Genomic News and Research

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Hidden junk DNA could play decisive role in cancer

Many repetitive regions of the genome have been considered "junk DNA" because the technologies available did not allow them to be studied at sufficient resolution.

5 Jun 2026

Novel technology maps single-cell DNA-protein interactions

A new technology allows scientists to map, in single cells, the DNA binding sites of transcription factors and other regulatory proteins that control gene activity, according to a study led by investigators at Weill Cornell Medicine and the New York Genome Center.

4 Jun 2026

Diverse cancer subtypes can originate from a single progenitor cell

How do different cancer subtypes arise? Do they originate from distinct cells, or from a single multipotent cell capable of differentiating into multiple cell types?

4 Jun 2026

New manufacturing platform produces targeted mixtures of beneficial gut bacteria

Researchers at the Icahn School of Medicine at Mount Sinai have developed a new manufacturing platform for producing targeted mixtures of beneficial gut bacteria, an approach that could help expand access to microbiome-based therapies for patients with recurrent Clostridioides difficile (C. difficile) infection.

3 Jun 2026

Scientists introduce a precise framework to study screen-saturated childhoods

Children are growing up inside screens. A new peer-reviewed Thought Leaders Invited Review in Brain Health argues that neuroscience has been missing the word for what those screens are touching.

3 Jun 2026

How dysregulated collagen IV homeostasis causes cerebral microbleeds

Millions of older adults have tiny brain hemorrhages called cerebral microbleeds, which are strongly associated with dementia, cognitive decline, and stroke.

2 Jun 2026

Pediatric experts reveal the 10 research areas set to shape child health

Pediatric research leaders identified 10 high-promise areas likely to shape child health over the next 5 to 10 years, including genomics, mental health, vaccines, artificial intelligence, perinatal medicine, precision therapeutics, health equity, nutrition, environmental health, and cancer treatment. The paper argues that these opportunities will only translate into better outcomes if pediatric research receives sustained funding, public trust, workforce support, advocacy, and equitable implementation.

1 Jun 2026

Genetic testing identifies cause of pancreatic agenesis in infants

The DNA changes responsible for a rare genetic condition causing babies to be born without a pancreas can now be identified in almost all affected children through genetic testing.

1 Jun 2026

Brazilian study links TP53 mutations to poor lung cancer prognosis

Lung cancer is the most common and deadly form of cancer worldwide. It is increasingly understood to be a complex genetic disease with different mutations that vary according to factors such as smoking and ethnicity.

1 Jun 2026

New SMArT platform improves safety of CRISPR gene editing

A team of researchers led by Luigi Naldini at the San Raffaele Telethon Institute for Gene Therapy (SR-Tiget) has developed a new strategy to significantly improve the precision and safety of CRISPR-Cas9 gene editing in human blood stem cells, potentially overcoming one of the major barriers limiting broader clinical application of genome editing therapies.

1 Jun 2026

Enhancing reproducibility in genomics workflows with magnetic bead-based extraction

In this interview, Dr Dagmara Lewandowska talks about innovations in magnetic bead-based extraction and genomics automation.

From INTEGRA Biosciences 1 Jun 2026

Mesenchymal drift may explain how aging cells lose their identity

Mesenchymal drift may help explain how cells lose stable identity and acquire pro-fibrotic, inflammatory mesenchymal traits during aging. The review proposes MD as a unifying framework that links multiple hallmarks of aging and highlights partial reprogramming as a potential, but still preclinical, way to counteract this process.

1 Jun 2026

Gene test helps many breast cancer patients avoid chemotherapy

Many people with breast cancer can safely avoid chemotherapy with the use of a gene test, potentially sparing them unnecessary side effects without increasing the risk of the cancer returning, a large international clinical trial led by UCL has found.

29 May 2026

4basebio launches high-performance enzymatic ssDNA platform to accelerate next-generation gene editing

4basebio PLC, a specialist in synthetic DNA manufacturing and nucleic acids for next-generation therapeutics, announces the commercial launch of its high-capacity single-stranded DNA (ssDNA) product line to accelerate the development of safer, more precise genetic therapies by enabling targeted gene editing, advanced cell engineering, and innovative nucleic acid-based medicines.

From 4basebio PLC 29 May 2026

AI-powered atlas maps immune structures across multiple cancer types

In a new study published today in Science, researchers from The University of Texas MD Anderson Cancer Center developed a spatial atlas of specialized immune structures, called tertiary lymphoid structures (TLSs), across multiple cancer types.

28 May 2026

Extreme trait values often have simpler genetic explanations than thought

Researchers at the Icahn School of Medicine at Mount Sinai have found evidence that people who fall at the extreme high or low ends of certain traits, such as cholesterol, blood glucose, height, and age at menopause, are more likely to have a simple genetic explanation than previously thought.

27 May 2026

New AI model predicts cancer treatment responses from mutations

Researchers at University of California San Diego have developed a new artificial intelligence (AI) model that can translate a tumor's complex genetic profile into predictions about how that cancer may respond to treatment.

26 May 2026

New AI model detects hidden antibiotic resistance genes beyond standard databases

resLens uses genomic language models to detect antibiotic resistance genes from DNA sequences, performing especially well on long-read data and on some ARGs poorly represented in reference databases.

25 May 2026

New advances improve prevention and treatment of HPV-related cancers

A new review article is drawing attention to the growing global impact of human papillomavirus (HPV) and the rapid progress in vaccines and therapeutic strategies aimed at reducing the burden of cervical and non-cervical cancers.

24 May 2026

DNA methylation variability may improve precision cancer treatment strategies

A new review article brings attention to the critical role of DNA methylation heterogeneity in shaping the tumor microenvironment, highlighting its growing importance in understanding cancer progression and advancing more precise treatment strategies.

24 May 2026