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Study shows reduced bleeding risk with ticagrelor monotherapy after percutaneous coronary intervention

People who have had a heart attack or who are at risk for a heart attack and who stopped taking aspirin alongside the P2Y12 inhibitor ticagrelor one month after undergoing percutaneous coronary intervention (PCI) saw a significantly reduced risk of clinically meaningful bleeding with no increased risk of clotting-related adverse events at 12 months compared with patients who continued taking aspirin and ticagrelor for a full year, in a study presented at the American College of Cardiology's Annual Scientific Session.

8 Apr 2024

Ten doctors on FDA panel reviewing Abbott heart device had financial ties with company

When the FDA recently convened a committee of advisers to assess a cardiac device made by Abbott, the agency didn't disclose that most of them had received payments from the company or conducted research it had funded — information readily available in a federal database.

8 Apr 2024

Pioneering vaccine strategy promises to outmaneuver antimicrobial resistance

Study introduces Reverse Vaccine Development as a strategic approach to identify correlates of protection early in vaccine development against antimicrobial-resistant pathogens, aiming to mitigate risks such as significant phase-III clinical trial failures.

7 Apr 2024

Behavioral economics strategies boost daily walking by 10% in high-risk cardiovascular patients

Strategies such as earning points or small amounts of money encouraged people at high risk for heart disease or stroke to increase their daily walking by about 10% and sustain the increase for a year, according to research being presented at the American College of Cardiology's Annual Scientific Session.

7 Apr 2024

Hot climates worsen chronic kidney disease outcomes

Chronic kidney disease patients living in the hottest countries experienced an additional 8% drop in kidney function each year compared to those living in temperate climates, finds a new study from researchers at UCL and the London School of Hygiene & Tropical Medicine (LSHTM).

5 Apr 2024

Structured 'seizure action plan' can help patients with epilepsy to safely manage emergencies

A new 16-week study of 204 adult epilepsy patients found that 98% of participants believe that all patients with epilepsy should have a seizure action plan (SAP), regardless of seizure status.

5 Apr 2024

PeriCord bioimplants show promise in heart regeneration studies

The promising results obtained in a clinical trial with a pioneering advanced therapy drug named PeriCord, which aims to repair the heart of patients who have suffered a heart attack, confirm the feasibility of new therapies based on the application of stem cells and tissue engineering to promote the regeneration of damaged tissues.

5 Apr 2024

Mayo Clinic research shows health benefits of active workstations

A recent Mayo Clinic study suggests that active workstations incorporating a walking pad, bike, stepper and/or standing desk are successful strategies for reducing sedentary time and improving mental cognition at work without reducing job performance.

4 Apr 2024

BMI influences efficacy of nerve-stimulation treatment for sleep apnea, study finds

A nerve-stimulation treatment for obstructive sleep apnea that originally was approved only for people with body mass indexes (BMIs) in the healthy range recently was extended to patients with BMIs up to 40, a weight range generally described as severely obese.

4 Apr 2024

UCL and Oxford lead major dementia diagnosis trials

Thousands of people in the UK are to take part in countrywide trials to identify accurate and quick blood tests that can diagnose dementia, led by research teams at UCL and Dementias Platform UK, based at the University of Oxford.

4 Apr 2024

Rethinking exercise in post-COVID care

People suffering from post-COVID have been discouraged from exercising because early observations suggested it could be harmful.

4 Apr 2024

Telemedicine doubles HCV treatment success for opioid use disorder patients

People with opioid use disorder who have hepatitis C virus (HCV) were twice as likely to be successfully treated and cured from HCV if they received facilitated telemedicine treatment at their opioid treatment program (OTPs) than if they were referred off-site to another provider.

3 Apr 2024

Lurie Children's Hospital administers first gene therapy for Duchenne muscular dystrophy in Illinois

On March 27, 2024, Ann & Robert H. Lurie Children's Hospital of Chicago treated its first patient with ELEVIDYS (delandistrogene moxeparvovec-rokl), the first gene therapy for Duchenne muscular dystrophy – a rare, genetic disease characterized by progressive muscle damage and weakness.

