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Exploring receptor-blocking conserved non-neutralizing antibodies for SARS-CoV-2 therapy

In a new study, researchers hypothesized and developed broad-spectrum SARS-CoV-2 inhibitors, ReconnAbs, by modifying the existing non-neutralizing antibodies targeted towards the highly conserved epitopes of the SARS-CoV-2 spike (S) protein combined with a receptor-blocking component.

28 Jan 2022

Intranasal interferon-λ treatment protects mice against SARS-CoV-2 Beta and Omicron variants

Researchers investigate the possible efficacy of IFN-λ in the context of SARS-CoV-2 infection in mice.

28 Jan 2022

Low Dead Volume Reservoir Trays

Precision manufactured to SBS / SLAS dimensions - Porvair Sciences range of reservoir trays are designed for simple integration with any robotic liquid handling system.

From Porvair Sciences Limited 28 Jan 2022

Early-stage alveolar epithelial cell necrosis linked to COVID-19-induced acute respiratory distress syndrome

A new study analyzed whether alveolar epithelial cell necrosis at an early stage SARS-CoV-2 infection and subsequent releases of damage-associated molecular patterns could aggravate COVID-19-associated acute respiratory distress syndrome.

27 Jan 2022

SARS-CoV-2 mutations and their impact on spike protein-specific T lymphocytes

New research assesses the impact of mutations in SARS-CoV-2 variants of concern (VOCs) on the T lymphocytes, specifically to the spike (S) protein of SARS-CoV-2.

27 Jan 2022

Study suggests enhanced phosphorylation and increased abundance of SARS-CoV-2 nucleocapsid protein provide selective advantage

Researchers have been investigating the phosphorylation of the nucleocapsid protein.

27 Jan 2022

Recipients of inactivated COVID-19 vaccine (CoronaVac) can be successfully boosted with different vaccines

In the recently published study in The Lancet, first-authored by Dr. Sue Ann Costa Clemens from the University of Oxford in the United Kingdom and the University of Siena in Italy, a comprehensive analysis has been pursued on the immunogenicity and safety of both homologous and heterologous boosting after receiving the inactivated vaccine CoronaVac.

26 Jan 2022

T-cell apoptosis linked to poor prognosis among COVID-19 patients

Researchers assess the probability of T-cell apoptosis in patients with severe COVID-19 who were admitted to the hospital.

26 Jan 2022

Study shows enduring T-cell immunity up to at least 1-year after SARS-CoV-2 infection

A new study assesses SARS-CoV-2 antigen-specific cytokine responses in a cohort of SARS-CoV-2 infected individuals with varying levels of disease.

26 Jan 2022

Cross-recognition of SARS-CoV-2 vaccine-elicited T cell responses among different variants

In a new study, researchers evaluated SARS-CoV-2 vaccination-induced T cell responses cross-recognition among the early and novel SARS-CoV-2 variants.

26 Jan 2022

Antibodies against SARS-CoV-2 found to persist for up to 15 months after infection

In a new study, a team of researchers explored the association between total immunoglobulin (IgM, IgA, and IgG) against SARS-CoV-2 and protective immunity.

26 Jan 2022

The Role of Glycans in the Cell and Glycans Imaging Method

In this interview, News-Medical talks to a pioneer of glycan imaging, Richard Drake about glycans, their role in maintaining cellular homeostasis, glycopeptide analysis, and method development for glycan imaging.

From Bruker Daltonics 26 Jan 2022

Anti-SARS-CoV-2 antibodies found in wild mustelids in France

A new study focused on the identification of SARS-CoV-2 infection in wild mustelids in the French region of Brittany.

26 Jan 2022

Research says spill-over of SARS-CoV-2 from humans to cattle is possible

In a recent study posted to the bioRxiv* preprint server, a team of researchers assessed the risk of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) transmission from humans to cattle.

26 Jan 2022

SARS-CoV-2 virus co-opts intrinsic cellular machinery to suppress interferon production

In a recent study posted to the bioRxiv* preprint server, researchers evaluated the mechanism of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)-associated inflammatory marker interferon (IFN) repression in hosts.

25 Jan 2022

Beta-amyloid deposits found in young patients with COVID-19

A new study describes the finding that patients of COVID-19 exhibit large amounts of focal β-amyloid deposits in their neocortical tissues.

25 Jan 2022

Impact of a third BNT162b2 dose on SARS-CoV-2 Omicron variant

In a new study, researchers assessed the extent and duration of the neutralization of SARS-CoV-2 Omicron variant of concern after the administration of two and three doses of the BNT162b2 mRNA vaccine.

25 Jan 2022

Evaluation of cross-reactive T cell responses between SARS-CoV-2 and common-cold human coronaviruses

A new study investigated SARS-CoV-2 spike protein responses targeted by cross-reactive T cells that were isolated from convalescent COVID-19 individuals along with previously uninfected donors.

25 Jan 2022

Sensitivity and specificity of a “spit and mail” SARS-CoV-2 serology test

A recent study evaluated the sensitivity and specificity of a “spit and mail” serology test.

25 Jan 2022

LA County study finds COVID-19 'herd immunity' unlikely

In a research letter published in the Journal of the American Medical Association (JAMA), researchers carried out a seroprevalence and vaccination coverage study in Los Angeles County (LAC).

24 Jan 2022

Assay News and Research

Exploring receptor-blocking conserved non-neutralizing antibodies for SARS-CoV-2 therapy

Intranasal interferon-λ treatment protects mice against SARS-CoV-2 Beta and Omicron variants

Low Dead Volume Reservoir Trays

Early-stage alveolar epithelial cell necrosis linked to COVID-19-induced acute respiratory distress syndrome

SARS-CoV-2 mutations and their impact on spike protein-specific T lymphocytes

Study suggests enhanced phosphorylation and increased abundance of SARS-CoV-2 nucleocapsid protein provide selective advantage

Recipients of inactivated COVID-19 vaccine (CoronaVac) can be successfully boosted with different vaccines

T-cell apoptosis linked to poor prognosis among COVID-19 patients

Study shows enduring T-cell immunity up to at least 1-year after SARS-CoV-2 infection

Cross-recognition of SARS-CoV-2 vaccine-elicited T cell responses among different variants

Antibodies against SARS-CoV-2 found to persist for up to 15 months after infection

The Role of Glycans in the Cell and Glycans Imaging Method

Anti-SARS-CoV-2 antibodies found in wild mustelids in France

Research says spill-over of SARS-CoV-2 from humans to cattle is possible

SARS-CoV-2 virus co-opts intrinsic cellular machinery to suppress interferon production

Beta-amyloid deposits found in young patients with COVID-19

Impact of a third BNT162b2 dose on SARS-CoV-2 Omicron variant

Evaluation of cross-reactive T cell responses between SARS-CoV-2 and common-cold human coronaviruses

Sensitivity and specificity of a “spit and mail” SARS-CoV-2 serology test

LA County study finds COVID-19 'herd immunity' unlikely

eBook: Using iPSCs models for human disease research and drug discovery eBook

How Omics Technologies Are Transforming Biological Research and Drug Discovery

How microplastics and bacteria interact to drive antibiotic resistance

Single-cell proteomics: Revealing proteome diversity from cellular heterogeneity to non-canonical biology

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