Bird Flu News and Research

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Orally effective FluCide anti-influenza drug candidate

NanoViricides, Inc. announced today that an anti-influenza drug candidate under its FluCide program is effective when given orally. The Company has received information that a FluCide drug candidate designed for oral administration has shown very strong efficacy in corresponding animal studies.

13 Aug 2012

New study maps global zoonotic disease 'hotspots'

"A global study mapping human diseases that come from animals like tuberculosis, AIDS, bird flu or Rift Valley fever has found that just 13 such diseases are responsible for 2.4 billion cases of human illness and 2.2 million deaths a year," Reuters reports.

6 Jul 2012

Study: 13 zoonoses responsible for 2.4B cases of human illness per year

A new global study mapping human-animal diseases like tuberculosis (TB) and Rift Valley fever finds that an "unlucky" 13 zoonoses are responsible for 2.4 billion cases of human illness and 2.2 million deaths per year. The vast majority occur in low- and middle-income countries.

5 Jul 2012

More sophisticated process needed to vet research for possible security threats

Noting that the journal Science last week published the second of two controversial bird flu research papers, in which a team led by Ron Fouchier of the Erasmus Medical Center in Rotterdam created a mutated strain of the virus that spreads easily among ferrets, a Washington Post editorial writes that "this is not the end of the story. Rather, it marks the beginning of an important chapter for both science and security."

29 Jun 2012

Congressman 'dissatisfied' with handling of controversial H5N1 papers calls for cohesive policy for handling 'risky' research

"Dissatisfied with the government's handling of two research papers on mutant forms of avian influenza," Rep. Jim Sensenbrenner (R-Wisc.) on Wednesday "said that the lack of a cohesive policy for handling risky research funded by the National Institutes of Health (NIH) and other federal agencies could necessitate new laws, a situation that researchers have been trying to avoid," the Nature News Blog reports.

29 Jun 2012

New York Times examines bird flu studies, history of controversy

The New York Times examines several studies published in the journals Nature and Science looking at how the H5N1 bird flu virus could mutate to become more virulent among humans and outlines the history of controversy surrounding the studies.

27 Jun 2012

Survey of home healthcare practices related to infection control

A healthy boy was infected with antibiotic-resistant bacterium that was traced to his mother's nurse's bag left in the family's car after his mother's home healthcare visit to a patient with the same infection. Although the boy's infection and the patient's infection were never DNA tested, the coincidence was remarkable.

26 Jun 2012

U.S. journal Science publishes controversial H5N1 research

The U.S. journal Science on Thursday published the results of a controversial study in which researchers at the Erasmus Medical Center in the Netherlands "identified five mutations apparently necessary to make the [H5N1] bird flu virus spread easily among ferrets, which catch the same flus that humans do," the New York Times reports (McNeil, 6/21).

22 Jun 2012

VaxInnate commences VAX161 Phase I trial in pandemic avian influenza

VaxInnate Corporation today announced that enrollment has commenced in a Phase I clinical trial to evaluate VAX161, its novel H5 vaccine candidate in development for the prevention of pandemic avian influenza or bird flu. VaxInnate is a biotechnology firm pioneering breakthrough technology for developing novel vaccines.

13 Jun 2012

Single test developed that detects all known strains of H5N1

The close collaboration between scientists from the Experimental Therapeutics Centre (ETC) under the Agency for Science and Technology Research (A*STAR) and clinicians from Tan Tock Seng Hospital (TTSH) has enabled the successful development of the most comprehensive and rapid H5N1 bird flu test kit available to date.

29 May 2012

Researchers barcode different strains of influenza virus and HRSV

Dr Julian Hiscox and Dr John Barr of the University's Faculty of Biological Sciences are working with the Health Protection Agency Porton (HPA) to build a bank of molecular signatures that will help identify the severity of virus infection from characteristic changes seen in cells. Currently the team is barcoding different strains of influenza virus and human respiratory syncytial virus (HRSV) - a virus associated with the onset of asthma in young children.

14 May 2012

Researchers discover potential way to develop universal flu vaccines

University of British Columbia researchers have found a potential way to develop universal flu vaccines and eliminate the need for seasonal flu vaccinations.

8 May 2012

NIH responds to criticism over handling of controversial bird flu studies

In a letter dated April 25, Amy Patterson, associate director for science policy in the office of the director of the National Institutes of Health, "has refuted criticism of the way a meeting held to allow a biosecurity advisory group to review controversial bird flu studies was handled," denying "the agenda was crafted to achieve a predetermined outcome," the Canadian Press/Winnipeg Free Press writes.

7 May 2012

Nature publishes first of two controversial studies on H5N1 avian flu

"In a long-awaited study that helped prompt a contentious debate over the wisdom of conducting research that has the potential to help as well as harm, scientists reported Wednesday that they had engineered a mutant strain of [H5N1] bird flu that can spread easily between ferrets -- a laboratory animal that responds to flu viruses much as people do," the Los Angeles Times (Brown, 5/3).

4 May 2012

One of the controversial avian flu studies published in full finally

After endless debates and controversies on whether two studies that demonstrated how bird flu, also known as avian H5N1 influenza, or avian flu, should be published, one of them has appeared in the latest issue of the journal Nature in its entirety. The two studies aimed for publication in journals Nature and Science show how the bird flu virus could become transmissible from mammal-to-mammal; as humans are mammals, the same would apply to humans.

4 May 2012

Flu paper publication amidst threats of bioterrorism raises need for better rules of censorship

According to the editor of the scientific journal Nature, Dr Philip Campbell current procedures to assess and censor medical research potentially of use to terrorists need to be improved. He was speaking about the recent controversy regarding the bird flu virus H5N1 study. The study was initially stopped from publication fearing risk of bioterrorism. He was speaking to BBC News.

2 May 2012

'Mandatory oversight' of potentially dangerous biological research will be necessary

"In the sobering annals of disaster prevention, genetic manipulation of the H5N1 influenza virus is looming as a seminal case," John Steinbruner, director of the Center for International Security Studies at the University of Maryland, writes in an opinion piece in The Hill's "Congress Blog," noting that two "laboratory experiments have rendered the highly virulent avian strain transmissible among ferrets, strongly suggesting that it would be transmissible among humans as well."

2 May 2012

Dutch government grants export license allowing publication of controversial H5N1 study

"The Dutch government has agreed to grant an export license to allow Ron Fouchier, a virologist at the Erasmus Medical University in Rotterdam, to publish his work on H5N1 avian influenza in Science," Nature's "News Blog" reports (Owens, 4/27). "

30 Apr 2012

Senate committee questions federal officials about dual-use research of concern procedures

"Spurred by events surrounding two controversial H5N1 transmission studies, a U.S. Senate committee [on Thursday] questioned federal officials whose agencies have a stake in dual-use research of concern (DURC) about the procedures they use to spot possible bioterror threats," CIDRAP News reports.

27 Apr 2012

Funders should follow lead of U.S. in creating policies for scientific research oversight

"The controversy over the research into the genetic modification of the H5N1 flu virus, finally approved for publication, should offer a reminder of the importance of debate" over dual-use technology, a Nature editorial states.

27 Apr 2012