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Researchers create the first 'living medicine' to treat drug-resistant lung infections

Researchers have designed the first 'living medicine' to treat lung infections. The treatment targets Pseudomonas aeruginosa, a type of bacteria which is naturally resistant to many types of antibiotics and is a common source of infections in hospitals.

19 Jan 2023

University adopts INTEGRA pipettes for prestigious international competition

Students of Technische Universität Braunschweig, Germany, used INTEGRA Biosciences’ VIAFLO electronic pipettes and EVOLVE manual pipettes to perform sample transfers and dilutions as part of their project for the 2022 iGEM competition.

From INTEGRA Biosciences 12 Jan 2023

UC San Diego researchers rewrite the textbook on gene regulation

A fundamental principle of molecular biology governs how proteins are made within the cell, which happens in two stages called transcription and translation.

22 Dec 2022

Using synthetic gene circuits to better control the timing of immunotherapy

In two separate studies, researchers demonstrate how synthetic biology can be used to tackle a difficult issue in cancer immunotherapy: the way immunotherapy-related approaches focused on short-term killing of tumor cells may fail to eradicate tumors because growth of tumors happens on longer timescales.

16 Dec 2022

Exploring synthetic engineering of bacteriophages

In a new study, researchers demonstrated biological bacteriophage containment and synthetic engineering.

24 Nov 2022

New therapeutic windows for developing effective treatments for metastatic tumors

Cancer that splits and develops in new organs around the body becomes significantly more difficult to fight. Now, researchers at Chalmers University of Technology, Sweden, have shown that these metastatic cancers, that spread from the original, adapt their metabolism to the tissue in which they grow. The discovery represents a breakthrough for the understanding of metastatic cancer and is an important piece of the puzzle in the search for more effective treatments.

17 Nov 2022

Cambridge scientists use synthetic biology approach to destroy SARS-CoV-2 virus

Cambridge scientists have used synthetic biology to create artificial enzymes programmed to target the genetic code of SARS-CoV-2 and destroy the virus, an approach that could be used to develop a new generation of antiviral drugs.

16 Nov 2022

ELRIG: Bringing Life Sciences and Drug Discovery Communities Together

We spoke to ELRIG about the evolving landscape of the drug discovery sector, and what actions they are taking to continue to support individuals in this space.

11 Nov 2022

New method to estimate the contribution of each amino acid residue

You can't expect a pharmaceutical scientist to switch labs to the facilities available in a television studio and expect the same research output. Enzymes behave exactly the same. But now, in a study recently published in ACS Synthetic Biology, researchers from Osaka University have imparted an analogous level of adaptability to enzymes, a goal that has remained elusive for over 30 years.

3 Nov 2022

New control system could be used to finely tune the production of useful proteins

Using an approach based on CRISPR proteins, MIT researchers have developed a new way to precisely control the amount of a particular protein that is produced in mammalian cells.

1 Nov 2022

Using magnetic bacteria to fight cancerous tumors

Researchers at ETH Zurich are planning to use magnetic bacteria to fight cancerous tumors. They have now found a way for these microorganisms to effectively cross blood vessel walls and subsequently colonize a tumor.

26 Oct 2022

Researchers identify a natural defense mechanism that protects cells from Pseudomonas infection

Pseudomonas aeruginosa (P.a.) are resistant to most antibiotics and cause life-threatening infections of wounds or the lungs.

21 Oct 2022

Light-Seq technology for barcoding and deep-sequencing selected cell populations in tissues

Under the microscope, researchers often observe different cell types organizing themselves in peculiar patterns within tissues, or sometimes a rare cell type that stands out by occupying a unique position, exhibiting an unusual shape, or expressing a specific biomarker molecule.

10 Oct 2022

Study establishes a feasible combination therapeutic strategy for ulcerative colitis

Despite recent advancements in our knowledge of the pathogenic mechanisms of ulcerative colitis, there is still a considerable unmet medical need for the treatment of ulcerative colitis.

29 Sep 2022

Scientists visualize antibiotics in action inside a pathogenic bacterium

Every living cell relies on proteins in order to function and the process of protein synthesis – translation – is critical for survival.

28 Sep 2022

Scientists harness the potential of bacteria to help create synthetic cells with lifelike functionality

Scientists have harnessed the potential of bacteria to help build advanced synthetic cells which mimic real life functionality.

14 Sep 2022

Evonetix commences early access program for DNA synthesised by thermal control on its semiconductor chip

Researchers are invited to apply to receive DNA that has been synthesised using Evonetix’s platform.

From Evonetix 16 Aug 2022

Scientists explore ecological firewalls for the containment of synthetic microbes

In a new study, researchers described ecological firewalls (EFWs) to contain synthetic microbes.

10 Aug 2022

Using native microbes as chassis for transgene delivery in live bacterial therapeutics

Residing within the human gut are trillions of bacteria and other microorganisms that can impact a variety of chronic human ailments, including obesity, type 2 diabetes, atherosclerosis, cancer, non-alcoholic fatty liver disease and inflammatory bowel disease.

4 Aug 2022

Study defines how cannabis cells make cannabinoids

For the first time, plant biologists have defined the high-efficiency "hacks" that cannabis cells use to make cannabinoids (THC/CBD). Although many biotechnology companies are currently trying to engineer THC/CBD outside the plant in yeast or cell cultures, it is largely unknown how the plant does it naturally.

3 Aug 2022