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FDA approves palbociclib combination for advanced HR-positive HER2-positive breast cancer

Today, Alliance Foundation Trials, LLC (AFT) was informed that the U.S. Food and Drug Administration has approved palbociclib in combination with trastuzumab, with or without pertuzumab, and endocrine therapy for adult patients with hormone receptor–positive (HR+), human epidermal growth factor receptor 2–positive (HER2+) locally advanced or metastatic breast cancer following induction treatment.

24 Jun 2026

New oral drug shows promise for chronic heart failure treatment

An early clinical study shows that a new oral drug is safe and well-tolerated in patients with chronic heart failure.

24 Jun 2026

First human bladder transplant patient thrives one year after surgery

One year after the first human bladder transplant, the patient is thriving and the UCLA Health surgeon who performed the operation already has completed a second successful bladder transplant, laying a solid path for a field of surgery that until now has not been feasible.

24 Jun 2026

Scientists identify genes linking air pollution to severe asthma

For many people with asthma, air-quality advisories are harbingers of worsening symptoms. But for reasons science has struggled to explain, the extent to which pollution exacerbates asthma varies widely from person to person.

24 Jun 2026

Functional brain imaging can help guide accelerated TMS for depression

Mass General Brigham study suggests that functional brain imaging can help guide accelerated transcranial magnetic stimulation for depression.

24 Jun 2026

AACR report highlights unequal burden of cancer in the United States

The American Association for Cancer Research (AACR) today released its Cancer Disparities Progress Report 2026, a comprehensive analysis of the unequal burden of cancer in the United States.

24 Jun 2026

USC study links modified Mediterranean diet to longer lifespan

A plant- and fish-based, low-protein diet paired with small amounts of an amino acid commonly found in eggs, meat and dairy increased healthy lifespan and decreased frailty and fat mass in mice, according to a new USC study published today in the journal Cell Metabolism.

23 Jun 2026

Landmark study confirms long-term durability of Ross procedure for aortic valve replacement

The Ross procedure, a highly specialized option for aortic valve replacement, is associated with significant long-term durability and excellent outcomes in a wide range of adult patients with aortic valve disease.

23 Jun 2026

Keck School of Medicine of USC and Novartis collaborate to eliminate breast cancer screening barriers

Compelled by disparities in breast cancer outcomes, the Keck School of Medicine of USC's Department of Population and Public Health Sciences and Novartis have joined forces in a pioneering collaboration to support medically underserved communities in Los Angeles County with the goal of eliminating barriers to screening and access.

23 Jun 2026

UCI Health launches world's first embryonic stem cell trial for Huntington's disease

UCI Health, the clinical enterprise of the University of California, Irvine, has opened the world's first in-human embryonic stem cell-derived clinical trial for Huntington's disease.

23 Jun 2026

Novel IL1RAP therapy advances toward pancreatic cancer clinical trial

Blocking IL1RAP, a receptor that sits at a key control point in inflammatory signaling, can disrupt the tumor-driven inflammatory network that helps pancreatic cancer resist treatment, according to new research.

22 Jun 2026

Using the mathematics of quantum mechanics to improve neuroblastoma outcomes

For a child diagnosed with neuroblastoma-the most common infant cancer, occurring when early nerve cells grow out of control-the path to treatment isn't simple.

22 Jun 2026

New vaccines successfully boost frontline immune cells against HIV

T-cells are the immune system's frontline defenders with a crucial role in controlling HIV. In a milestone clinical trial published in the Journal of Clinical Investigation, researchers with the UNC Institute for Global Health and Infectious Diseases (IGHID) at the UNC School of Medicine have demonstrated that new vaccines can significantly boost T cells targeting the most vulnerable, conserved regions of HIV-areas considered key to effective immune control.

22 Jun 2026

New drug could double survival time in patients with advanced pancreatic cancer

A new medication could double survival time in patients with advanced pancreatic cancer, according to Phase III clinical trial results presented at the American Society of Clinical Oncology (ASCO) 2026 annual meeting and simultaneously published in The New England Journal of Medicine.

22 Jun 2026

Pheno Therapeutics granted FDA IND clearance for lead multiple sclerosis therapeutic candidate PTD802

Pheno Therapeutics Limited. (Pheno), a clinical stage biotechnology company focused on the discovery and development of small molecule therapeutics for the treatment of neurological diseases, today announced that the US Food and Drug Administration (FDA) has cleared the Investigational New Drug (IND) application for PTD802, the Company's lead therapeutic candidate.

From Pheno Therapeutics 22 Jun 2026

Scientists develop wearable robotic system to restore hand function

Researchers at the Medical University of Vienna, in collaboration with ETH Zurich, the Technical University of Munich and Medical Faculty Belgrade, have developed a wearable neurorobotic system that combines electrical neurostimulation with hand exoskeletons.

19 Jun 2026

Preoperative radiation boosts immunotherapy response in brain metastases

A new study led by researchers at The University of Texas MD Anderson Cancer Center demonstrated that pre-operative radiation therapy for brain metastases not only targets tumor cells directly but also can activate immune pathways that can make tumors more receptive to immunotherapy.

17 Jun 2026

Trauma-focused therapy safely improves PTSD symptoms in psychosis patients

New research from the Institute of Psychiatry, Psychology & Neuroscience (IoPPN) at King's College London and published in The Lancet Psychiatry has found that people with psychosis experiencing Post Traumatic Stress Disorder (PTSD) can benefit from a Trauma-Focused therapy integrated with Cognitive Behavior Therapy for psychosis (CBTp).

17 Jun 2026

First human trial targets aging immune cells for healthier immunity

A first-in-human clinical trial of an immune rejuvenation therapy designed to restore the function of worn-out T cells is expected to begin later this year, building on research led by UCL scientists into the mechanisms of immune aging.

17 Jun 2026

AI-designed drug for Parkinson's begins first human trial

Insilico Medicine ("Insilico", HKEX: 3696), a clinical-stage biotechnology company powered by generative artificial intelligence (AI), today announced it has achieved the first clinical milestone in its co-development collaboration with Hygtia Therapeutics with the completion of first-in-human dosing in the Phase I study of ISM8969.

17 Jun 2026