Atherosclerosis News and Research

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Atherosclerosis is the progressive buildup of plaque - the fatty deposits and other cells - in the inner walls of the arteries. The condition is a consequence of elevated cholesterol and for many it's a silent disease, with no visible signs or symptoms. The disease can begin in early adulthood and continues to progress for the rest of a person's life. Despite the serious nature of atherosclerosis, many people do not understand how it develops and progresses.

Gut microbiome pattern predicts future heart attack risk in coronary heart disease patients

A specific gut microbiota pattern was found to predict new cardiovascular events in patients with coronary heart disease, based on data from the CORDIOPREV study. Researchers developed a microbiota-based risk score that may improve secondary prevention.

21 Apr 2025

New scoring system predicts stroke risk and reduces need for surgery

Researchers at UCL have tested a new scoring system to measure the risk of stroke in patients with narrowed arteries due to atherosclerosis, which could prevent unnecessary surgeries and stents.

16 Apr 2025

Study reveals a potential breakthrough in treating osteonecrosis of the femoral head

A recent study has uncovered a potential breakthrough in treating osteonecrosis of the femoral head (ONFH), a debilitating bone disease that causes severe pain and joint collapse.

15 Apr 2025

Study finds connection between hearing impairment and heart failure risk

Hearing loss is linked to a heightened risk of developing heart failure, with the psychological distress caused by the impairment taking a key role in the observed association, finds a large long term study, published online in the journal Heart.

9 Apr 2025

Swedish researchers identify genetic variants linked to atherosclerosis

Swedish researchers have identified genetic variants that increase the risk of atherosclerosis. The aim is for these new findings to enable earlier detection of atherosclerosis and improved treatment of cardiovascular diseases such as heart attack and stroke.

31 Mar 2025

This molecule links your diet to stroke and Alzheimer’s—here’s how to stop it

A new review explores how TMAO, a gut-derived metabolite from red meat and other foods, contributes to heart and brain diseases. It also highlights promising interventions—like plant-based diets, probiotics, and nutraceuticals—to lower TMAO levels and reduce health risks.

26 Mar 2025

Study shows red wine biomarkers in urine can predict inflammation levels

Researchers found that specific metabolites of resveratrol in urine accurately reflect red wine consumption. These biomarkers were linked to reduced inflammation in older adults at cardiovascular risk, unlike traditional food surveys.

25 Mar 2025

Understanding the role of iron-dependent ferroptosis in immune suppression

Iron-dependent ferroptosis, a non-apoptotic cell death mechanism, is gaining attention for its role in immune suppression.

24 Mar 2025

Duke-NUS and NUS Medicine launch first-ever joint center to drive metabolomics research

In a strategic move for medical research and innovation, Duke-NUS Medical School and the National University of Singapore Yong Loo Lin School of Medicine (NUS Medicine) have launched the Systems Metabolomics Centre (SysMeC), their first-ever joint research center.

22 Mar 2025

Smartwatch data could offer new way to assess cardiovascular health

The answer to your heart health may be on your wrist, a new study suggests. Researchers have developed a new way to assess cardiovascular health based on information routinely collected by smartwatches, according to a study being presented at the American College of Cardiology's Annual Scientific Session (ACC.25).

20 Mar 2025

Colorectal cancer patients face increased risk of cardiovascular death

People diagnosed with colorectal cancer are significantly more likely to die of cardiovascular causes than the general population, especially in the first two years after their cancer diagnosis and in people younger than 50, according to a study being presented at the American College of Cardiology's Annual Scientific Session (ACC.25).

20 Mar 2025

Polluted soil and water are fueling a global heart disease epidemic

A new study in Atherosclerosis shows that soil and water pollution, including microplastics and toxic chemicals, significantly raise cardiovascular disease risks. The research highlights how emerging contaminants and poor environmental practices drive global health threats.

16 Mar 2025

Social advantage reduces risk of age-related diseases and slows aging

People with favorable socioeconomic conditions, such as high incomes or education levels, face a reduced risk of age-related diseases and show fewer signs of biological aging than peers of the same age, finds a new study led by University College London (UCL) researchers.

14 Mar 2025

How gut health shapes heart disease risk — and what you can do about it

A new review highlights how gut microbiome imbalances contribute to cardiovascular disease by altering short-chain fatty acids, TMAO, and inflammatory pathways. The study emphasizes the potential of prebiotics, probiotics, and dietary changes to restore gut health and reduce heart disease risk.

13 Mar 2025

Limiting TV time may reduce heart disease risk for people with genetic risk for diabetes

Watching no more than one hour of TV a day may lower the risk of heart attack, stroke and other blood vessel diseases among people with varying levels of genetic risk for Type 2 diabetes, including high genetic risk, according to new research published today in the Journal of the American Heart Association, an open access, peer-reviewed journal of the American Heart Association.

12 Mar 2025

Long-term NSAID use may lower dementia risk

Long-term NSAID use reduces dementia risk, particularly in those without the APOE-ε4 gene, highlighting the importance of sustained anti-inflammatory treatment over dosage levels.

9 Mar 2025

Intermittent fasting cuts heart attack risk by preventing dangerous blood clots

Intermittent fasting may reduce the risk of blood clots and cardiovascular disease by inhibiting platelet activation.

2 Mar 2025

Exploring the role of SNPs in early diagnosis of coronary microvascular dysfunction

A new review highlights the potential role of single nucleotide polymorphisms (SNPs) in improving the early diagnosis and targeted intervention of coronary microvascular dysfunction (CMD)—a condition linked to myocardial ischemia despite the absence of major artery blockages.

26 Feb 2025

Researchers discover key signaling pathway involved in atherosclerotic plaques

CD8+ T cells accumulate in atherosclerotic plaques. LMU researchers identify a crucial signaling pathway - with therapeutic potential.

25 Feb 2025

Antioxidant-enzyme interactions and their role in non-communicable diseases

Oxidative stress, caused by an imbalance between reactive oxygen species (ROS) and antioxidant defenses, plays a central role in the development of non-communicable diseases (NCDs).

21 Feb 2025