Chloroquine News and Research

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Researchers develop set of tools to trace path of proteins linked to Parkinson's disease

As neurodegenerative disorders such as Parkinson's and Alzheimer's disease progress, misfolded proteins clump together in neurons, recruiting normal proteins in the cell to also misfold and aggregate.

4 Aug 2017

Researchers understand how to prevent severe weight loss in cancer patients

Many cancer patients are susceptible to potentially lethal weight loss. Now researchers understand better why this happens, and perhaps how to prevent the condition.

25 Jul 2017

Malaria drug effectively blocks Zika virus transmission to the fetus

Devastating consequences of Zika virus infection are suffered in the womb, where the virus can cause brain damage and sometimes death.

10 Jul 2017

NIH renews major grant for UW-led research center to understand malaria in India

The National Institutes of Health has renewed a major grant that funds a University of Washington-led research center to understand malaria in India.

20 Jun 2017

Brain cancer patient treated with malaria drug shows dramatic improvement

After her brain cancer became resistant to chemotherapy and then to targeted treatments, 26-year-old Lisa Rosendahl's doctors gave her only a few months to live.

19 Apr 2017

MIT biological engineers develop method to measure heme levels inside malaria parasite

The iron-containing molecule heme is necessary for life. Cells require heme to perform the chemical reactions that produce energy, among other critical tasks.

28 Feb 2017

Researchers discover set of immune proteins that facilitate long-lasting immunity against malaria

Houston Methodist researchers have discovered a set of immune proteins that facilitate long-lasting immunity against malaria.

7 Nov 2016

Achilles' heel of malaria parasite could be exploited to treat deadly disease

Malaria researchers at The Australian National University have found one of the malaria parasite's best weapons against drug treatments turns out to be an Achilles' heel, which could be exploited to cure the deadly disease.

25 Jul 2016

Researchers identify how sensory nerve receptors work together to transmit itch signals

Researchers have found how sensory nerve cells work together to transmit itch signals from the skin to the spinal cord, where neurons then carry those signals to the brain. Their discovery may help scientists find more effective ways to make itching stop.

20 Jul 2016

KARMA study confirms resistance to anti-malarial drugs confined to Southeast Asia

The first global mapping of artemisinin resistance has definitively confirmed that resistance to the main drug currently used in the treatment of Plasmodium falciparum malaria is for the moment confined to Southeast Asia and has not spread to sub-Saharan Africa.

24 Jun 2016

Dual-acting hybrid drug could be a promising new weapon against drug-resistant malaria

A combination of artemisinin and another drug (artemisinin combination therapy, ACT) is currently the best malaria treatment recommended by the World Health Organization.

12 Apr 2016

Competition between mixed malaria parasite strains could influence drug resistance

Scientists have documented for the first time how competition among different malaria parasite strains in human hosts could influence the spread of drug resistance.

23 Mar 2016

Researchers unravel biochemical action of antimalarial drug

Malaria is a worldwide menace. According to the Centers for Disease Control and Prevention, over 500,000 individuals died from malaria in 2013 alone. While treatments for the disease exist, cures can also take a hefty physical toll.

26 Feb 2016

Discovery may help researchers identify new ways to attack malaria parasite

New anti-malarial drugs could be developed after researchers discovered a new mechanism used by the malaria parasite when it infects humans.

21 Jan 2016

Turing Pharmaceuticals emphasizes continued availability of Daraprim

Turing Pharmaceuticals AG, a privately-held biopharmaceutical company focused on developing and commercializing innovative treatments for serious diseases and conditions, today emphasizes the continued availability of Daraprim and cautions healthcare providers of proposed alternatives to Daraprim.

20 Dec 2015

Mason researchers patent new breast cancer treatment

George Mason University researchers have patented a new breast cancer treatment that uses a common malaria drug to stop cancer in its beginning stages.

21 Nov 2015

Turing Pharmaceuticals acquires rights to market Daraprim (pyrimethamine) in the U.S.

Turing Pharmaceuticals AG today announced that it has acquired the exclusive rights to market Daraprim (pyrimethamine) in the U.S. from Impax Laboratories, Inc. The acquisition by Turing is part of a strategic effort focused on treatments for toxoplasmosis and other serious infectious diseases. The company also announced plans to invest in the development of new drug candidates for toxoplasmosis.

10 Aug 2015

Discovery brings hope for people suffering from Parkinson's disease

Scientists from Singapore's Nanyang Technological University and McLean Hospital and Harvard Medical School in the United States have found that existing anti-malaria drugs could be a potential treatment for Parkinson's disease.

16 Jul 2015

Scientists develop small molecule drug that prevents autophagy from starting in cancer cells

As a tumor grows, its cancerous cells ramp up an energy-harvesting process to support its hasty development. This process, called autophagy, is normally used by a cell to recycle damaged organelles and proteins, but is also co-opted by cancer cells to meet their increased energy and metabolic demands.

26 Jun 2015

Raising lupus awareness: an interview with Professor Ramsey-Goldman, MD

Lupus is a chronic, autoimmune disease, with many different symptoms so it is hard to diagnose. It affects each person differently and it has an unpredictable disease course with flare ups and quiet time. Some patients describe lupus as if they are riding a roller coaster with blinders on because they cannot always tell when they will feel well or sick...

11 May 2015