Neurosurgery News and Research

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Promising results seen in atypical trigeminal neuralgia with combined surgical approach

Atypical trigeminal neuralgia (ATN) is a chronic pain condition characterized by persistent facial pain that does not respond well to conventional medical treatments, often leading to significant impairment in quality of life.

25 Apr 2025

Rethinking stroke prevention for patients with mild carotid narrowing

Ischemic stroke remains one of the leading causes of death and long-term disability worldwide, with narrowing of the carotid artery due to atherosclerosis contributing to up to 30% of all cases.

24 Apr 2025

Study reveals how medulloblastoma spreads and grows on the leptomeninges

Researchers at Baylor College of Medicine, Texas Children's Hospital, the Hospital for Sick Children in Toronto and collaborating institutions reveal in Nature Cell Biology a strategy that helps medulloblastoma, the most prevalent malignant brain tumor in children, spread and grow on the leptomeninges, the membranes surrounding the brain and spinal cord.

22 Apr 2025

Stem cell therapy shows promise for treating advanced Parkinson's disease

A stem cell–based therapy initially developed at Memorial Sloan Kettering Cancer Center (MSK) may lead to a new treatment for advanced Parkinson's disease, according to results from a phase 1 clinical trial reported in Nature.

16 Apr 2025

Study sheds light on brain regions involved in logical thinking

A team of researchers at UCL and UCLH have identified the key brain regions that are essential for logical thinking and problem solving.

16 Apr 2025

Lower LDL cholesterol linked to reduced dementia risk

Researchers investigate the potential association between LDL-C levels and the risk of dementia.

7 Apr 2025

Study identifies 17 modifiable risk factors shared between stroke, dementia, and depression

Age-related brain diseases such as stroke, dementia, and late-life depression are a debilitating part of growing older, but people can lower their risk of these diseases through behavioral and lifestyle changes.

3 Apr 2025

Study links low LDL-C levels to reduced risk of dementia

People with low levels of low-density lipoprotein cholesterol (LDL-C) in their blood have a lower risk of dementia, including lower risk of Alzheimer's disease related dementia, shows a study published online today in the Journal of Neurology Neurosurgery & Psychiatry.

1 Apr 2025

ALL ALS Consortium creates a central information hub to accelerate ALS research

The Access for All in ALS (ALL ALS) Consortium announced the launch of its official website, creating a central hub for information about its initiatives and clinical research studies. ALL-ALS.org is designed to inform and engage researchers, clinicians, and current and prospective study participants.

31 Mar 2025

New drug combination shows promise in treating melanoma brain metastasis

A federally funded research team led by Sheri Holmen, PhD, investigator at Huntsman Cancer Institute and professor in the Department of Surgery at the University of Utah (the U), is testing a new combination drug therapy that could both treat and prevent melanoma metastasis, or spreading from its original site, to the brain.

21 Mar 2025

Elderly neurological patients show willingness accept home-based remote monitoring

A recent study by the University of Eastern Finland Business School indicates that elderly neurological patients show a willingness to accept remote monitoring (RM) in the home environment even in the pre-implementation phase.

21 Mar 2025

Yale scientists develop advanced CRISPR tool to study complex genetic interactions

Advances in the gene-editing technology known as CRISPR-Cas9 over the past 15 years have yielded important new insights into the roles that specific genes play in many diseases.

20 Mar 2025

Deep brain stimulation shows promise for reducing self-injurious behavior in children with autism

Severe self-injurious behavior in children with autism spectrum disorder (ASD) poses a significant risk of permanent physical injury.

20 Mar 2025

Study identifies brain areas crucial for word memory in epilepsy

The parts of the brain that are needed to remember words, and how these are affected by a common form of epilepsy, have been identified by a team of neurologists and neurosurgeons at UCL.

19 Mar 2025

Cambridge and London hospitals to pioneer brain implants to combat alcohol and opioid addiction

People suffering from severe alcohol and opioid addiction are to be offered a revolutionary new technique involving planting electrodes in the brain to modulate brain activity and cravings and improve self-control.

19 Mar 2025

FDA-approved drug for chronic kidney disease may help mitigate antibiotic resistance

Increased antibiotic use can lead, seemingly paradoxically, to more problematic infections, as the bacteria evolve to resist the treatment.

18 Mar 2025

New research reveals potential path forward for glioblastoma treatment

Glioblastoma has remained one of the toughest cancers to treat, resisting even the latest advances in immunotherapy.

17 Mar 2025

New method enhances precision in monitoring brain activity during deep brain stimulation

Mayo Clinic researchers have found a new way to more precisely detect and monitor brain cell activity during deep brain stimulation, a common treatment for movement disorders such as Parkinson's disease and tremor.

14 Mar 2025

Study investigates genetic mutations linked to occupational exposures

Occupational and environmental exposures can put specific groups of people at higher risk of cancer, including firefighters. A new study by investigators at Mass General Brigham examines a cancer rarely studied in firefighters: gliomas-a type of tumor that forms in the brain or spinal cord.

11 Mar 2025

Phase 1 trial examines safety and feasibility of stem cell treatment for Parkinson's

A recently launched Phase 1 clinical trial at Mass General Brigham is examining the safety and feasibility of a groundbreaking treatment approach for Parkinson's disease in which a patient's stem cells are reprogrammed to replace dopamine cells in the brain damaged by the disease.

6 Mar 2025