Large Intestine News and Research

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Unhealthy gut microbes play role in development of high blood pressure in rats

Researchers have found that the microorganisms residing in the intestines (microbiota) play a role in the development of high blood pressure in rats. The study is published in Physiological Genomics. It was chosen as an APSselect article for February.

3 Feb 2017

UT Southwestern scientists discover gene that protects gut from IBD

UT Southwestern Medical Center researchers have identified a gene that protects the gut from inflammatory bowel disease.

2 Feb 2017

Oral dose of phage cocktail prevents infection and cholera-like symptoms in animal model

Oral administration of a cocktail of three viruses, all of which specifically kill cholera bacteria, prevents infection and cholera-like symptoms in animal model experiments, report scientists from Tufts University School of Medicine and the Sackler School of Graduate Biomedical Sciences at Tufts in Nature Communications on Feb. 1.

1 Feb 2017

Study shows evidence that intestinal microorganisms can serve as link between diet and colorectal cancer

A new study provides some of the strongest evidence to date that microorganisms living in the large intestine can serve as a link between diet and certain types of colorectal cancer, the lead authors at Dana-Farber Cancer Institute and Massachusetts General Hospital report.

28 Jan 2017

Study provides fundamental insights into functioning of microbiota and human-gut flora symbiosis

The researchers, led by Professor Bert van den Berg and Dr. David Bolam from the Institute of Cell and Molecular Biosciences at Newcastle University and with support from collaborators at Jacobs University Bremen, report on their findings today in Nature.

12 Jan 2017

New review provides insights on rates, predictors of relapse after surgery in Crohn's disease patients

Some patients with Crohn's disease, a chronic inflammatory disease that affects the lining of the digestive tract, require surgery to remove part or all of the large intestine; however, surgery does not cure the condition and many patients relapse after surgery.

8 Dec 2016

NSF awards grant to advance new diagnostic test for fatal gastrointestinal disease in pre-term infants

The National Science Foundation has chosen an LSU Health New Orleans team that developed a test for the early detection of a potentially life-threatening gastrointestinal disease affecting pre-term, low birthweight babies to receive expert guidance to move the technology forward.

1 Dec 2016

Arthritis drug induces response and remission in patients with Crohn's disease, study finds

Researchers at University of California San Diego School of Medicine have shown that ustekinumab, a human antibody used to treat arthritis, significantly induces response and remission in patients with moderate to severe Crohn's disease.

17 Nov 2016

WSU researchers identify potential new diagnostic tool for early detection of colorectal cancer

Scientists at Washington State University and Johns Hopkins Medical School have discovered a fast, noninvasive method that could lead to the early diagnosis of colorectal cancer.

25 Oct 2016

Factors secreted by intestinal bacteria may help prevent or treat kidney stones

Researchers have discovered that factors secreted by gut bacteria might help prevent or treat kidney stones.

14 Oct 2016

Research opens up new ways to detect, inhibit cancer spread

Clusters of circulating cells commonly found in the blood of cancer patients have long been the subject of research on cancer. These clusters have been regarded for more than 50 years as malignant cells that have broken off from the primary tumor, spreading cancer to other parts of the body.

8 Jul 2016

Enzyme from fermented Japanese vegetable boosts colon health in rats

An enzyme produced by fermenting a vegetable common in Japanese cuisine may be responsible for increasing the amount of at least one beneficial bacterium associated with healthy colons in a study using rats.

4 Jul 2016

Home test using paper strips could help detect cancer, malaria

What if testing yourself for cancer or other diseases were as easy as testing your blood sugar or taking a home pregnancy test? In a few years, it might be.

29 Jun 2016

Siemens Healthineers' new CT and MRI technologies to aid research across various common clinical pathways

The Transforming Outcomes and Health Economics Through Imaging (TOHETI) programme is looking to change the way medical imaging works by undertaking a range of pioneering research.

24 Jun 2016

Researchers unravel species-function relationships in gut microbial genomes

Despite recent progress, the organization and ecological properties of the intestinal microbial ecosystem remain under investigated. Using a manually curated metabolic module framework for (meta-)genomic data analysis, Sara Vieira-Silva, Gwen Falony and colleagues from the Jeroen Raes lab studied species-function relationships in gut microbial genomes and microbiomes.

14 Jun 2016

Certain sugars in the body play key role in colitis, colon cancer development

An Oklahoma Medical Research Foundation scientist has discovered that certain sugars produced by the body play an important role in the development of colitis and, ultimately, colon cancer. The new finding could potentially lead to therapies for ulcerative colitis, Crohn's disease and colon cancer.

5 May 2016

Antibiotic treatment may allow bad bugs to flourish

Antibiotics are essential for fighting bacterial infection, but, paradoxically, they can also make the body more prone to infection and diarrhea.

3 May 2016

Substances from tequila plant may help treat osteoporosis

Mexican scientist identified substances from the plant that enhance absorption of calcium in the body.

11 Apr 2016

Reminder letters for bowel scope screening could boost more participation

JOGGING the memory with a reminder letter to those who don't respond to their bowel scope screening invitation could mean more people would take the test, according to a Cancer Research UK-funded study published in the British Journal of Cancer today.

30 Mar 2016

Prognostic test could help lower cancer recurrence for colorectal patients

Colorectal cancer, one of the most commonly diagnosed cancers in the United States, is not a commonly discussed disease. Often symptomless in early stages, the cancer is more difficult to treat as it progresses, requiring chemotherapy in later stages. Researchers at the University of Notre Dame are working on a way to identify patients who would benefit from chemotherapy before the cancer progresses.

15 Mar 2016