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Low-cost biosensor identifies altered protein levels associated with psychiatric disorders

Brazilian researchers have developed a low-cost, portable biosensor that can quickly identify a protein whose altered levels are associated with psychiatric disorders, such as depression, schizophrenia, and bipolar disorder.

30 Oct 2025

Unlocking the secrets of NMDA receptors for better brain health

As information zings from cell to cell inside the brain, bursts of electricity spur its transmission. At Cold Spring Harbor Laboratory (CSHL), scientists have turned their attention to the tiny pores that let charged ions enter a cell-and the molecular gatekeepers that help control them.

29 Oct 2025

Scientists uncover the gut’s hidden hydrogen engine and how it falters in Crohn’s disease

Study reveals that group B [FeFe]-hydrogenase is the primary enzyme driving fermentative hydrogen production in the healthy human gut, mainly through Bacteroides species. These genes are significantly depleted in Crohn’s disease, indicating a metabolic shift and altered hydrogen cycling dominated by respiratory bacteria

27 Oct 2025

Mitochondria and lysosomes work together to control regulatory T cell activation

Metabolism guides the activation states of regulatory T cells, the immune cells that prevent inappropriate activation of the immune system.

24 Oct 2025

New insight into TRPM3 heat sensor reveals how the body detects temperature

The ability to sense heat protects the body from burns and injury. But how the body actually feels temperature has remained an elusive mystery.

24 Oct 2025

Unveiling the dual role of HIV integrase in viral replication

The rate of HIV infection continues to climb globally. Around 40 million people live with HIV-1, the most common HIV strain.

24 Oct 2025

Study reveals protein plaques in neurodegeneration function as enzymes, breaking down ATP

A new study led by Rice University's Pernilla Wittung-Stafshede has revealed that protein clumps, or plaques that clog the brain, associated with Parkinson's disease are not merely waste; they can actively drain energy from brain cells.

21 Oct 2025

Scientists discover why a powerful leukemia drug fails in most patients

Researchers from Rutgers Health and other institutions have discovered why a powerful leukemia drug eventually fails in most patients – and found a potential way to overcome that resistance.

17 Oct 2025

What happens when microplastics reach the testes? Study shows autophagy and cell loss

Researchers found that microplastics from everyday plastic tableware accumulate in human semen and, although not linked to semen quality in the full cohort, were associated with altered sperm parameters in specific subgroups. Experimental models confirmed that 50 nm polystyrene particles trigger autophagy and apoptosis via the FOXA1/MAP3K1/p38 pathway, impairing sperm structure and function.

15 Oct 2025

Revolutionary structures show how chaperone proteins prevent diseases caused by protein misfolding

The first full-length structures of two heat shock chaperone proteins in a complex reveal the key structural region regulating their function, according to a new study from St. Jude Children's Research Hospital.

15 Oct 2025

From street to lab: Advancing controlled substance testing with handheld Raman and FTIR

Discover how Thermo Fisher’s handheld Raman and lab FTIR tools are transforming controlled substance testing with safer, faster, and more reliable results.

From Thermo Fisher Scientific – Pharmaceutical and Biopharmaceutical Solutions 14 Oct 2025

New insights into malaria proteins offer pathway to blocking parasite transmission

Using millions of microscope images magnified up to 130,000 times, researchers from Radboud university medical center and Toronto have unraveled the structure of two key proteins in the malaria parasite.

10 Oct 2025

New NMR technique reveals atomic-scale motion in catalytic enzyme function

Researchers from Tokyo Metropolitan University have developed a new structure determination method using Nuclear Magnetic Resonance (NMR) spectroscopy which shows how different parts of complex molecular machinery like enzymes move while they help catalyze reactions.

6 Oct 2025

Thermo Fisher Scientific expands neurodegeneration research capabilities with launch of Olink® Target 48 Neurodegeneration panel

Thermo Fisher Scientific Inc., the world leader in serving science, today announced the launch of the Olink® Target 48 Neurodegeneration panel, a high-performance, targeted proteomics immunoassay panel developed to accelerate discoveries in neurodegenerative disease research.

From Olink®- Part of Thermo Fisher Scientific 3 Oct 2025

How the University of Manchester used Bruker equipment to map the dynamics of complex protein

Discover how Bruker and the University of Manchester joined forces to discover more on the dynamics of complex protein.

From Bruker BioSpin Group 2 Oct 2025

Uganda’s most vulnerable region faces high Salmonella burden

In the dry, isolated area of Karamoja in northeastern Uganda – the country’s poorest sub-region – children have long suffered from malnutrition and water shortages.

26 Sep 2025

Scientists map step-by-step activation of brain receptors

When it comes to brain proteins, small changes can make a dramatic difference. Researchers studying NMDA (N-methyl-D-aspartate) receptors, which are essential for learning, memory and moment-by-moment consciousness, know that even slight changes in their activity level can mean the difference between normal function and serious neurological disorders.

24 Sep 2025

Cryo-EM reveals how blood clotting proteins fit together to trigger clot formation

If you've ever accidentally sliced yourself on a broken glass or a piece of paper, you may have noticed that the bleeding can be hard to stop.

13 Sep 2025

Texas Tech research team earns $3 million renewal to advance stroke therapy

Stroke research aims to understand the brain's self-protective and repair mechanisms. Gaining detailed insight into these mechanisms is crucial as such knowledge could lead to newly developed medications and interventions which mimic or engage the brain's self-protective/repair mechanisms, leading to innovative stroke therapies.

13 Sep 2025

Novel method accurately identifies therapeutic antibodies to treat infectious diseases

Scientists at Scripps Research have developed a novel method that uses artificial intelligence (AI) and advanced imaging techniques to more accurately and efficiently identify therapeutic antibodies to treat infectious diseases.

10 Sep 2025

Electron News and Research

Low-cost biosensor identifies altered protein levels associated with psychiatric disorders

Unlocking the secrets of NMDA receptors for better brain health

Scientists uncover the gut’s hidden hydrogen engine and how it falters in Crohn’s disease

Mitochondria and lysosomes work together to control regulatory T cell activation

New insight into TRPM3 heat sensor reveals how the body detects temperature

Unveiling the dual role of HIV integrase in viral replication

Study reveals protein plaques in neurodegeneration function as enzymes, breaking down ATP

Scientists discover why a powerful leukemia drug fails in most patients

What happens when microplastics reach the testes? Study shows autophagy and cell loss

Revolutionary structures show how chaperone proteins prevent diseases caused by protein misfolding

From street to lab: Advancing controlled substance testing with handheld Raman and FTIR

New insights into malaria proteins offer pathway to blocking parasite transmission

New NMR technique reveals atomic-scale motion in catalytic enzyme function

Thermo Fisher Scientific expands neurodegeneration research capabilities with launch of Olink® Target 48 Neurodegeneration panel

How the University of Manchester used Bruker equipment to map the dynamics of complex protein

Uganda’s most vulnerable region faces high Salmonella burden

Scientists map step-by-step activation of brain receptors

Cryo-EM reveals how blood clotting proteins fit together to trigger clot formation

Texas Tech research team earns $3 million renewal to advance stroke therapy

Novel method accurately identifies therapeutic antibodies to treat infectious diseases

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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