3 Apr 2024

New model predicts kidney injury risk in cancer patients on cisplatin

Researchers have developed a new model predicting severe acute kidney injury in patients treated with cisplatin, incorporating factors like hypomagnesemia to improve patient care and outcomes.

3 Apr 2024

Defining how exercise affects cardiovascular health in people using wheelchairs

Delphia Brown (left) exercises at the Stephen A. Orthwein Center, a wheelchair-accessible gym in St. Louis operated by Paraquad, an organization that helps people with disabilities achieve independence.

2 Apr 2024

Understanding the genetics behind thyroid cancer to prevent unnecessary invasive treatments

Researchers at the University of Colorado School of Medicine are hopeful new research could prevent up to 130,000 unneeded fine-needle aspiration (FNA) biopsies of thyroid nodules and subsequent surgeries each year in the United States by better understanding the genetic risk associated with thyroid cancer.

1 Apr 2024

Stem cell therapy safe and potentially beneficial for spinal cord injury patients

A Mayo Clinic study shows stem cells derived from patients' own fat are safe and may improve sensation and movement after traumatic spinal cord injuries.

1 Apr 2024

Research suggests booster doses may be necessary for monkeypox immunity

New research to be presented at this year's European Congress of Clinical Microbiology and Infectious Diseases (ECCMID 2024) in Barcelona, Spain (27-30 April) shows that even in men who receives two doses of mpox vaccine intradermally, their level of antibodies to the virus falls to low or zero within the first few months if they have not received a previous smallpox vaccine.

1 Apr 2024

New study to test novel psychedelic compound as potential treatment for alcohol use disorder

Modern mental health company Clerkenwell Health announced today that it is working with clinical-stage biotechnology company Beckley Psytech on a Phase IIa study investigating whether a novel psychedelic compound, combined with psychological support, could be an effective treatment for alcohol use disorder (AUD).

29 Mar 2024

Vegan diet benefits individuals with type 1 diabetes, study shows

A low-fat vegan diet rich in fruits, vegetables, grains, and beans reduces insulin needs and improves insulin sensitivity and glycemic control in people with type 1 diabetes, according to a first-of-its-kind study by the Physicians Committee for Responsible Medicine published in Clinical Diabetes.

29 Mar 2024

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Clinical Trial News and Research

Study shows reduced bleeding risk with ticagrelor monotherapy after percutaneous coronary intervention

Ten doctors on FDA panel reviewing Abbott heart device had financial ties with company

Pioneering vaccine strategy promises to outmaneuver antimicrobial resistance

Behavioral economics strategies boost daily walking by 10% in high-risk cardiovascular patients

Hot climates worsen chronic kidney disease outcomes

Structured 'seizure action plan' can help patients with epilepsy to safely manage emergencies

PeriCord bioimplants show promise in heart regeneration studies

Mayo Clinic research shows health benefits of active workstations

BMI influences efficacy of nerve-stimulation treatment for sleep apnea, study finds

UCL and Oxford lead major dementia diagnosis trials

Rethinking exercise in post-COVID care

Telemedicine doubles HCV treatment success for opioid use disorder patients

Lurie Children's Hospital administers first gene therapy for Duchenne muscular dystrophy in Illinois

New model predicts kidney injury risk in cancer patients on cisplatin

Defining how exercise affects cardiovascular health in people using wheelchairs

Understanding the genetics behind thyroid cancer to prevent unnecessary invasive treatments

Stem cell therapy safe and potentially beneficial for spinal cord injury patients

Research suggests booster doses may be necessary for monkeypox immunity

New study to test novel psychedelic compound as potential treatment for alcohol use disorder

Vegan diet benefits individuals with type 1 diabetes, study shows

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