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Research identifies abnormal huntingtin protein critical for mitosis and cell fate determination

New research finds that a protein that is often mutated in Huntington's disease (HD) plays an unexpected role in the process of neurogenesis. The research, published by Cell Press in the August 12 issue of the journal Neuron, provides new insight into HD pathology and has even broader implications for human health and disease.

12 Aug 2010

Over-expression of Arpc1b promotes tumorigenic properties of breast cancer cells: Research

A major discovery, led by researchers from The George Washington University Medical Center, promises to revolutionize the way scientists think about key aspects of cellular lifecycle and offers a new avenue for cancer researchers to explore in their quest to one day slow down the progression of cancer.

21 Jul 2010

Insight into inner functional mechanisms of new bacterial infection target

In any battle, sizing up one's opponent is a critical first step. For researchers fighting a bacterial infection, that means assessing every nook and cranny of the malicious microorganism and identifying which ones to attack.

14 Jul 2010

Histone H1 phosphorylation involved in control of ribosomal RNA gene transcription

A protein that helps pack DNA into the cell nucleus has an important role in regulating gene activity, scientists report. The researchers found that the protein, histone H1, also takes part in the formation of ribosomes, the cellular workbenches on which all proteins are made.

2 Jul 2010

Researchers develop biosensors to monitor concentration of c-di-GMP within single living bacteria cells

Some species of bacteria perform an amazing reproductive feat. When the single-celled organism splits in two, the daughter cell - the swarmer - inherits a propeller to swim freely. The mother cell builds a stalk to cling to surfaces.

4 Jun 2010

Scientists discover key mechanism of cancer cells

Many tumor cells would not be viable due to aberrant chromosome distribution if they had not developed a special trick. Scientists from the German Cancer Research Center have investigated which genes are responsible for this survival strategy of cancer cells.

2 Jun 2010

UCSF scientists discover new stem cell in developing human brain

UCSF scientists have discovered a new stem cell in the developing human brain. The cell produces nerve cells that help form the neocortex - the site of higher cognitive function -- and likely accounts for the dramatic expansion of the region in the lineages that lead to man, the researchers say.

26 May 2010

Cellular IPOD plays role in prion biology

Cells take advantage of a biologically ancient compartment to sequester prions, an action that can initially prevent the prions’ phenotypic expression, according to Whitehead Institute researchers. While in this compartment, less heritable prion plaques mature to a more transmissible state.

27 Apr 2010

Research may help scientists understand the mechanism behind cellular differentiation

Multipotent stem cells have the capacity to develop into different types of cells by reprogramming their DNA to turn on different combinations of genes, a process called "differentiation."

6 Apr 2010

ImmunoCellular Therapeutics' dendritic cell-based vaccination with CSCs demonstrates survival benefits

ImmunoCellular Therapeutics, Ltd. announced today that its dendritic cell-based vaccination with cancer stem cells demonstrated a statistically significant survival benefit in a preclinical animal model of glioblastoma.

11 Mar 2010

Scientists develop new mathematical model to understand CML better

Doctors can now understand better chronic myeloid leukaemia (CML), including how it responds to therapy, thanks to a new mathematical model for the disease, developed by scientists in Portugal, Belgium and the United States. The work, to be published in the June edition of the journal Haematologica, also reveals that current therapies - which are not believed to cure CML - with the right protocol can actually get rid of the disease, and provides guidelines on how to do that.

21 Feb 2010

Ways of stem cells division linked to development of cancer

Changes in the way that stem cells divide in the gut could lead to cancer, according to a new study funded by the Bobby Moore Fund for Cancer Research UK.

20 Feb 2010

Mechanism by which Plasmodium replicates itself in human blood to spread disease identified

Malaria remains one of the most deadly infectious diseases. Yet, how Plasmodium, the malaria parasite, regulates its infectious cycle has remained an enigma despite decades of rigorous research.

19 Feb 2010

4SC AG announces the first treatment in Phase I clinical study of 4SC-205

4SC AG a drug discovery and development company focused on autoimmune and cancer indications, today announced the first treatment in a Phase I study evaluating 4SC-205, an oral Eg5 kinesin spindle protein inhibitor, in patients with solid tumours or malignant lymphomas.

11 Feb 2010

Researchers identify a key piece in the ageing process

Understanding how aged and damaged mother cells manage to form new and undamaged daughter cells is one of the toughest riddles of ageing, but scientists now know how yeast cells do it. In a groundbreaking study researchers from the University of Gothenburg, Sweden, show how the daughter cell uses a mechanical "conveyor belt" to dump damaged proteins in the mother cell.

2 Feb 2010

Discovery challenges understanding of blood cell development

University of Utah researchers led an international team of scientists that is the first to report on the previously undescribed ability of platelets to reproduce themselves in the circulation. Their revolutionary findings were published online Jan. 19, 2010, in the journal Blood.

27 Jan 2010

Daughter Cell News and Research

Research identifies abnormal huntingtin protein critical for mitosis and cell fate determination

Over-expression of Arpc1b promotes tumorigenic properties of breast cancer cells: Research

Insight into inner functional mechanisms of new bacterial infection target

Histone H1 phosphorylation involved in control of ribosomal RNA gene transcription

Researchers develop biosensors to monitor concentration of c-di-GMP within single living bacteria cells

Scientists discover key mechanism of cancer cells

UCSF scientists discover new stem cell in developing human brain

Cellular IPOD plays role in prion biology

Research may help scientists understand the mechanism behind cellular differentiation

ImmunoCellular Therapeutics' dendritic cell-based vaccination with CSCs demonstrates survival benefits

Scientists develop new mathematical model to understand CML better

Ways of stem cells division linked to development of cancer

Mechanism by which Plasmodium replicates itself in human blood to spread disease identified

4SC AG announces the first treatment in Phase I clinical study of 4SC-205

Researchers identify a key piece in the ageing process

Discovery challenges understanding of blood cell development

CSHL scientist discovers how bookmarking protein triggers leukemia

New stem cell based technology may eliminate brain cancer

New technology sheds light on intracellular transport

Typical smoker acquires one mutation for every 15 cigarettes and all cancers are caused by mutations

Industry Focus eBook - Cell & Gene Therapy (1st Edition) eBook

Advancing Intracellular Delivery with LumiPore®

How ELRIG Is Helping Mid-Career Scientists Navigate Leadership, Career Change and Redundancy

The role of UV-Vis in biopharma QC

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