact with each other to perform various jobs. To develop new disease therapies, researchers are trying to control these interactions with small-molecule drugs that cause specific proteins to associate more or less with their "coworkers."

13 Dec 2018

Recent findings on rare genetic disorder may help develop new treatment options

Fresh discoveries about a rare genetic disorder that affects mainly boys may inform the development of therapies to treat the condition.

13 Dec 2018

New mouse model shows potential for rapid identification of promising muscular dystrophy therapies

A Massachusetts General Hospital research team has created a new mouse model of a common form of muscular dystrophy with the potential of rapidly distinguishing promising therapeutic drugs from those unlikely to be successful.

13 Dec 2018

Unraveling the complexity of cancer biology can prompt new avenues for drug development

Unraveling the complexity of cancer biology can lead to the identification of new molecules involved in breast cancer and prompt new avenues for drug development. And proteogenomics, an integrated, multipronged approach, seems to be a way to do it.

13 Dec 2018

New substance could improve efficacy of established breast cancer treatments

Physicians from Karl Landsteiner University of Health Sciences in Krems (Austria) demonstrate potential for clinical application, collaborating with research groups from Germany, the USA, and China.

13 Dec 2018

Research identifies new therapeutic target for cancer treatment and tissue regeneration

Research led by the University of Plymouth and Technische Universität Dresden has identified a new therapeutic target for cancer treatment and tissue regeneration - a protein called Prominin-1.

13 Dec 2018

New protein complex helps embryonic stem cells to maintain their indefinite potential

Embryonic stem cells (ESCs) are the very definition of being full of potential, given that they can become any type of cell in the body. Once they start down any particular path toward a type of tissue, they lose their unlimited potential.

12 Dec 2018

Researchers develop new method to produce natural sweetener

A research group from Oulu University has developed a method capable of producing the natural sweetener brazzein. Production of brazzein as a good tasting sweetener has long been in development but until now, no solution for commercial production has been found.

12 Dec 2018

Nobel Laureates lecture about immune checkpoint therapy for cancer treatment

The Nobel Lectures held by the laureates of the 2018 Nobel Prize in Physiology or Medicine saw Aula Medica at Karolinska Institutet filled to the brink. In addition to 1,000 audience members in the auditorium, people around the world were able to watch the live broadcast when James P. Allison and Tasuku Honjo talked about their research, the results of which have led to the ground-breaking immune checkpoint therapy for cancer treatment.

12 Dec 2018

IONTAS founder and pioneer in phage display technology attends Nobel Prize Award Ceremony

Dr. John McCafferty celebrates the success of phage display technology with Nobel Prize in Chemistry Laureates.

From FairJourney Biologics 12 Dec 2018

Study reveals role of brain mechanism in memory recall

Whether it's the pleasant experience of returning to one's childhood home over the holidays or the unease of revisiting a site that proved unpleasant, we often find that when we return to a context where an episode first happened, specific and vivid memories can come flooding back.

12 Dec 2018

Protein C News and Research

Alzheimer's could possibly be spread via contaminated neurosurgery

Recent developments and challenges in hMAT inhibitors

Researchers discover protein involved in nematode stress response

Study provides new insights into molecular mechanisms underlying role of amyloid in Alzheimer's disease

Study finds drug targets for Ebola, Dengue, and Zika viruses

Study uncovers new genetic clues to frontotemporal dementia

Researchers discover Ebola-fighting protein in human cells

New project aims to understand why and how metabolic disorders develop in patients

Study: Loss of tight junction barrier protein results in gastric cancer development

New method to visualize small-molecule interactions inside cells

Recent findings on rare genetic disorder may help develop new treatment options

New mouse model shows potential for rapid identification of promising muscular dystrophy therapies

Unraveling the complexity of cancer biology can prompt new avenues for drug development

New substance could improve efficacy of established breast cancer treatments

Research identifies new therapeutic target for cancer treatment and tissue regeneration

New protein complex helps embryonic stem cells to maintain their indefinite potential

Researchers develop new method to produce natural sweetener

Nobel Laureates lecture about immune checkpoint therapy for cancer treatment

IONTAS founder and pioneer in phage display technology attends Nobel Prize Award Ceremony

Study reveals role of brain mechanism in memory recall

Industry Focus eBook - Neurology/Neuroscience - 2nd edition eBook

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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